Normal allele: TT
Mutations in the LRRK2 gene cause autosomal dominant parkinsonism with onset at an older age and good response to levodopa therapy.
Polymorphism rs35870237 is related to topics like this:
Research and publications:
15541309 Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
15880653 An LRRK2 mutation as a cause for the parkinsonism in the original PARK8 family.
16321986 The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity.
20301387 LRRK2 Parkinson Disease.
21885347 Association of LRRK2 exonic variants with Parkinson's disease susceptibility: a case-control study.