Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Hypertension and see a list of existing studies.
SNP polymorphisms related to the topic Hypertension:
|The ADD1 gene variant is associated with the progression of blood pressure and the occurrence of hypertension. The risk of arterial hypertension is increased by 1.8 times. Increased sensitivity of blood pressure to salt, good response to salt-restricted diet.
|Phosphorylation-related variant ADD1 rs4963 affects blood pressure sensitivity to salt.
|A polymorphism known as A1166C, one of the most studied genes, is associated with an increased risk of essential hypertension with an odds ratio of 7.3 (CC homozygote).
|The rs1126742 polymorphism of the cytochrome P450 gene is associated with essential hypertension in men.
|A polymorphism with an increased risk of hypertension treatable with hydrochlorothiazide as first-line therapy, without a beta-blocker and without a vasodilator.
|Decreases the activity of the NOS3 gene and may reduce the efficiency of the methylation process. Also associated with increased risk markers for cardiovascular problems, such as total cholesterol and low-density lipoprotein (LDL) levels, and with an increased risk of high blood pressure, especially in pregnant women.
|Polymorphism of a conserved beta(1)-adrenergic receptor motif alters cardiac function and is associated with acute coronary syndrome and cardiovascular risk factors.
|STK39 polymorphism is an independent risk factor for hypertension in men.
|A break in the NEDD4L gene is associated with significantly higher diastolic blood pressure.
|Genetic variation in NEDD4L is associated with transverse and longitudinal blood pressure. Increases the risk of hypertension and adverse cardiovascular outcomes in patients with arterial hypertension treated with thiazide diuretics. Associated with favourable response to treatment with beta-blockers and diuretics in patients with arterial hypertension.