Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Stomach cancer and see a list of existing studies.
SNP polymorphisms related to the topic Stomach cancer:
|Disorders of intracellular metabolism of cobalamin. Positive effect on the efficacy of folic acid therapy in patients with hyperhomocysteinaemia.
|The APOE-E4 allele has a strong influence on the risk of developing Alzheimer's disease. One meta-analysis estimated the odds ratio for individuals homozygous for rs429358 to be 12 times higher for late-onset Alzheimer's disease and 61 times higher for early-onset disease. People with APOE4-4 allele C genotype should avoid eating animals raised on plants/grains that have higher levels of omega-6 compared to omega-3. It is advisable to practice vegetarianism to avoid all animal fats and measure the ratio of omega-3 to omega-6 in these people. Also, people with APOE 4 may do better on unmethylated forms of B12.
|Possible increased risk of fetal birth defects. A 1.5-fold higher risk for Caucasian mothers to give birth to children with DNT (neural tube defect). The association in children with this mutation with an increased risk of heart defects is greater if their mother did not get enough folic acid during pregnancy. The risk is reduced with adequate levels of folic acid and vitamin B6.
|There is a 1.9 times increased risk of stomach and oesophageal cancer.
|Increased risk of stomach and bladder cancer.
|Together with the rs4988889 gene breakage, it is a diagnostic criterion for celiac disease.
|Polymorphism affecting serum levels of magnesium, potassium and sodium. Also associated with risk of gastric cancer.
|Validation of IRF5 as a multiple sclerosis risk gene: putative role in human herpes virus-6 infection.
|Reduced conversion of beta-carotene to retinol. Supplemental retinol intake is recommended.