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SNP information rs2736990

RS2736990

Normal allele: AA

SNCA rs2736990 variants are associated with a twofold increased likelihood of Parkinson's disease.

Polymorphism rs2736990 is related to topics like this:

Parkinson is a genetic disease

A disorder that progresses gradually within the nervous system is known as Parkinson's disease. It...


Research and publications:

  15637659   Linkage disequilibrium patterns and tagSNP transferability among European populations.

  20070850   Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.

  21060011   SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.

  21248740   Genome-wide association study confirms extant PD risk loci among the Dutch.

  21498636   Genome-wide "pleiotropy scan" identifies HNF1A region as a novel pancreatic cancer susceptibility locus.

  21953863   Association of SNCA with Parkinson: replication in the Harvard NeuroDiscovery Center Biomarker Study.

  22025277   Genetic variants of α-synuclein are not associated with essential tremor.

  22086882   No association between Parkinson disease alleles and the risk of melanoma.

  22912757   Evaluation of the role of SNCA variants in survival without neurological disease.

  27628759   Transcriptional Dynamics at Brain Enhancers: from Functional Specialization to Neurodegeneration.

  19915575   Genome-wide association study identifies genetic risk underlying Parkinson's disease.

  21425343   Replication of MAPT and SNCA, but not PARK16-18, as Parkinson's disease susceptibility genes.

  28927418   A systematic review and integrative approach to decipher the overall molecular link between levodopa response and Parkinson's disease.

  20961626   β-Synuclein and dopamine at the crossroads of Parkinson's disease.

  21058943   Replication of GWAS associations for GAK and MAPT in Parkinson's disease.

  21412835   Common variants in the PARK and related genes loci and Parkinson's disease.

  24868370   Human genetic variation and Parkinson's disease.

  26208350   SNCA genetic variants are associated with susceptibility to Parkinson's disease but not to amyotrophic lateral sclerosis or multiple system atrophy in a Chinese population.

  28676755   SNCA gene variants are associated with Parkinson's disease risk and cognitive symptoms in a Brazilian sample.

  30410434   Comprehensive analysis of the relationship between SNCA polymorphisms and the risk of Parkinson's disease.

  22425546   SNCA polymorphisms, smoking, and sporadic Parkinson's disease in Japanese people.

  22839974   The UCHL1 S18Y variant is a risk factor for Parkinson's disease in Japan.

  25129240   SNCA variants rs2736990 and rs356220 as risk factors for Parkinson's disease but not amyotrophic lateral sclerosis and multiple system atrophy in a Chinese population.

  27699750   Frequency of single nucleotide polymorphisms and alpha-synuclein haplotypes associated with sporadic Parkinson's disease in a Mexican population.

  28844730   Association between SNCA rs2736990 polymorphism and Parkinson's disease: a meta-analysis.

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