SNP information rs2274976

Research and publications:

  17697348   Technology to accelerate pangenomic scanning for unknown point mutations in exonic sequences: cycling temperature capillary electrophoresis (CTCE)

  18191955   Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools

  19064578   No association of single nucleotide polymorphisms in one-carbon metabolism genes with prostate cancer risk

  19190136   Association of thymidylate synthase gene with endometrial cancer risk in a Chinese population

  19421414   Genetic variation in the methylenetetrahydrofolate reductase gene, MTHFR, does not influence the risk of visual impairment in Leber hereditary optic neuropathy.

  19493349   118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects

  19591822   Prevalence of genetic thrombophilic polymorphisms in the Sri Lankan population--implications for association study design and clinical genetic testing services

  19683694   Genetic association study of putative functional single nucleotide polymorphisms of genes in folate metabolism and spina bifida

  20031578   Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine ​​in a healthy population: a genome-wide assessment of 13,974 participants in the Women's Genome Health Study.

  20056627   Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry

  20416077   Identification of type 2 diabetes-associated combination of SNPs using support vector machine.

  20458436   Early-onset ischaemic stroke: analysis of 58 polymorphisms in 17 genes involved in methionine metabolism.

  20890936   Maternal polymorphisms in folic acid metabolic genes are associated with nonsyndromic cleft lip and/or palate in the Brazilian population.

  21146954   Genes and abdominal aortic aneurysm

  21254359   Folate pathway and nonsyndromic cleft lip and palate.

  21274745   Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study.

  21343546   Phase II trial of pemetrexed and bevacizumab in patients with recurrent or metastatic head and neck cancer.

  21362212   [Detection of single nucleotide polymorphisms of mthfr and dpyd genes in leukemia cell lines K562 and K562/A02].

  21363880   Phase I trial of pemetrexed in combination with cetuximab and concurrent radiotherapy in patients with head and neck cancer.

  21537397   Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations.

  21992066   Challenges in the association of human single nucleotide polymorphism mentions with unique database identifiers.

  22087200   Polymorphisms of methylenetetrahydrofolate reductase are not a risk factor for Kawasaki disease in the Korean population.

  22241680   Deep sequencing study of the MTHFR gene to identify variants associated with myelomeningocele.

  22281051   Association of factor V gene polymorphism with arteriovenous graft failure.

  22616673   Global tests of P-values for multifactor dimensionality reduction models in selection of optimal number of target genes.

  22933837   A cross-ethnicity investigation of genes previously implicated in primary angle closure glaucoma.

  23227261   Folate metabolism gene 5,10-methylenetetrahydrofolate reductase (MTHFR) is associated with ADHD in myelomeningocele patients.

  23276522   Genetic variation at fifteen gene loci associated with the folate metabolic pathway and the risk of head and neck carcinoma: the Women's Genome Health Study.

  23294634   Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction.

  24033266   A systematic approach to assessing the clinical significance of genetic variants.

  24254627   MTHFR rs2274976 polymorphism is a risk marker for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.

  24853127   Tagging SNPs in the MTHFR gene and risk of ischemic stroke in a Chinese population.

  25129243   Significant association of MTHFD1 1958G>A single nucleotide polymorphism with nonsyndromic cleft lip and palate in Indian population.

  25218601   Epistasis between polymorphisms in COMT, ESR1, and GCH1 influences COMT enzyme activity and pain.

  26834978   Is MTHFD1 polymorphism rs 2236225 (c.1958G>A) associated with the susceptibility of NSCL/P? A systematic review and meta-analysis.

  27783031   Association of MTHFR, SLC19A1 Genetic Polymorphism, Serum Folate, Vitamin B(12) and Hcy Status with Cognitive Functions in Chinese Adults.

  30884202   Association study between genetic polymorphisms in folate metabolism and gastric cancer susceptibility in Chinese Han population: A case-control study.

  31005971   The MTHFR 677C>T polymorphism is associated with unmetabolized folic acid in breast milk in a cohort of Canadian women.

  32117640   Single nucleotide polymorphism of MTHFR rs1801133 associated with elevated Hcy levels affects susceptibility to cerebral small vessel disease.

  32617779   Machine learning in prediction of genetic risk of nonsyndromic oral clefts in the Brazilian population.

  32682401   Association of ESR1 (rs2234693 and rs9340799), CETP (rs708272), MTHFR (rs1801133 and rs2274976) and MS (rs185087) polymorphisms with Coronary Artery Disease (CAD).

  33964857   Genetic variants modify the associations of concentrations of methylmalonic acid, vitamin B-12, vitamin B-6, and folate with bone mineral density.

  34062203   Variation in biomarker levels of metals, persistent organic pollutants, and omega-3 fatty acids in association with genetic polymorphisms among Inuit in Nunavik, Canada.

  34126931   Association analysis of maternal MTHFR gene polymorphisms and the occurrence of congenital heart disease in offspring.

  35030476   Associations between AGT, MTHFR, and VEGF gene polymorphisms and preeclampsia in the Chinese population.

  35057543   Associations between Serum Betaine, Methyl-Metabolizing Genetic Polymorphisms and Risk of Incident Type 2 Diabetes: A Prospective Cohort Study in Community-Dwelling Chinese Adults.

  35332781   Folate metabolism abnormalities in infertile patients with endometriosis.