SNP information rs4149601
Normal allele: GG
Genetic variation in NEDD4L is associated with transverse and longitudinal blood pressure. Increases the risk of hypertension and adverse cardiovascular outcomes in patients with arterial hypertension treated with thiazide diuretics. Associated with favourable response to treatment with beta-blockers and diuretics in patients with arterial hypertension.
Polymorphism rs4149601 is related to topics like this:
Abnormally high blood pressure in the arteries, which transport blood from the heart to the rest of...
Research and publications:
19156173 Suggestive linkage of ADHD to chromosome 18q22 in a young genetically isolated Dutch population.
20038744 Human Nedd4L rs4149601 G allele generates evolutionary new isoform I with C2 domain.
21058046 Genetics of salt-sensitive hypertension.
21060895 Identification of candidate genes for dyslexia susceptibility on chromosome 18.
21573014 Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension.
22992668 Pharmacogenomics knowledge for personalized medicine.
27103841 Personalized medicine and treatment approaches in hypertension: current perspectives.
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