Normal allele: AA
The CD58 genetic variant is associated with risk of multiple sclerosis and rheumatoid arthritis.
Polymorphism rs2300747 is related to topics like this:
Research and publications:
19237575 The role of the CD58 locus in multiple sclerosis.
19865102 Multiple sclerosis susceptibility alleles in African Americans.
19898481 Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
20182566 The genetic aspects of multiple sclerosis.
20186855 What role for genetics in the prediction of multiple sclerosis?
20362272 Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to come.
21247752 Revealing the genetic basis of multiple sclerosis: are we there yet?
21280076 Aggregation of multiple sclerosis genetic risk variants in multiple and single case families.
22190364 Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
23730204 Progress in multiple sclerosis genetics.
27108704 Genetic polymorphism of cell adhesion molecules in Behçet's disease in the Chinese Han population.
27386562 Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.
28601281 Association of CD58 gene polymorphisms with NMO spectrum disorders in a Han Chinese population.
32257069 Association of CD58 polymorphism and multiple sclerosis in Malaysia: a pilot study.