SNP information rs187238

Research and publications:

  15896202   Interleukin-18-promoter polymorphisms are not relevant in rheumatoid arthritis.

  16078996   Association study of functional genetic variants of innate immunity related genes in celiac disease.

  16443795   Analysis of polymorphisms of the interleukin-18 gene in type 1 diabetes and Hardy-Weinberg equilibrium testing.

  16542373   Interleukin 18 and human immunodeficiency virus type I infection in adolescents and adults.

  16759385   Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)

  16909454   NeuroD1 gene and interleukin-18 gene polymorphisms in type 1 diabetes in Dalmatian population of Southern Croatia.

  17355643   Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population

  17765248   Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: the Helsinki Sudden Death Study.

  17854431   Interleukin-18 gene polymorphisms and haplotypes in patients with oral lichen planus: a study in an ethnic Chinese cohort.

  17919265   Polymorphism of interleukin-18 promoter influences the onset of kidney graft function after transplantation.

  18043444   Interleukin (IL)-18 polymorphism 133C/G is associated with severe respiratory syncytial virus infection.

  18599493   Promoter polymorphism of interleukin-18 in angiographically proven coronary artery disease.

  19073159   Interleukin-18 promoter polymorphism and risk of late-onset Alzheimer's disease.

  19178691   Novel polymorphism of interleukin-18 associated with greater inflammation after cardiac surgery.

  19229765   Interleukin-18 gene (IL18) promoter polymorphisms in patients with rheumatoid arthritis.

  19455410   Interleukin 18 promoter variants (-137G>C and -607C>A) in patients with chronic hepatitis C: association with treatment response.

  19687159   Interleukin 18 gene promoter polymorphism: a link between hypertension and pre-hospital sudden cardiac death: the Helsinki Sudden Death Study.

  19961892   Impact of interleukin-18 polymorphisms-607 and -137 on clinical characteristics of renal cell carcinoma patients.

  20083555   Commonly studied polymorphisms in inflammatory cytokine genes show only minor effects on mortality and related risk factors in nonagenarians

  20097272   Interleukin-18 promoter polymorphisms and risk of ischemic stroke.

  20103664   Inherited determinants of ovarian cancer survival.

  20227257   Polymorphisms in the platelet-specific collagen receptor GP6 are associated with risk of nonfatal myocardial infarction in Caucasians

  20227263   Genetic variation within IL18 is associated with insulin levels, insulin resistance and postprandial measures.

  20304021   Haplotype analysis of the interleukin-18 gene in Czech patients with allergic disorders.

  20331879   Association between IL-18 gene polymorphisms and biopsy-proven giant cell arteritis.

  20406895   Genetic variants in inflammation pathway genes and asthma in glioma susceptibility

  20478055   Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study.

  20818961   Inflammatory mediators gene polymorphisms in preeclampsia.

  21149337   Dense mapping of IL18 shows no association in SLE.

  21241672   Interleukin-18 promoter polymorphism and risk of Parkinson's disease in a Chinese Han population.

  21470492   Interleukin-18 promoter polymorphisms in patients with systemic lupus erythematosus.

  21532063   IL18 polymorphism is associated with Behçet's disease but not with lupus in Turkish patients.

  21611751   Interleukin-18 promoter polymorphism and asthma risk: a meta-analysis.

  21840518   Analysis of interleukin-18 promoter polymorphisms and changes in interleukin-18 serum levels underscores the involvement of interleukin-18 in recurrent spontaneous miscarriage.

  21955043   Validation of single nucleotide polymorphisms associated with acute rejection in kidney transplant recipients using a large multi-center cohort.

  21962565   Promoter variants in IL18 are associated with onset of depression in patients previously exposed to stressful-life events.

  21969001   Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality.

  21984735   High plasma interleukin-18 levels mark the acute phase of hepatitis C virus infection.

  22008665   The associations of IL-18 serum levels and promoter polymorphism with tacrolimus pharmacokinetics and hepatic allograft dysfunction in Chinese liver transplantation recipients.

  22141572   Circulating levels of IL-18 are significantly influenced by the IL-18 +183 A/G polymorphism in coronary artery disease patients with diabetes type 2 and the metabolic syndrome: an observational study.

  22144535   Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study.

  22300735   Genetic predisposition factors and nasopharyngeal carcinoma risk: a review of epidemiological association studies, 2000-2011: Rosetta Stone for NPC: genetics, viral infection, and other environmental factors.

  22325058   Association of polymorphisms in interleukin-18 and interleukin-28B with hepatitis B recurrence after liver transplantation in Chinese Han population

  22386125   Interleukin-18 promoter polymorphisms and risk of idiopathic recurrent pregnancy loss in a Tunisian population.

  22664470   Interleukin-18 pathway genes are associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma.

  23073298   The IL18 gene and Hashimoto thyroiditis in children.

  23153245   Association of IL-18 polymorphisms with rheumatoid arthritis and systemic lupus erythematosus in Asian populations: a meta-analysis.

  23238919   Association between interleukin-18 polymorphisms and systemic lupus erythematosus: a meta-analysis.

  23302036   Gender-specific association of the interleukin 18 gene with symptomatic gallstone disease.

  23557801   Interleukin 18 (IL18) gene promoter polymorphisms are associated with type 1 diabetes mellitus in Brazilian patients.

  23587914   Interleukin-18 gene polymorphisms and rheumatoid arthritis: a meta-analysis.

  24069534   Genetics of psoriasis and pharmacogenetics of biological drugs.

  24176007   Potential association of pulmonary tuberculosis with genetic polymorphisms of toll-like receptor 9 and interferon-gamma in a Chinese population.

  24281113   Inflammatory genetic markers of prostate cancer risk.

  24349532   Impact of interleukin-18 polymorphisms -607A/C and -137G/C on oral cancer occurrence and clinical progression.

  24446726   Association between interleukin 18 polymorphisms and alopecia areata in Koreans.

  24621393   Genetic polymorphisms in the IL-18 gene and ulcerative colitis risk: a meta-analysis.

  24898701   Functional polymorphisms of interleukin-18 gene and risk of breast cancer in a Brazilian population.

  24909718   Analysis of the association of polymorphic loci rs917997 in the IL18RAP gene and rs187238 in the IL18 gene with the risk of developing non-Hodgkin malignant lymphomas in the Novosibirsk population.

  24969483   IL-18 genetic polymorphisms may contribute to the pathogenesis of tuberculosis among Asians: a meta-analysis of case-control studies.

  25192895   Association of IL-18 promoter gene polymorphisms with rheumatoid arthritis: a meta-analysis.

  25374428   Interleukin-18 gene promoter polymorphisms and celiac disease in Italian patients.

  25446437   Association of IL-1, IL-18, and IL-33 gene polymorphisms with late-onset Alzheimer׳s disease in a Hunan Han Chinese population.

  25487141   Association between interleukin-18 promoter variants and tacrolimus pharmacokinetics in Chinese renal transplant patients.

  25690033   Genetic variant in interleukin-18 is associated with idiopathic recurrent miscarriage in Chinese Han population.

  25712187   Donor IL-18 rs5744247 polymorphism as a new biomarker of tacrolimus elimination in Chinese liver transplant patients during the early post-transplantation period: results from two cohort studies.

  26026656   Ethnicity-stratified analysis of the association between IL-18 polymorphisms and systemic lupus erythematosus in a European population: a meta-analysis.

  26041375   A gene-disease association study of IL18 in thyroid cancer: genotype and haplotype analyses.

  26042207   Association between interleukin-18 gene promoter (- 607C/A and - 137G/C) polymorphisms and chronic hepatitis C virus infections: A meta-analysis.

  26096341   Association between interleukin-18 gene polymorphism and Helicobacter pylori infection in the Korean population.

  26116895   Interleukin-18 promoter -607 C/A and -137 G/C polymorphisms and susceptibility to type 1 diabetes: A meta-analysis.

  26213495   Association between IL-18 polymorphisms, serum levels, and HBV-related hepatocellular carcinoma in a Chinese population: a retrospective case-control study.

  26229413   Genetic polymorphisms of interleukin-18 have different effects on susceptibility to Crohn's disease.

  26438531   Increased IL18 mRNA levels in peripheral artery disease and its association with triglyceride and LDL cholesterol levels: a pilot study.

  26486291   ANALYSIS OF POLYMORPHISMS IN THE INTERLEUKIN 18 GENE PROMOTOR (-137 G/C AND -607 C/A) IN PATIENTS INFECTED WITH HEPATITIS C VIRUS FROM THE BRAZILIAN AMAZON.

  26600055   Single Nucleotide Polymorphism of Interleukin-18 and Interleukin-18 Receptor and the Risk of Papillary Thyroid Cancer.

  26690141   IL-18 and Cutaneous Inflammatory Diseases.

  26698117   Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort.

  26800664   Association of cytokine gene polymorphisms (IL-6, IL-12B, IL-18) with Behçet's disease: a meta-analysis.

  26830320   Lack of association between IL-10 and IL-18 gene promoter polymorphisms and Parkinson's disease with cognitive impairment in a Chinese population.

  26986131   Human Cytokine Genetic Variants Associated With HBsAg Reverse Seroconversion in Rituximab-Treated Non-Hodgkin Lymphoma Patients.

  27027876   IL18 Gene Variants Influence the Susceptibility to Chagas Disease.

  27054030   Dual roles of cytokines in Alzheimer's disease: update on interleukins, TNF-α, TGF-β, and IFN-β.

  27098064   Association of interleukin-1 family cytokines single nucleotide polymorphisms with susceptibility to systemic sclerosis: an independent case-control study and a meta-analysis.

  27247849   Genetic variation and cognitive dysfunction in opioid-treated patients with cancer.

  27376129   Independent Replication of Published Germline Polymorphisms Associated with Urinary Bladder Cancer Prognosis and Treatment Response.

  27419078   Interleukin-18 gene promoter 607A polymorphism, but not 137C polymorphism, is a protective factor for ischemic stroke in the Chinese population: A meta-analysis.

  27430614   A Functional Interleukin-18 Haplotype Predicts Depression and Anxiety through Increased Threat-Related Amygdala Reactivity in Women but Not Men.

  27454254   Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.

  27483258   Molecular Mechanisms of Cutaneous Inflammatory Disorder: Atopic Dermatitis.

  27689253   Role of Cytokine Gene Score in Risk Prediction of Premature Coronary Artery Disease.

  27703550   Serum Interleukin-18 and Its Gene Haplotypes Profile as Predictors in Patients with Diabetic Nephropathy.

  28000712   Genetic polymorphisms -137 (rs187238) and -607 (rs1946518) in the interleukin-18 promoter may not be associated with development of hepatocellular carcinoma.

  28526653   Genetic variants of interleukin-18 are associated with reduced risk of atrial fibrillation in a population from Northeast China.

  28580570   IL16 and IL18 gene polymorphisms in women with gestational diabetes.

  28834572   Multiple genetic variants associated with posttransplantation diabetes mellitus in Chinese Han populations.

  28973736   Interleukin-18 (rs187238) and glucose transporter 4 (rs5435) polymorphisms in Euro-Brazilians with type 1 diabetes.

  29061223   Association between donor and recipient Interleukin-18 gene polymorphisms and the risk of infection after liver transplantation.

  29113394   IL-18 polymorphisms contribute to hepatitis B virus-related cirrhosis and hepatocellular carcinoma susceptibility in Chinese population: a case-control study.

  29129846   The IL18 Promoter Polymorphism, rs1946518, Is Associated with the Risk of Periodontitis in Japanese Women: The Kyushu Okinawa Maternal and Child Health Study.