SNP information rs2070744

Research and publications:

  16820586   Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery

  17367796   Association of polymorphisms in NOS3 with the ankle-brachial index in hypertensive adults.

  17579350   NOS-I and -III gene variants are differentially associated with facets of suicidal behavior and aggression-related traits.

  17605790   Lack of association between endothelial nitric oxide synthase (NOS3) gene polymorphisms and suicide attempts.

  17980690   Polymorphisms in the endothelial nitric oxide synthase gene and bone density/ultrasound and geometry in humans.

  18246059   Habitual energy expenditure modifies the association between NOS3 gene polymorphisms and blood pressure.

  18279468   Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure.

  18506375   Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome.

  18698231   Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.

  18776599   Susceptibility genes for gentamicin-induced vestibular dysfunction.

  18936436   Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994

  19132956   A common variant of the eNOS gene (E298D) is an independent risk factor for left ventricular hypertrophy in human essential hypertension.

  19155013   The endothelial nitric oxide synthase -786 T>C polymorphism and the exercise-induced blood pressure and nitric oxide responses among men with elevated blood pressure.

  19423521   Genetic polymorphisms in nitric oxide synthase genes modify the relationship between vegetable and fruit intake and risk of non-Hodgkin lymphoma.

  19435423   Lack of association between matrix metalloproteinase-9 and endothelial nitric oxide synthase gene polymorphisms and coronary artery disease in Turkish population.

  19661472   Relation of candidate genes that encode for endothelial function to migraine and stroke: the Stroke Prevention in Young Women study.

  19701646   The -786 T/C polymorphism of the NOS3 gene is associated with elite performance in power sports.

  19815736   Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with sex and postmenopausal hormone use.

  19853644   Promoter polymorphisms of the NOS3 gene are associated with hypnotizability-dependent vascular response to nociceptive stimulation.

  20124951   Vascular endothelial growth factor pathway.

  20204503   The association between two polymorphisms of eNOS and breast cancer risk: a meta-analysis.

  20357209   Molecular genetic studies of gene identification for osteoporosis: the 2009 update

  20406466   Genetic variants associated with fasting blood lipids in the U.S. population: Third National Health and Nutrition Examination Survey

  20457799   Effects of eNOS polymorphisms on nitric oxide formation in healthy pregnancy and in pre-eclampsia.

  20459474   Can we predict top-level sports performance in power vs endurance events? A genetic approach.

  20581851   Exploring epistatic relationships of NO biosynthesis pathway genes in susceptibility to CHD.

  21048526   Doxorubicin pathways: pharmacodynamics and adverse effects.

  21054877   Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994

  21056700   Lack of replication in polymorphisms reported to be associated with atrial fibrillation.

  21058046   Genetics of salt-sensitive hypertension.

  21127830   Genetic associations in diabetic nephropathy: a meta-analysis.

  21149552   Heterogeneity of the phenotypic definition of coronary artery disease and its impact on genetic association studies.

  21204206   Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population

  21293869   Influence of endothelial nitric oxide synthase polymorphisms in psoriasis risk.

  21332392   Endothelial nitric oxide synthase haplotypes associated with aura in patients with migraine.

  21437030   Genetics and cardiovascular system: influence of human genetic variants on vascular function.

  21467728   Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.

  21472143   Association between polymorphisms in cancer-related genes and early onset of esophageal adenocarcinoma.

  21537392   Endothelin-1 and endothelial nitric oxide polymorphisms in idiopathic pulmonary arterial hypertension.

  21540342   Genes and elite athletes: a roadmap for future research.

  21577011   NCAM1, TACR1 and NOS genes and temperament: a study on suicide attempters and controls.

  21670344   Endothelial nitric oxide synthase gene variants and primary open-angle glaucoma: interactions with hypertension, alcohol intake, and cigarette smoking.

  21674837   Association of NOS3 tag polymorphisms with hypoxic-ischemic encephalopathy.

  21703358   Polymorphisms in nitric-oxide synthase 3 may influence the risk of urinary-bladder cancer.

  21886581   Genetic Association Analysis of NOS3 and Methamphetamine-Induced Psychosis Among Japanese.

  21894447   Are centenarians genetically predisposed to lower disease risk?

  21963893   Polymorphisms of genes in nitric oxide-forming pathway associated with ischemic stroke in Chinese Han population.

  22025889   Reproductive factors and NOS3 variant interactions in primary open-angle glaucoma.

  22064666   Endothelial nitric oxide synthase genotypes and haplotypes modify the responses to sildenafil in patients with erectile dysfunction.

  22135769   Gene-drug interaction in stroke.

  22184326   Genomewide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase.

  22194275   Histological and genetic studies in patients with bicuspid aortic valve and ascending aorta complications.

  22325930   Correlates of endothelial function and the peak systolic blood pressure response to a graded maximal exercise test.

  22470539   Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study.

  22499569   Allele C in the NOS3-786 T/C polymorphism is associated with elite football player status.

  22570788   Polymorphisms and haplotypes in candidate genes related to angiogenesis and endothelial dysfunction in preeclampsia.

  22594584   A novel multiplex PCR-RFLP method for simultaneous detection of the MTHFR 677 C > T, eNOS +894 G > T and - eNOS -786 T > C variants among Malaysian Malays.

  22817530   Genetic polymorphisms located in genes related to immune and inflammatory processes are associated with end-stage renal disease: a preliminary study.

  22865486   Interaction among nitric oxide (NO)-related genes in migraine susceptibility.

  22879966   Systematic testing of literature reported genetic variation associated with coronary restenosis: results of the GENDER Study.

  22919264   No difference in genotype frequencies of polymorphisms of the nitric oxide pathway between Caucasian normal and high tension glaucoma patients.

  23049672   Top Three Pharmacogenomics and Personalized Medicine Applications at the Nexus of Renal Pathophysiology and Cardiovascular Medicine.

  23062210   eNOS tag SNP haplotypes in hypertensive disorders of pregnancy.

  23176758   Association of nitric oxide synthase gene polymorphisms (-786T>C, 4a4b, 894G>T) with primary ovarian insufficiency in Korean women.

  23333443   Analysis of polymorphisms and haplotypes in genes associated with vascular tone, hypertension and oxidative stress in Mexican-Mestizo women with severe preeclampsia.

  23681449   Genes for elite power and sprint performance: ACTN3 leads the way.

  23776350   Gene polymorphisms in association with self-reported stroke in US adults.

  23826716   Association analysis of nitric oxide synthases: NOS1, NOS2A and NOS3 genes, with multiple sclerosis.

  23940833   Playing with heart and soul…and genomes: sports implications and applications of personal genomics.

  24035903   The -974C>A (rs3087459) gene polymorphism in the endothelin gene (EDN1) is associated with risk of developing acute coronary syndrome in Mexican patients.

  24095258   Polymorphisms of the NOS3 gene and risk of myocardial infarction in the Tunisian population.

  24168396   Genetic variation in CD36, HBA, NOS3 and VCAM1 is associated with chronic haemolysis level in sickle cell anaemia: a longitudinal study.

  24292621   Genetic association of rs1800780 (A→G) polymorphism of the eNOS gene with susceptibility to essential hypertension in a Chinese Han population.

  24932102   Endothelin-1 but not Endothelial Nitric Oxide Synthase Gene Polymorphism is Associated with Sickle Cell Disease in Africa.

  24940036   Endothelial nitric oxide synthase polymorphisms and susceptibility to high-tension primary open-angle glaucoma in an Egyptian cohort.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  24972130   Association of the NOS3 intron-4 VNTR polymorphism with aneurysmal subarachnoid hemorrhage.

  25140814   Association of NOS3 gene variants and clinical contributors of hypoxic-ischemic encephalopathy.

  25320160   Multi-level biomarker analysis of nitric oxide synthase isoforms in bipolar disorder and adult ADHD.

  25475491   Association between endothelial NO synthase polymorphisms and arterial properties in the general population.

  25512783   Association of genetic variants with diabetic nephropathy.

  25544888   Gender-related associations of genetic polymorphisms of α-adrenergic receptors, endothelial nitric oxide synthase and bradykinin B2 receptor with treadmill exercise test responses.

  25685286   Adiponectin: Probe of the molecular paradigm associating diabetes and obesity.

  26172140   Genetic Contributions to the Development of Complications in Preterm Newborns.

  26191352   Association of endothelial nitric oxide synthase gene T-786C promoter polymorphism with gastric cancer.

  26298202   Outcome after BCG treatment for urinary bladder cancer may be influenced by polymorphisms in the NOS2 and NOS3 genes.

  26335431   Altered erythrocyte membrane protein composition mirrors pleiotropic effects of hypertension susceptibility genes and disease pathogenesis.

  26627480   Genetic predisposition to acute kidney injury--a systematic review.

  26648684   Update on genetics and diabetic retinopathy.

  26690118   An Updated Review on the Genetics of Primary Open Angle Glaucoma.

  27004986   New Findings in eNOS gene and Thalidomide Embryopathy Suggest pre-transcriptional effect variants as susceptibility factors.

  27038349   Age and gender differences in the influences of eNOS T-786C polymorphism on arteriosclerotic parameters in general population in Japan.

  27242919   Association of Common Variants in eNOS Gene with Primary Open Angle Glaucoma: A Meta-Analysis.

  27277665   Genetic risk factors for restenosis after percutaneous coronary intervention in Kazakh population.

  27448535   Differences in biochemical and genetic biomarkers in patients with heart failure of various etiologies.

  27594880   Association of eNOS Gene Polymorphisms G894T and T-786C with Risk of Hepatorenal Syndrome.

  27696692   Gene-Gene Interactions Among PRKCA, NOS3 and BDKRB2 Polymorphisms Affect the Antihypertensive Effects of Enalapril.

  27711207   Genetic Modifiers of White Blood Cell Count, Albuminuria and Glomerular Filtration Rate in Children with Sickle Cell Anemia.

  27871254   Familial aggregation of albuminuria and arterial hypertension in an Aboriginal Australian community and the contribution of variants in ACE and TP53.