SNP information rs445925

Research and publications:

  20838585   Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.

  21909108   Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.

  21977987   Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses.

  22089642   Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE.

  22159054   A comprehensive genetic association study of Alzheimer disease in African Americans.

  22368281   Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a).

  22530058   Evidence of differential allelic effects between adolescents and adults for plasma high-density lipoprotein.

  23092954   SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits

  23696881   Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation.

  24386469   Using systems biology approaches to analyze genome-wide association studies of myocardial infarction and blood cholesterol in the Nurses' Health Study and the Health Workers Follow-up Study.

  26520901   Impact of carotid atherosclerosis loci on cardiovascular events.

  26686871   Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies.

  26690388   Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.

  26754576   The rs5888 single nucleotide polymorphism in scavenger receptor class B type 1 (SCARB1) gene and the risk of premature coronary artery disease: a case-control study.

  26776183   INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

  26892960   From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.

  26950853   Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium.

  26958643   Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.

  27585988   Structured sparse CCA for brain imaging genetics via graph OSCAR.

  27775101   Incorporating Concomitant Medications into Genome-Wide Analyses for the Study of Complex Disease and Drug Response.

  28209224   Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

  28371326   Susceptibility loci for metabolic syndrome and metabolic components identified in Han Chinese: a multi-stage genome-wide association study.

  29695241   Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.

  29712557   Association of apolipoprotein E gene polymorphisms with blood lipids and their interaction with dietary factors.

  34241534   Multiethnic Genome-Wide Association Study of Subclinical Atherosclerosis in Individuals With Type 2 Diabetes.

  34677008   Low Lipoprotein(a) Levels Predict Hepatic Fibrosis in Patients With Nonalcoholic Fatty Liver Disease.

  34905955   Pharmacogenetic loci for rosuvastatin are associated with intima-media thickness change and coronary artery disease risk.

  35387194   Personalized Dietary Recommendations Based on Lipid-Related Genetic Variants: A Systematic Review.