Vitamin b2 mthfr
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Vitamin B2, also known as riboflavin, is a vital nutrient necessary for human health and is part of the group of eight B vitamins. Maintaining healthy skin relies on the adequate intake of all B vitamins. Being water-soluble, vitamin B2 can be easily excreted from the body. As the body stores only a small amount of riboflavin, it's essential to include it in your daily diet to meet your nutritional needs. The MTHFR gene encodes an enzyme known as methylenetetrahydrofolate reductase, which plays a crucial role in the methylation cycle. This enzyme converts 5,10-methylene TetraHydroFolate (THF) into 5-methyl THF, a necessary step for converting homocysteine into methionine.
Moreover, MTHFR is involved in the conversion of folate to S-adenosylmethionine (SAMe), which serves as a universal donor for methylation in DNA. The methylation cycle is vital for numerous bodily functions.
Vitamin B2, alongside Vitamin B1, participates in homocysteine metabolism. Deficiency in Vitamin B2 can lead to elevated levels of homocysteine, an amino acid with harmful effects.
rs1801133, also known as C677T, is a single nucleotide polymorphism (SNP) located in the MTFHR gene. The presence of the T allele in rs1801133 reduces enzyme activity, resulting in a decreased efficiency of folate processing, leading to elevated homocysteine levels in the body.
Follow the link of the selected polymorphism to read a brief description of how the selected polymorphism affects Vitamin B2 (riboflavin) and see a list of existing studies.
SNP polymorphisms related to the topic Vitamin B2 (riboflavin):
| rs346822 | |
| rs2929859 | |
| rs16852179 | |
| rs4494951 | |
| rs6054605 | |
| rs910857 | |
| rs3746807 | |
| rs3746802 | |
| rs3746804 | |
| rs34499319 | |
About The Author
Li Dali
Li Dali, a National Foundation for Outstanding Youth Fund recipient, is a researcher at the School of Life Sciences in East China Normal University. He earned his PhD in genetics from Hunan Normal University in 2007 and conducted collaborative research at Texas A&M University during his doctoral studies. Li Dali and his team have optimized and innovated gene editing technology, leading to the establishment of a world-class system for constructing gene editing disease models. Choline (vitaman B4) is a vital nutrient often lacking in many diets. Indeed, a large portion of... Vitamin B5, also known as pantothenic acid, naturally occurs in various plants and animals,... Vitamin E is widely acknowledged for its crucial role in shielding cell components from oxidative...
