SNP information rs75932628

Research and publications:

  23380991   TREM2 R47H variant as a risk factor for early-onset Alzheimer's disease.

  23391427   TREM2 is associated with risk of Alzheimer's disease in the Spanish population.

  23510020   Have we learned everything we need to know from genetic research: Is genetics over for Alzheimer's disease?

  23582655   Variants of activation of the receptor expressed on myeloid cells 2 are associated with both the behavioral variant of frontotemporal lobar degeneration and Alzheimer's disease.

  23759145   TREM2 mutations are rare in a French cohort of patients with frontotemporal dementia.

  23800361   TREM2 in neurodegeneration: evidence linking the p.R47H variant to frontotemporal dementia and Parkinson's disease.

  23855982   Assessing the association of TREM2 rs75932628 with Alzheimer's disease in a population-based sample: the Cache County Study.

  24041969   Assessing the role of the TREM2 p.R47H variant as a risk factor for Alzheimer's disease and frontotemporal dementia.

  24184202   Triggering receptor expressed on myeloid cell variant 2 is rare in late-onset Alzheimer's disease in Han Chinese.

  24378087   Study of trigger receptor expressed on variant 2 myeloid cells in the Wisconsin Alzheimer's Disease Prevention Registry.

  24443964   Review: Genetics of Alzheimer's disease;

  24535663   TREM2 variant p.R47H as a risk factor for sporadic amyotrophic lateral sclerosis.

  24602511   Trigger receptor expressed on myeloid cells 2 is rare in Parkinson's disease in a Han Chinese cohort.

  24663666   Evidence of the trem2 variant is associated with a triple risk of Alzheimer's disease.

  24725293   Study of the association of TREM2 rs75932628 polymorphism with late-onset Alzheimer's disease in a Chinese Han population.

  24899047   TREM2 coding variants increase the risk of Alzheimer's disease.

  25027412   Frontobasal gray matter loss is associated with the TREM2 p.R47H variant.

  25108264   Genomics in neurological disorders.

  25186855   The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.

  25186950   Changes in TREM2 protein expression correlate with neurodegenerative pathologies of Alzheimer's disease in postmortem temporal cortex.

  25260849   TREM2 analysis and increased risk of Alzheimer's disease.

  25426068   Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible link.

  25585992   TREM2 R47H variant and risk of essential tremor: a cross-sectional international multicenter study.

  25741868   Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.

  25852195   Lack of genetic association between TREM2 and Alzheimer's disease in East Asian populations: a systematic review and meta-analysis.

  26026943   Assessment of TREM2 rs75932628 association with amyotrophic lateral sclerosis in a Chinese population.

  26037549   TREM2 variants and risk of Alzheimer's disease: a meta-analysis.

  26058841   More evidence linking a rare TREM2 mutation (R47H) to Alzheimer's disease risk.

  26058955   Assessing the association of TREM2 rs75932628 with Parkinson's disease and multiple system atrophy in a Chinese population.

  26365049   Convergent sets of genetic and expression data highlight the susceptibility of TREM2 to Parkinson's disease.

  26438529   Genetics draws attention to microglial inflammation in Alzheimer's disease.

  26680604   Polygenic analysis of late-onset Alzheimer's disease in mainland China.

  26704436   Genetic analysis of TREM2 variants in Chinese Han patients with sporadic Parkinson's disease.

  26758262   Study of the association of TREM2 rs75932628 polymorphism with leukoaraiosis or Parkinson's disease in the Chinese Han population.

  27051467   TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in the hippocampus in Alzheimer's disease.

  27274215   Genes associated with Alzheimer's disease: review and current status.

  27313629   Modeling Alzheimer's disease using induced pluripotent stem cells: current issues and future challenges.

  27589997   Rare TREM2 variants associated with Alzheimer's disease show reduced cell surface expression.

  27653456   Systematic analysis of genetic variants in Han Chinese patients with sporadic Parkinson's disease.

  28430856   A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK.

  28449691   The impact of rare and low-frequency genetic variants in common disease.

  28650998   Functional annotation of Alzheimer's disease-associated loci identified by GWAS.

  29256968   Lack of association between trigger receptor expressed on myeloid cell 2 polymorphism rs75932628 and late-onset Alzheimer's disease in a Chinese Han population.

  29322490   The rs75932628 and rs2234253 polymorphisms of the TREM2 gene were associated with susceptibility to frontotemporal lobar degeneration in Caucasian populations.

  30109269   Association study between multiple system atrophy and TREM2 p.R47H.

  30222607   The p.R47H Variant of TREM2 Gene is Associated With Late-onset Alzheimer Disease in Colombian Population.

  30705288   A transethnic meta-analysis of rare coding variants PLCG2, ABI3 and TREM2 confirms their common contribution to Alzheimer's disease.

  30883352   TREM2 Variants and Neurodegenerative Diseases: A Systematic Review and Meta-Analysis.

  31362167   TREM2 R47H (rs75932628) variant is unlikely to contribute to Multiple Sclerosis susceptibility and severity in a large Greek MS cohort.

  31513029   Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders.

  31799158   Association of MS4A6A, CD33 and TREM2 gene polymorphisms with late-onset Alzheimer's disease.

  32250197   Evaluation of the association of TREM2 rs75932628 variant with Parkinson's disease in a Greek population and meta-analysis of current data.

  32635934   TREM2 ectodomain and its soluble form in Alzheimer's disease.

  32651314   Whole exome sequencing analysis of Alzheimer's disease in non-APOE*4 carriers.

  33815092   Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.

  34340230   Association between the TREM2 gene and late-onset Alzheimer's disease in the Chinese Han population.

  35003116   Targeting TREM2 in Parkinson's disease: where to go?

  35260199   A neurodegenerative disease landscape of rare mutations in Colombia due to founder effects.

  35864757   TREM2 coding variants in Slovak patients with Alzheimer's disease.