Normal allele: AA
SNCA rs2736990 variants are associated with a twofold increased likelihood of Parkinson's disease.
Polymorphism rs2736990 is related to topics like this:
Research and publications:
15637659 Linkage disequilibrium patterns and tagSNP transferability among European populations.
21060011 SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.
21248740 Genome-wide association study confirms extant PD risk loci among the Dutch.
22025277 Genetic variants of α-synuclein are not associated with essential tremor.
22086882 No association between Parkinson disease alleles and the risk of melanoma.
22912757 Evaluation of the role of SNCA variants in survival without neurological disease.
27628759 Transcriptional Dynamics at Brain Enhancers: from Functional Specialization to Neurodegeneration.
19915575 Genome-wide association study identifies genetic risk underlying Parkinson's disease.
21425343 Replication of MAPT and SNCA, but not PARK16-18, as Parkinson's disease susceptibility genes.
20961626 β-Synuclein and dopamine at the crossroads of Parkinson's disease.
21058943 Replication of GWAS associations for GAK and MAPT in Parkinson's disease.
21412835 Common variants in the PARK and related genes loci and Parkinson's disease.
24868370 Human genetic variation and Parkinson's disease.
22425546 SNCA polymorphisms, smoking, and sporadic Parkinson's disease in Japanese people.
22839974 The UCHL1 S18Y variant is a risk factor for Parkinson's disease in Japan.
28844730 Association between SNCA rs2736990 polymorphism and Parkinson's disease: a meta-analysis.