SNP information rs1801253

Research and publications:

  10212248   A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor.

  12374873   Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure.

  16120061   The functional significance of genetic variation within the beta-adrenoceptor.

  16844790   A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure.

  17150099   Beta2-adrenergic receptor and UCP3 variants modulate the relationship between age and type 2 diabetes mellitus.

  17335470   Studies of associations between the Arg389Gly polymorphism of the beta1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects.

  17496726   Synergistic polymorphisms of beta1 and alpha2C-adrenergic receptors and the influence on left ventricular ejection fraction response to beta-blocker therapy in heart failure.

  17512307   Association analyses of adrenergic receptor polymorphisms with obesity and metabolic alterations.

  18059082   Association of ADRB1 and UCP3 gene polymorphisms with insulin sensitivity but not obesity.

  18187665   Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease.

  18534365   Common beta-adrenergic receptor polymorphisms are not associated with risk of sudden cardiac death in patients with coronary artery disease.

  18615004   beta-adrenergic receptor gene polymorphisms and beta-blocker treatment outcomes in hypertension.

  18794727   Genetic and gene expression studies implicate renin and endothelin-1 in edema caused by peroxisome proliferator-activated receptor gamma agonists.

  19379518   Development of a fingerprinting panel using medically relevant polymorphisms.

  19553224   Trp64Arg polymorphism in ADRB3 gene is associated with elite endurance performance.

  19743955   Polymorphisms of the beta1-adrenergic receptor gene are associated with essential hypertension in Chinese.

  19842931   GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans.

  20401335   Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype.

  20521218   Progress toward genetic tailoring of heart failure therapy.

  20565774   Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project

  20869266   Single-nucleotide polymorphisms in the β-adrenergic receptor genes are associated with lung allograft utilization.

  20921971   Mapping genes that predict treatment outcome in admixed populations.

  20952631   Association of single-nucleotide polymorphisms from 17 candidate genes with baseline symptom-limited exercise test duration and decrease in duration over 20 years: the Coronary Artery Risk Development in Young Adults (CARDIA) fitness study.

  20981351   Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study.

  21172166   Pharmacogenetics of antidepressant response.

  21395649   Association of beta-adrenergic receptor polymorphisms and mortality in carvedilol-treated chronic heart-failure patients.

  21414566   β2 adrenergic receptor polymorphisms and nocturnal blood pressure dipping status in the Wisconsin Sleep Cohort Study.

  21444836   Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals.

  21807569   β-1 and β-2 adrenergic receptor polymorphism and association with cardiovascular response to orthostatic screening.

  21894447   Are centenarians genetically predisposed to lower disease risk?

  21953487   Beyond genome-wide association studies: new strategies for identifying genetic determinants of hypertension.

  22024213   A novel gene-environment interaction involved in endometriosis

  22495925   Genetic polymorphisms inside and outside the MHC improve prediction of AS radiographic severity in addition to clinical variables.

  22552919   Bioinformatics and variability in drug response: a protein structural perspective.

  22683993   A mutation-centric approach to identifying pharmacogenomic relations in text.

  22703382   Effect of the Arg389Gly β₁-adrenoceptor polymorphism on plasma renin activity and heart rate, and the genotype-dependent response to metoprolol treatment.

  22938532   Sequencing and analysis of a South Asian-Indian personal genome.

  23065660   GNAS A-1121G variant is associated with improved diastolic dysfunction in response to exercise training in heart failure patients.

  23575227   The chromosome 3q25 genomic region is associated with measures of adiposity in newborns in a multi-ethnic genome-wide association study.

  23820649   Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease

  23856471   Identification of a KCNQ1 polymorphism acting as a protective modifier against arrhythmic risk in long-QT syndrome.

  24332148   Genetic variation in the β1-adrenergic receptor is associated with the risk of atrial fibrillation after cardiac surgery.

  25266489   Genetic polymorphisms of VIP variants in the Tajik ethnic group of northwest China.

  26091847   Genetic polymorphisms of pharmacogenomic VIP variants in the Uygur population from northwestern China.

  26111150   Association of the ADRB2 (rs2053044) polymorphism and angiotensin-converting enzyme-inhibitor blood pressure response in the African American Study of Kidney Disease and Hypertension.

  26602751   Association of β-Adrenergic Receptor Gene Polymorphisms With Acute Coronary Syndrome and Cardiovascular Risk Factors in an Arab Population.

  26602921   A Multiple Interaction Analysis Reveals ADRB3 as a Potential Candidate for Gallbladder Cancer Predisposition via a Complex Interaction with Other Candidate Gene Variations.

  26694722   Correlation of ADRB1 rs1801253 Polymorphism with Analgesic Effect of Fentanyl After Cancer Surgeries.

  26879662   Impact of the β-1 adrenergic receptor polymorphism on tolerability and efficacy of bisoprolol therapy in Korean heart failure patients: association between β adrenergic receptor polymorphism and bisoprolol therapy in heart failure (ABBA) study.

  27103841   Personalized medicine and treatment approaches in hypertension: current perspectives.

  27108086   Multiplex SNaPshot-a new simple and efficient CYP2D6 and ADRB1 genotyping method.

  27233804   Genetic polymorphisms of pharmacogenomic VIP variants in the Mongol of Northwestern China.

  27247849   Genetic variation and cognitive dysfunction in opioid-treated patients with cancer.

  27480026   Genome Wide Association Study Identifies L3MBTL4 as a Novel Susceptibility Gene for Hypertension.

  27589963   Discrepancies between human DNA, mRNA and protein reference sequences and their relation to single nucleotide variants in the human population.

  27669015   Adrenergic Receptor Polymorphism and Maximal Exercise Capacity after Orthotopic Heart Transplantation.

  29587766   ADRB3 polymorphism rs4994 (Trp64Arg) associates significantly with bodyweight elevation and dyslipidaemias in Saudis but not rs1801253 (Arg389Gly) polymorphism in ARDB1.

  30387422   [Genetic Polymorphisms Associated with the Onset of Arterial Hypertension in a Portuguese Population].

  30668166   β(2)-Adrenergic Receptor Gene Polymorphisms Are Associated with Cardiovascular Events But not All-Cause Mortality in Coronary Artery Disease Patients: A Meta-Analysis of Prospective Studies.

  30753253   β1-Adrenoreceptor Polymorphisms and Blood Pressure: 49S Variant Increases Plasma Renin But Not Blood Pressure in Hypertensive Patients.

  30756358   Association of Genetic Polymorphisms in the Beta-1 Adrenergic Receptor with Recovery of Left Ventricular Ejection Fraction in Patients with Heart Failure.

  31056593   POLYMORPHISMS IN β-ADRENERGIC RECEPTORS ARE ASSOCIATED WITH INCREASED RISK TO HAVE A POSITIVE HEAD-UP TILT TABLE TEST IN PATIENTS WITH VASOVAGAL SYNCOPE.

  31469255   A genome-wide association and replication study of blood pressure in Ugandan early adolescents.

  32398726   Genetic Polymorphisms, Mediterranean Diet and Microbiota-Associated Urolithin Metabotypes can Predict Obesity in Childhood-Adolescence.

  32586526   Variants in ADRB1 and CYP2C9: Association with Response to Atenolol and Losartan in Marfan Syndrome.

  33053571   The role of Beta-1 receptor gene polymorphism in Beta-Blocker therapy for vasovagal syncope.

  33451866   Influence of ADRB1, ADRB2, and COMT Genetic Polymorphisms on Postoperative Outcomes of Patients Undergoing Cardiac Valve Surgery.

  33572708   Association of Genetic Variances in ADRB1 and PPARGC1a with Two-Kilometre Running Time-Trial Performance in Australian Football League Players: A Preliminary Study.

  33688237   Whole-Exome Sequencing in Patients Affected by Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Reveals New Variants Potentially Contributing to the Phenotype.

  34131278   Genetic polymorphisms associated with obesity in the Arab world: a systematic review.

  34638656   Towards Understanding the Genetic Nature of Vasovagal Syncope.

  34713976   β1-receptor polymorphisms and junctional ectopic tachycardia in children after cardiac surgery.

  34716504   Investigating changes in β-adrenergic gene expression (ADRB1 and ADRB2) in Takotsubo (stress) cardiomyopathy syndrome; a pilot study.

  35099251   Beta-adrenergic receptors gene polymorphisms are associated with cardiac contractility and blood pressure variability.

  35199539   Adrenergic receptors gene polymorphisms and autonomic nervous control of heart and vascular tone.

  35258481   Genetic biomarkers of life-threatening pheochromocytoma-induced cardiomyopathy.