Normal allele: GG
Missense LRRK2 variant is a risk factor for Parkinson's disease.
Polymorphism rs78365431 is related to topics like this:
Research and publications:
18973807 Focus on pathogenetic mechanisms associated with LRRK2 in Parkinson's disease.
20301387 LRRK2 Parkinson Disease.
21632271 Lrrk2 p.Q1111H substitution and Parkinson's disease in Latin America.
21661047 Genome-wide linkage study of LRRK2-related Parkinson's disease modifiers.
21885347 Association of LRRK2 exonic variants with Parkinson's disease susceptibility: a case-control study.
24488318 Structural and functional in silico analysis of LRRK2 missense substitutions.