Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Infertility and miscarriage and see a list of existing studies.
SNP polymorphisms related to the topic Infertility and miscarriage:
|The study showed a 10% increase in total plasma homocysteine (tHcy)
|The rs6025(A) allele encodes a mutation known as the Leiden mutation, R506Q, an 11.4-fold increased risk of venous thromboembolism.
|Interleukin-18 promoter polymorphism increases the risk of idiopathic habitual miscarriage.
|1.25 times higher risk of non-obstructive azoospermia in men.
|STAT3 polymorphism is associated with idiopathic habitual miscarriages.
|G20210A mutation of the prothrombin F2 gene. 6.74-fold risk of thrombosis
|Decreases the activity of the NOS3 gene and may reduce the efficiency of the methylation process. Also associated with increased risk markers for cardiovascular problems, such as total cholesterol and low-density lipoprotein (LDL) levels, and with an increased risk of high blood pressure, especially in pregnant women.
|Moderate risk factor for hyperhomocysteinaemia. A factor that increases the body's need for folic acid and vitamin B12.
|A polymorphism of the chorionic gonadotropin luteinising hormone receptor gene (rs2293275) is associated with polycystic ovary syndrome.
|There is an increased risk of azoospermia (lack of sperm) and therefore male infertility.
|The common variant rs9939609 of the FTO gene, associated with fat mass and obesity, is associated with fat cell lipolysis as well as early onset of extreme obesity. Studies show that carriers of the risk allele A demonstrate significantly greater weight loss on a fat-restricted diet than non-carriers.
|Increased risk of idiopathic male infertility and non-obstructive azoospermia.
|Antioxidant enzymes and CAT binding are associated with the risk of idiopathic habitual miscarriage.
|Protamine gene polymorphism is associated with asthenozoospermia in men.