
If you tested your DNA with a personal genomics service like 23andMe, AncestryDNA, FamilyTreeDNA, MyHeritage or another testing company, you can learn more about your risk factors for hundreds of diseases. By clicking the button above ⬆️, you can upload your raw DNA data file and receive a personalized 250-page health report with research links that is the most comprehensive.
Celiac disease (CD) is a chronic condition marked by an intolerance to gluten, primarily affecting the small intestine in individuals with a genetic predisposition. It typically resolves upon excluding gluten from the diet. CD entails nutrient malabsorption due to inflammatory damage to the small intestine's mucosa triggered by consuming wheat gluten or similar proteins found in rye, barley, and triticale (a wheat-rye hybrid).
The clinical presentation of CD varies based on factors such as age of onset, gender (with a female-to-male ratio of 2:1), severity of mucosal damage, and dietary patterns. Symptoms can range from typical gastrointestinal issues to atypical signs or even no symptoms at all.
The risk of celiac disease (or gluten intolerance) can be predicted by genetic testing for the HLA-DQ2 and HLA-DQ8 markers.
The TenDNA health DNA report analyzes single nucleotide polymorphisms related to Celiac disease. While this report isn't a diagnostic test, it holds negative predictive value, suggesting Celiac disease is improbable when the predisposing alleles are absent. A positive result suggests some genetic predisposition to Celiac, though overall likelihood remains low.
Upload your raw DNA data to receive your personalized Celiac Report completely free of charge.