Normal allele: TT
HLA DQ2.2 genes play an important role in many autoimmune diseases such as celiac disease, type 1 diabetes, rheumatoid arthritis, multiple sclerosis, psoriasis and others.
Polymorphism rs2395182 is related to topics like this:
Research and publications:
18832704 Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis.
24876751 Allele and haplotype frequencies for HLA-DQ in Iranian celiac disease patients.
27449795 Shared and unique common genetic determinants between pediatric and adult celiac disease.
33170161 Genetic test for the prescription of diets in support of physical activity.