SNP information rs6679677

Research and publications:

  17554260   Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

  18224312   Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment

  18274536   Genome-wide association studies: progress and potential for drug discovery and development.

  18305142   PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes

  18533027   Worldwide population differentiation at disease-associated SNPs

  18794853   Common variants at CD40 and other loci confer risk of rheumatoid arthritis

  18853133   Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

  19168599   Type 1 diabetes in the BB rat: a polygenic disease.

  19474294   Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

  19565500   Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis

  19639606   Correcting the “winner's curse” in odds ratios based on genome-wide association results for major complex human diseases.

  19956648   Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases.

  20017963   Representation of genetic association via attributable familial relative risks in order to identify polymorphisms functionally relevant to rheumatoid arthritis.

  20088021   Screen and clean: a tool for identifying interactions in genome-wide association studies.

  20089178   Allelic variants in the PHTF1-PTPN22, C12orf30 and CD226 regions as candidate susceptibility factors for the type 1 diabetes in the Estonian population.

  20122189   Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso.

  20362271   Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record.

  20442747   Genome-wide gene and pathway analysis.

  20549515   Genome-wide searching of rare genetic variants in WTCCC data.

  20722033   The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.

  20808825   Novel association strategy with copy number variation for identifying new risk Loci of human diseases.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  21036813   A variable selection method for genome-wide association studies.

  21152001   The association of 1q32 and STAT3 variants with ankylosing spondylitis suggests genetic overlap with Crohn's disease.

  21211616   Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records.

  21217814   Presymptomatic risk assessment for chronic non-communicable diseases.

  21270278   An interferon-induced helicase (IFIH1) gene polymorphism associates with different rates of progression from autoimmunity to type 1 diabetes.

  21570397   Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.

  21622953   ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework.

  21926296   Experimental designs for robust detection of effects in genome-wide case-control studies.

  22110093   Cesarean section and interferon-induced helicase gene polymorphisms combine to increase childhood type 1 diabetes risk.

  22140419   BLOCK-BASED BAYESIAN EPISTASIS ASSOCIATION MAPPING WITH APPLICATION TO WTCCC TYPE 1 DIABETES DATA.

  22493691   Novel associations for hypothyroidism include known autoimmune risk loci.

  22496761   Improving power of genome-wide association studies with weighted false discovery rate control and prioritized subset analysis.

  22554139   Ultrahigh-dimensional variable selection method for whole-genome gene-gene interaction analysis.

  22661644   Genetic markers of rheumatoid arthritis susceptibility in anti-citrullinated peptide antibody negative patients.

  23095127   Bag of Naïve Bayes: biomarker selection and classification from genome-wide SNP data.

  24449572   Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

  24988487   Coherent somatic mutation in autoimmune disease.

  25061809   Analyzing genome-wide association studies with an FDR controlling modification of the Bayesian Information Criterion.

  25652333   Genetics of serum concentration of IL-6 and TNFα in systemic lupus erythematosus and rheumatoid arthritis: a candidate gene analysis.

  25829454   Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes.

  27109064   Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis.

  27109359   Identifying genetically driven clinical phenotypes using linear mixed models.

  27153677   Assessing statistical significance in multivariable genome wide association analysis.

  27156530   Genetic variation in IBD: progress, clues to pathogenesis and possible clinical utility.

  27716086   Association of CD247 (CD3ζ) gene polymorphisms with T1D and AITD in the population of northern Sweden.

  27892471   Combining Multiple Hypothesis Testing with Machine Learning Increases the Statistical Power of Genome-wide Association Studies.

  28603863   Identification of PTPN22, ST6GAL1 and JAZF1 as psoriasis risk genes demonstrates shared pathogenesis between psoriasis and diabetes.

  29954342   LPG: A four-group probabilistic approach to leveraging pleiotropy in genome-wide association studies.

  30845666   Cannabinoid Signaling in the Skin: Therapeutic Potential of the "C(ut)annabinoid" System.

  30888520   Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.

  34145262   Genome-wide association study identifies five risk loci for pernicious anemia.

  34521982   Identifying the lungs as a susceptible site for allele-specific regulatory changes associated with type 1 diabetes risk.