Normal allele: CC
Increased risk of autoimmune diseases - systemic lupus erythematosus, vasculitis, celiac disease, and newly diagnosed diabetes mellitus after transplantation.
Polymorphism rs2069763 is related to topics like this:
Research and publications:
18598732 Vaccine immunogenetics: bedside to bench to population.
19073967 Shared and distinct genetic variants in type 1 diabetes and celiac disease
19356949 Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies
19951419 Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis.
20184734 The 4q27 locus and prostate cancer risk.
21829393 Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
21873553 Genetic analysis of adult-onset autoimmune diabetes.
22891215 Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes.
24281113 Inflammatory genetic markers of prostate cancer risk.
24309190 Genetics of new-onset diabetes after transplantation.
25037274 Autoimmune diseases association study with the KIAA1109-IL2-IL21 region in a Tunisian population.
25075970 The associations between immunity-related genes and breast cancer prognosis in Korean women.
28366330 Cytokine polymorphisms are associated with daytime napping in adults living with HIV.
30341786 Recurrent aphthous stomatitis and gene variability in selected interleukins: a case-control study.
30729267 IL-2 gene polymorphisms affect tacrolimus response in myasthenia gravis.