Normal allele: CC
A single SNCA rs356220 polymorphism is directly associated with Parkinson's disease and plasma alpha-synuclein levels.
Polymorphism rs356220 is related to topics like this:
Research and publications:
15637659 Linkage disequilibrium patterns and tagSNP transferability among European populations.
19771175 Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.
21060011 SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.
22086882 No association between Parkinson disease alleles and the risk of melanoma.
24514572 Association of Parkinson disease risk loci with mild parkinsonian signs in older persons.
26773131 FINEMAP: efficient variable selection using summary data from genome-wide association studies.
21425343 Replication of MAPT and SNCA, but not PARK16-18, as Parkinson's disease susceptibility genes.
26942037 Genetic profile, environmental exposures and their interactions in Parkinson's disease.
22425546 SNCA polymorphisms, smoking, and sporadic Parkinson's disease in Japanese people.
22839974 The UCHL1 S18Y variant is a risk factor for Parkinson's disease in Japan.
31863812 Association between SNCA rs356220 polymorphism and Parkinson's disease: a meta-analysis.