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SNP information rs356220

RS356220

Normal allele: CC

A single SNCA rs356220 polymorphism is directly associated with Parkinson's disease and plasma alpha-synuclein levels.

Polymorphism rs356220 is related to topics like this:

Parkinson is a genetic disease

A disorder that progresses gradually within the nervous system is known as Parkinson's disease. It...


Research and publications:

  15637659   Linkage disequilibrium patterns and tagSNP transferability among European populations.

  19771175   Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.

  20070850   Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.

  21060011   SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.

  22086882   No association between Parkinson disease alleles and the risk of melanoma.

  24514572   Association of Parkinson disease risk loci with mild parkinsonian signs in older persons.

  26773131   FINEMAP: efficient variable selection using summary data from genome-wide association studies.

  29652634   Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.

  31189032   Dementia with lewy bodies: GBA1 mutations are associated with cerebrospinal fluid alpha-synuclein profile.

  20711177   Common genetic variations in the HLA region are associated with sporadic late-onset Parkinson's disease.

  21425343   Replication of MAPT and SNCA, but not PARK16-18, as Parkinson's disease susceptibility genes.

  21738487   Genome-wide internet-based association study identifies two new loci and a significant genetic component of Parkinson's disease.

  21812969   Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.

  21876681   A genome-wide gene environment study identifies the glutamate receptor gene GRIN2A as a modifier gene for Parkinson's disease through interaction with coffee.

  22892372   Using genome-wide integrated trait analysis to quantify “missing heritability” in Parkinson's disease.

  28927418   A systematic review and integrative approach to decipher the overall molecular link between levodopa response and Parkinson's disease.

  26208350   SNCA genetic variants are associated with susceptibility to Parkinson's disease but not to amyotrophic lateral sclerosis or multiple system atrophy in a Chinese population.

  26732583   Analysis of the association between SNCA, HUSEYO and CSMD1 gene variants and Parkinson's disease in an Iranian population.

  26942037   Genetic profile, environmental exposures and their interactions in Parkinson's disease.

  30410434   Comprehensive analysis of the relationship between SNCA polymorphisms and the risk of Parkinson's disease.

  22425546   SNCA polymorphisms, smoking, and sporadic Parkinson's disease in Japanese people.

  22839974   The UCHL1 S18Y variant is a risk factor for Parkinson's disease in Japan.

  24511991   Identification of a novel Parkinson's disease locus using a stratified genome-wide association study.

  25129240   SNCA variants rs2736990 and rs356220 as risk factors for Parkinson's disease but not amyotrophic lateral sclerosis and multiple system atrophy in a Chinese population.

  27699750   Frequency of single nucleotide polymorphisms and alpha-synuclein haplotypes associated with sporadic Parkinson's disease in a Mexican population.

  31681140   Genetic and environmental factors contributing to the development of Parkinson's disease: a case-control study in the Cypriot population.

  31863812   Association between SNCA rs356220 polymorphism and Parkinson's disease: a meta-analysis.

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