SNP information rs7923837

Research and publications:

  17786204   Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

  17928989   Variations in the HHEX gene are associated with increased risk of type 2 diabetes in the Japanese population.

  17971426   Polymorphisms in the IDE-KIF11-HHEX gene locus are reproducibly associated with type 2 diabetes in a Japanese population.

  18039816   A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study.

  18162508   Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population

  18231124   HHEX gene polymorphisms are associated with type 2 diabetes in the Dutch Breda cohort.

  18264689   Polymorphisms in the TCF7L2, CDKAL1 and SLC30A8 genes are associated with impaired proinsulin conversion

  18426861   Association analysis of type 2 diabetes Loci in type 1 diabetes

  18443202   Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies

  18461161   Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value

  18469204   Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians

  18477659   Replication of genome-wide association studies of type 2 diabetes susceptibility in Japan.

  18544707   Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.

  18556337   Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1)

  18633108   Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

  18654633   Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies

  18689899   Exchangeable models of complex inherited diseases

  19002430   Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population

  19033397   Replication study of candidate genes associated with type 2 diabetes based on genome-wide screening.

  19117022   The influence of genetic variations in HHEX gene on insulin metabolism in the German MESYBEPO cohort.

  19172244   The risk allele load accelerates the age-dependent decline in beta cell function.

  19368707   Contribution of type 2 diabetes associated loci in the Arabic population from Tunisia: a case-control study.

  19592620   Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene.

  19741467   Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea.

  19933996   Examination of all type 2 diabetes GWAS loci reveals HHEX-IDE as a locus influencing pediatric BMI.

  20043145   Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study

  20080751   Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3.

  20126254   Rare variants create synthetic genome-wide associations.

  20532014   The epidemiology of diabetes in Korea: from the economics to genetics.

  20550665   Association study of genetic variants in eight genes/loci with type 2 diabetes in a Han Chinese population.

  20580033   Replication of recently described type 2 diabetes gene variants in a South Indian population.

  20802253   Glycemia determines the effect of type 2 diabetes risk genes on insulin secretion

  21059810   Meta-analysis of the effect of HHEX gene polymorphism on the risk of type 2 diabetes.

  21103332   Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies

  21152029   Evaluation of fasting state-/oral glucose tolerance test-derived measures of insulin release for the detection of genetically impaired β-cell function

  21278902   Genetic risk profiling for prediction of type 2 diabetes

  21297524   The 1p13.3 LDL (C)-associated locus shows large effect sizes in young populations.

  21368910   Heterogeneity of genetic associations of CDKAL1 and HHEX with susceptibility of type 2 diabetes mellitus by gender.

  21444075   Type 2 diabetes susceptibility single-nucleotide polymorphisms are not associated with polycystic ovary syndrome.

  21799836   A genome-wide association study confirms previously reported loci for type 2 diabetes in Han Chinese.

  22052079   Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs.

  22164203   Perspectives on the use of multiple sclerosis risk genes for prediction.

  22333905   Estimating the contribution of genetic variants to difference in incidence of disease between population groups.

  22396755   Genomic regions associated with multiple sclerosis are active in B cells.

  22506066   Genetic variants of IDE-KIF11-HHEX at 10q23.33 associated with type 2 diabetes risk: a fine-mapping study in Chinese population.

  22768041   Allele summation of diabetes risk genes predicts impaired glucose tolerance in female and obese individuals

  22923468   Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population.

  23166797   Hematopoietically-expressed homeobox gene three widely-evaluated polymorphisms and risk for diabetes: a meta-analysis.

  23458876   ACE I/D and MTHFR C677T polymorphisms are significantly associated with type 2 diabetes in Arab ethnicity: a meta-analysis.

  23730204   Progress in multiple sclerosis genetics.

  24736664   Validation of type 2 diabetes risk variants identified by genome-wide association studies in Han Chinese population: a replication study and meta-analysis.

  24843659   Insights into the genetic basis of type 2 diabetes.

  25587982   Cumulative effect and predictive value of genetic variants associated with type 2 diabetes in Han Chinese: a case-control study.

  26042206   Gene-gene and gene-environment interactions in the etiology of type 2 diabetes mellitus in the population of Hyderabad, India.

  26648684   Update on genetics and diabetic retinopathy.

  27105501   Two variants on T2DM susceptible gene HHEX are associated with CRC risk in a Chinese population.

  27377502   Association of CDKAL1, CDKN2A/B & HHEX gene polymorphisms with type 2 diabetes mellitus in the population of Hyderabad, India.

  27589775   Validation of Type 2 Diabetes Risk Variants Identified by Genome-Wide Association Studies in Northern Han Chinese.

  27802296   A Risk Score for Predicting Multiple Sclerosis.

  28190082   Association of recently identified type 2 diabetes gene variants with Gestational Diabetes in Asian Indian population.

  31237015   HHEX gene polymorphisms and type 2 diabetes mellitus: A case-control report from Iran.

  35887298   Unraveling the Influence of HHEX Risk Polymorphism rs7923837 on Multiple Sclerosis Pathogenesis.