Normal allele: TT
HLA DQ2.2 genes play an important role in many autoimmune diseases such as celiac disease, type 1 diabetes, rheumatoid arthritis, multiple sclerosis, psoriasis and others.
Polymorphism rs7775228 is related to topics like this:
Research and publications:
19458352 Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.
23868913 Advances in osteoarthritis genetics.
24876751 Allele and haplotype frequencies for HLA-DQ in Iranian celiac disease patients.
26214689 Genetic Loci Associated with Allergic Sensitization in Lithuanians.
27449795 Shared and unique common genetic determinants between pediatric and adult celiac disease.
27764105 Genome-Wide Meta-Analysis of Sciatica in Finnish Population.
33170161 Genetic test for the prescription of diets in support of physical activity.