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Vitamin C DNA

vitamin-c

By Li Dali, Ph.D.

If you tested your DNA with a personal genomics service like 23andMe, AncestryDNA, FamilyTreeDNA, MyHeritage or another testing company, you can learn more about your risk factors for hundreds of diseases. By clicking the button above ⬆️, you can upload your raw DNA data file and receive a personalized 250-page health report with research links that is the most comprehensive.

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin essential for various bodily functions, serving as an antioxidant and a crucial cofactor in collagen biosynthesis, carnitine and catecholamine metabolism, and dietary iron absorption.

As humans cannot produce vitamin C internally, it must be obtained through dietary sources, particularly from fruits and vegetables such as citrus fruits, berries, tomatoes, potatoes, and leafy greens.

Genetic testing can provide insights into whether you may have a heightened need for vitamin C compared to others. If indicated, incorporating vitamin C supplements and fortified foods into your diet can be beneficial. Individuals with certain variations in the SLC23A1 gene may experience reduced circulating vitamin C levels, necessitating an increase in vitamin C-rich foods or consideration of daily supplementation.

Take the first step by uploading your DNA file from 23andMe, AncestryDNA, FamilyTreeDNA, or MyHeritage to uncover how your genetic makeup influences your dietary and nutritional requirements, among other factors.

Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Vitamin C and see a list of existing studies.

SNP polymorphisms related to the topic Vitamin C:

rs4257763The breakage causes a problem with the vitamin C transporter, the absorption of vitamin C from food, and a decrease in blood levels of ascorbic acid.
rs2681116Polymorphism of a gene for a vitamin C transporter gene from food and decreased blood ascorbic acid levels.
rs6139591Polymorphism of a gene for a vitamin C transporter gene from food and decreased blood ascorbic acid levels.
rs6596473One of two sodium-dependent transporters required for hepatic and renal reabsorption of vitamin C (ascorbic acid) and thus essential for maintaining vitamin C homeostasis in the blood.
rs33972313Causes a decrease in the transport activity of vitamin C. Causes a decrease in vitamin C levels regardless of diet.
rs1279683Associated with decreased blood levels of vitamin C and risk of glaucoma.
rs11950646
rs6053005
rs6133175
rs10063949

About The Author
Li Dali Li Dali

Li Dali, a National Foundation for Outstanding Youth Fund recipient, is a researcher at the School of Life Sciences in East China Normal University. He earned his PhD in genetics from Hunan Normal University in 2007 and conducted collaborative research at Texas A&M University during his doctoral studies. Li Dali and his team have optimized and innovated gene editing technology, leading to the establishment of a world-class system for constructing gene editing disease models.

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