SNP information rs964184

Research and publications:

  19060906   Common variants at 30 loci contribute to polygenic dyslipidemia.

  19656773   A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.

  19951432   Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease

  20037589   A genome-wide perspective of genetic variation in human metabolism

  20160193   Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.

  20339536   Genome-wide association of lipid-lowering response to statins in combined study populations.

  20385826   Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC).

  20421590   Genetic causes of high and low serum HDL-cholesterol.

  20434130   Interpretation of association signals and identification of causal variants from genome-wide association studies.

  20571505   A single nucleotide polymorphism in APOA5 determines triglyceride levels in Hong Kong and Guangzhou Chinese.

  20657596   Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.

  20838585   Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.

  20839009   Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica.

  20844574   An immune response network associated with blood lipid levels.

  20864672   Genetic variants influencing circulating lipid levels and risk of coronary artery disease.

  20876667   Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

  21041806   Genetic determinants of plasma triglycerides.

  21378990   Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

  21527746   Triglycerides and heart disease: still a hypothesis?

  21589926   Knowledge-driven multi-locus analysis reveals gene-gene interactions influencing HDL cholesterol level in two independent EMR-linked biobanks.

  21597005   An increased burden of common and rare lipid-associated risk alleles contributes to the phenotypic spectrum of hypertriglyceridemia.

  21673312   Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

  21676895   A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium.

  21729881   Genome-wide association study identifies common variants associated with circulating vitamin E levels.

  21738485   Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.

  21860704   Implications of discoveries from genome-wide association studies in current cardiovascular practice.

  21875899   Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour.

  21880794   Hyperlipoproteinemia type 1 and recurrent acute pancreatitis caused by antibodies to lipoprotein lipase in a young girl with Sjögren's syndrome.

  21889769   Variants in the APOA5 gene region and the response to combination therapy with statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia.

  22003152   Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.

  22022282   A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains.

  22073310   Association of genetic loci with blood lipids in the Chinese population.

  22315312   Genetic predisposition to dyslipidemia and type 2 diabetes risk in two prospective cohorts.

  22359512   Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

  22399527   Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

  22425169   Vitamin D dependent effects of APOA5 polymorphisms on HDL cholesterol.

  22437554   Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.

  22546499   Genome-wide association studies with metabolomics

  22567092   MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS.

  22588700   Genetics of coronary artery disease in the 21st century.

  22590636   Prevalence and determinants of metabolic syndrome among women in Chinese rural areas.

  22623978   A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides.

  22914552   APOA5 genotype modulates 2-y changes in lipid profile in response to weight-loss diet intervention: the Pounds Lost Trial.

  22972380   Investigation of genetic risk factors for chronic adult diseases for association with preterm birth

  22988944   Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases.

  23119086   Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate.

  23404648   An association study between genetic polymorphisms related to lipoprotein-associated phospholipase A(2) and coronary heart disease.

  23468967   Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies.

  23505323   Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.

  23696881   Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation.

  23832694   Common genetic variants associated with lipid profiles in a Chinese pediatric population.

  24131021   The 11q23.3 genomic region-rs964184-is associated with cardiovascular disease in patients with rheumatoid arthritis.

  24270849   Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data.

  24386469   Using systems biology approaches to analyze genome-wide association studies of myocardial infarction and blood cholesterol in the Nurses' Health Study and the Health Workers Follow-up Study.

  24623848   Genetic variants reflecting higher vitamin e status in men are associated with reduced risk of prostate cancer.

  24740359   Mapping the genetic architecture of gene regulation in whole blood.

  24759732   Genetic polymorphism of cytochrome P450 4F2, vitamin E level and histological response in adults and children with nonalcoholic fatty liver disease who participated in PIVENS and TONIC clinical trials.

  24768220   Genetic and environmental determinants of the susceptibility of Amerindian derived populations for having hypertriglyceridemia.

  24879641   Inheritance of rare functional GCKR variants and their contribution to triglyceride levels in families.

  24886709   Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.

  24922540   Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study.

  24931982   GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database.

  24932356   Genetics of coronary artery disease: an update.

  24932782   Genetic risk score and adiposity interact to influence triglyceride levels in a cohort of Filipino women.

  24979386   Rs964184 (APOA5-A4-C3-A1) is related to elevated plasma triglyceride levels, but not to an increased risk for vascular events in patients with clinically manifest vascular disease.

  24991929   Association of common genetic variants with lipid traits in the Indian population.

  25050552   A systematic evaluation of short tandem repeats in lipid candidate genes: riding on the SNP-wave.

  25469254   Association of a genetic variant of the ZPR1 zinc finger gene with type 2 diabetes mellitus.

  25542012   Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.

  26238946   Association of genetic variants with dyslipidemia.

  26256467   Genome-wide association study of triglyceride response to a high-fat meal among participants of the NHLBI Genetics of Lipid Lowering Drugs and Diet Network (GOLDN).

  26397108   Effects of Polymorphisms in APOA4-APOA5-ZNF259-BUD13 Gene Cluster on Plasma Levels of Triglycerides and Risk of Coronary Heart Disease in a Chinese Han Population.

  26405538   Association of FURIN and ZPR1 polymorphisms with metabolic syndrome.

  26445370   Genetic Effects on Longitudinal Changes from Healthy to Adverse Weight and Metabolic Status – The HUNT Study.

  26634697   Multiple susceptibility loci at chromosome 11q23.3 are associated with plasma triglyceride in East Asians.

  26776183   INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

  26780889   Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

  26789557   Common genetic variants and subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA).

  26847647   Experimental Biology for the Identification of Causal Pathways in Atherosclerosis.

  26885234   Association study of BUD13-ZNF259 gene rs964184 polymorphism and hemorrhagic stroke risk.

  26892960   From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.

  26958643   Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.

  26981194   Complexity of vitamin E metabolism.

  27189168   The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease.

  27257688   Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.

  27294088   Genetics of the acute coronary syndrome.

  27312935   Genetics of Insulin Resistance and the Metabolic Syndrome.

  27350042   Blood lipids influence DNA methylation in circulating cells.

  27386434   Zinc Finger 259 Gene Polymorphism rs964184 is Associated with Serum Triglyceride Levels and Metabolic Syndrome.

  27411854   Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes.

  27424552   Genomics era and complex disorders: Implications of GWAS with special reference to coronary artery disease, type 2 diabetes mellitus, and cancers.

  27453504   An exome array study of the plasma metabolome.

  27655946   Incorporating Functional Annotations for Fine-Mapping Causal Variants in a Bayesian Framework Using Summary Statistics.

  28138111   Association of CDKN2B-AS1 rs1333049 with Brain Diseases: A Case-control Study and a Meta-analysis.

  28209224   Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

  28245265   Admixture mapping in two Mexican samples identifies significant associations of locus ancestry with triglyceride levels in the BUD13/ZNF259/APOA5 region and fine mapping points to rs964184 as the main driver of the association signal.

  28426714   A genetic risk score for CAD, psychological stress, and their interaction as predictors of CAD, fatal MI, non-fatal MI and cardiovascular death.

  28577571   Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

  28610615   Quantitative trait loci at the 11q23.3 chromosomal region related to dyslipidemia in the population of Andhra Pradesh, India.

  28666712   The association between six genetic variants and blood lipid levels in pregnant Chinese Han women.