SNP information rs1800693

Research and publications:

  17705862   Optimization of candidate-gene SNP-genotyping by flexible oligonucleotide microarrays; analyzing variations in immune regulator genes of hay-fever samples

  19525953   Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.

  19865102   Multiple sclerosis susceptibility alleles in African Americans.

  20062062   Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.

  20186855   What role for genetics in the prediction of multiple sclerosis?

  20217072   SNP/haplotype associations in cytokine and cytokine receptor genes and immunity to rubella vaccine.

  20362272   Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to come.

  20405052   The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.

  20837493   Genes that determine immunology and inflammation modify the basic defect of impaired ion conductance in cystic fibrosis epithelia.

  21247752   Revealing the genetic basis of multiple sclerosis: are we there yet?

  21399635   Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis.

  21523452   Genetic variation in proinflammatory cytokines IL6, IL6R, TNF-region, and TNFRSF1A and risk of breast cancer.

  21552549   The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study.

  22021740   Systematic review of genome-wide expression studies in multiple sclerosis.

  22164203   Perspectives on the use of multiple sclerosis risk genes for prediction.

  22190364   Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

  22346247   The role of ATG16L, NOD2 and IL23R in the pathogenesis of Crohn's disease.

  22396755   Genomic regions associated with multiple sclerosis are active in B cells.

  22801493   TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.

  22994200   Associations of CD6, TNFRSF1A and IRF8 polymorphisms with risk of inflammatory demyelinating diseases.

  23326239   A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1).

  23624563   TNFRSF1A polymorphisms rs1800693 and rs4149584 in patients with multiple sclerosis.

  23730204   Progress in multiple sclerosis genetics.

  24033266   A systematic approach to assessing the clinical significance of genetic variants.

  24174586   Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus.

  24661571   Laying a strong foundation for Manhattan—“laying a functional foundation for the post-GWAS era.”

  24790215   Stimulated PBMC-produced IFN-γ and TNF-α are associated with altered relapse risk in multiple sclerosis: results from a prospective cohort study.

  24927785   No association between identified multiple sclerosis non-MHC risk loci and neuromyelitis optica.

  25010932   Association of TNF-α, TNFRSF1A and TNFRSF1B gene polymorphisms with the risk of sporadic breast cancer in northeast Chinese Han women.

  25684197   Association of TNFAIP3 and TNFRSF1A variation with multiple sclerosis in a German case-control cohort.

  25690649   Multiple genetic variants associated with primary biliary cirrhosis in a Han Chinese population.

  25741868   Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.

  25915602   TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children.

  26249223   Reasoning over genetic variance information in cause-and-effect models of neurodegenerative diseases.

  27386562   Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation.

  27802296   A Risk Score for Predicting Multiple Sclerosis.

  27863251   Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.

  28139605   Analysis of the relationship between cytokine receptor gene polymorphisms and clinical features of multiple sclerosis.

  29034884   Generation of six multiple sclerosis patient-derived induced pluripotent stem cell lines.

  29285231   Association between TNFSF4, TNFSF8 and TNFSF15 and Behçet's disease but not VKH syndrome in Han Chinese.

  29401539   Associations of TNFRSF1A Polymorphisms with Autoimmune Thyroid Diseases: A Case-Control Study.

  29535371   The severity of ankylosing spondylitis and responses to anti-tumour necrosis factor biologics are not influenced by the tumour necrosis factor receptor polymorphism incriminated in multiple sclerosis.

  30009568   TNFRSF1A polymorphisms and their role in multiple sclerosis susceptibility and severity in the Slovak population.

  30643196   POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.33.

  32205584   Pharmacogenetics of antitumor necrosis factor therapy in severe sarcoidosis.

  32355262   Replication analysis of variants associated with multiple sclerosis risk.

  33603056   TNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNFα/TNFR1 signalling regulation in the pathophysiology of TRAPS.

  33751344   Association of TNFRSF1A and IFNLR1 Gene Polymorphisms with the Risk of Developing Breast Cancer and Clinical Pathologic Features.

  35074627   Mendelian randomization study on the causal effects of tumor necrosis factor inhibition on coronary artery disease and ischemic stroke among the general population.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.

  35294530   TNFRSF1B and TNF Variants Are Associated With Differences in Levels of Soluble Tumor Necrosis Factor Receptors in Patients With Severe COVID-19.

  35629038   Searching for New Genetic Biomarkers of Axial Spondyloarthritis.

  35891671   Predictors of progression from a first demyelinating event to clinically definite multiple sclerosis.