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SNP information rs2294008

RS2294008

Normal allele: CC

Increased risk of stomach and bladder cancer.

Polymorphism rs2294008 is related to topics like this:

Hereditary gastric cancer

Gastric cancer is the third leading cause of cancer-related deaths worldwide, with a 5-year...


Research and publications:

  19554573   Two genetic variants in prostate stem cell antigen and gastric cancer susceptibility in a Chinese population.

  19582881   Association of prostate stem cell antigen gene polymorphisms with the risk of stomach cancer in Japanese.

  19648920   Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer.

  19906782   Genome-wide association studies in cancer--current and future directions.

  20083643   Genetic variation in PSCA and bladder cancer susceptibility in a Chinese population.

  20131315   Genetic variation of PSCA gene is associated with the risk of both diffuse- and intestinal-type gastric cancer in a Chinese population.

  20230293   Association and haplotype analysis of prostate stem cell antigen with gastric cancer in Tibetans.

  20505153   A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

  20585100   Genome-wide association studies of cancer.

  20729852   A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma.

  20972438   A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.

  21064099   Genetic variant in PSCA predicts survival of diffuse-type gastric cancer in a Chinese population.

  21070776   Genetic variation in the prostate stem cell antigen gene and upper gastrointestinal cancer in white individuals.

  21070779   A functional single nucleotide polymorphism in mucin 1, at chromosome 1q22, determines susceptibility to diffuse-type gastric cancer.

  21081471   Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control study

  21268123   Polymorphisms in prostate stem cell antigen gene rs2294008 increase gastric cancer risk in Chinese.

  21427165   Genetic variants at 1q22 and 10q23 reproducibly associated with gastric cancer susceptibility in a Chinese population.

  21459758   Chromosome 4p16.3 variant modify bladder cancer risk in a Chinese population.

  21538581   Association of a common genetic variant in prostate stem-cell antigen with gastric cancer susceptibility in a Korean population.

  21681742   Prostate stem-cell antigen gene is associated with diffuse and intestinal gastric cancer in Caucasians: results from the EPIC-EURGAST study.

  21750109   European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene.

  21907010   Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection.

  21927616   Genetic susceptibility to bladder cancer risk and outcome.

  22037551   A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.

  22387998   A genome-wide association study identifies two susceptibility loci for duodenal ulcer in the Japanese population.

  22416122   Common genetic variants in the PSCA gene influence gene expression and bladder cancer risk.

  22426141   Prostate stem cell antigen polymorphisms and susceptibility to gastric cancer: a systematic review and meta-analysis.

  22481254   The PSCA polymorphisms derived from genome-wide association study are associated with risk of gastric cancer: a meta-analysis.

  22711262   Systematic evaluation of bladder cancer risk-associated single-nucleotide polymorphisms in a Chinese population.

  22768238   A microRNA-7 binding site polymorphism in HOXB5 leads to differential gene expression in bladder cancer.

  22824379   Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: a case-control and immunohistochemical study.

  23266392   Genetic variant as a selection marker for anti-prostate stem cell antigen immunotherapy of bladder cancer.

  23330817   Evolution of the concept of androgen-sensitive bladder cancer.

  23397433   Gender-specific differences in muscle-invasive bladder cancer: the concept of sex steroid sensitivity.

  23397970   Interpersonal and genetic origins of adult attachment styles: a longitudinal study from infancy to early adulthood.

  23988503   PSCA gene variants (rs2294008 and rs2978974) confer increased susceptibility of gallbladder carcinoma in females.

  24146278   Quantitative assessment of the influence of prostate stem cell antigen polymorphisms on gastric cancer risk.

  24155119   Genetic score of multiple risk-associated single nucleotide polymorphisms is a marker for genetic susceptibility to bladder cancer.

  24654646   Genetic variants at 8q24 are associated with risk of esophageal squamous cell carcinoma in a Chinese population.

  24740636   Cumulative effect of genome-wide association study-identified genetic variants for bladder cancer.

  24782603   Role of gene polymorphisms in gastric cancer and its precursor lesions: current knowledge and perspectives in Latin American countries.

  24810688   Mucin 1 gene (MUC1) and gastric-cancer susceptibility.

  24962126   Genetic and intermediate phenotypic susceptibility markers of gastric cancer in Hispanic Americans: a case-control study.

  25582162   Influence of prostate stem cell antigen gene polymorphisms on susceptibility to Helicobacter pylori-associated diseases: a case-control study.

  25624885   Association between PSCA mRNA expression levels and rs2294008 polymorphism in transitional cell cancer of the bladder.

  25658482   Associations of genetic variants in the PSCA, MUC1 and PLCE1 genes with stomach cancer susceptibility in a Chinese population.

  25721731   Association of PSCA rs2294008 gene variants with poor prognosis and increased susceptibility to gastric cancer and decreased risk of duodenal ulcer disease.

  25727947   rs2294008T, a risk allele for gastric and gallbladder cancers, suppresses the PSCA promoter by recruiting the transcription factor YY1.

  25731870   Genetic variation and gastric cancer risk: a field synopsis and meta-analysis.

  26006239   The Influence of PSCA Gene Variation on Its Expression and Gastric Adenocarcinoma Susceptibility in the Northwest Chinese Population.

  26109531   Functional annotation of high-quality SNP biomarkers of gastric cancer susceptibility: the Yin Yang of PSCA rs2294008.

  26129866   Genome-wide association study of gastric adenocarcinoma in Asia: a comparison of associations between cardia and non-cardia tumours.

  26308216   PSCA rs2294008 Polymorphism with Increased Risk of Cancer.

  26602921   A Multiple Interaction Analysis Reveals ADRB3 as a Potential Candidate for Gallbladder Cancer Predisposition via a Complex Interaction with Other Candidate Gene Variations.

  26659608   A Novel Electrochemical Microfluidic Chip Combined with Multiple Biomarkers for Early Diagnosis of Gastric Cancer.

  26785734   PSCA acts as a tumor suppressor by facilitating the nuclear translocation of RB1CC1 in esophageal squamous cell carcinoma.

  26848528   PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population.

  26891331   Impact of DCC (rs714) and PSCA (rs2294008 and rs2976392) Gene Polymorphism in Modulating Cancer Risk in Asian Population.

  26937134   Molecular alterations in gastric cancer with special reference to the early-onset subtype.

  27001215   PSCA rs2294008 polymorphism contributes to the decreased risk for cervical cancer in a Chinese population.

  27050280   Single-nucleotide polymorphisms in PSCA and the risk of breast cancer in a Chinese population.

  27079684   Genome-wide association studies and epigenome-wide association studies go together in cancer control.

  27116470   Prognostic Significance of Tag SNP rs1045411 in HMGB1 of the Aggressive Gastric Cancer in a Chinese Population.

  27127881   Risk prediction for early-onset gastric carcinoma: a case-control study of polygenic gastric cancer in Han Chinese with hereditary background.

  28220687   Environmental factors, seven GWAS-identified susceptibility loci, and risk of gastric cancer and its precursors in a Chinese population.

  28348449   Combined Genetic Biomarkers Confer Susceptibility to Risk of Urothelial Bladder Carcinoma in a Saudi Population.

  28652652   Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update.

  28808221   Genetic variation of the PSCA gene (rs2294008) is not associated with the risk of prostate cancer.

  28881685   Association between PSCA gene polymorphisms and the risk of cancer: an updated meta-analysis and trial sequential analysis.

  29028942   Association of high-evidence gastric cancer susceptibility loci and somatic gene expression levels with survival.

  29138729   Association of rs2294008 and rs9297976 Polymorphisms in PSCA Gene with Gastric Cancer Susceptibility in Uzbekistan.

  29423095   Decrease in PSCA expression caused by Helicobacter pylori infection may promote progression to severe gastritis.

  29732392   Bladder Cancer Genetic Susceptibility. A Systematic Review.

  29844822   Correlation between prostate stem cell antigen gene expression and oral squamous cell carcinoma.

  30189721   Genome-Wide Association of Genetic Variation in the PSCA Gene with Gastric Cancer Susceptibility in a Korean Population.

  30407486   Variants in the PSCA gene associated with risk of cancer and nonneoplastic diseases: systematic research synopsis, meta-analysis and epidemiological evidence.

  31008939   Contribution of prostate stem cell antigen variation rs2294008 to the risk of bladder cancer.

  31213476   Prostate Stem Cell Antigen Gene Polymorphism Is Associated with H. pylori-related Promoter DNA Methylation in Nonneoplastic Gastric Epithelium.

  31416884   Impact of PSCA gene polymorphisms in modulating gastric cancer risk in the Chinese population.

  31516756   Genetic polymorphisms and gastric cancer risk: a comprehensive review synopsis from meta-analysis and genome-wide association studies.

  31839644   Impact of PSCA Polymorphisms on the Risk of Duodenal Ulcer.

  32660489   Association of MUC1 5640G>A and PSCA 5057C>T polymorphisms with the risk of gastric cancer in Northern Iran.

  32664326   Evolutionary History of the Risk of SNPs for Diffuse-Type Gastric Cancer in the Japanese Population.

  32777176   Predictive model for risk of gastric cancer using genetic variants from genome-wide association studies and high-evidence meta-analysis.

  33128686   Polymorphisms PSCA rs2294008, IL-4 rs2243250 and MUC1 rs4072037 are associated with gastric cancer in a high risk population.

  33213418   Mediation by differential DNA methylation of known associations between single nucleotide polymorphisms and bladder cancer risk.

  33667608   Single nucleotide polymorphisms of whole genes and atrophic gastritis susceptibility:a systematic review and meta-analysis.

  35274594   The role of single-nucleotide polymorphisms of the 8q24 chromosome region in patients with concomitant bladder and prostate cancer.

  35477151   Hybridization chain reaction-mediated Fe(2)MoO(4) bimetallic nanozyme for colorimetric risk prediction of bladder cancer.

  36010338   SNP rs2920280 in PSCA Is Associated with Susceptibility to Gastric Mucosal Atrophy and Is a Promising Biomarker in Japanese Individuals with Helicobacter pylori Infection.

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