SNP information rs2292239

Research and publications:

  17554260   Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

  18252225   On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants.

  18423522   Estimating odds ratios in genome scans: an approximate conditional likelihood approach

  18462017   Mapping the genetic architecture of gene expression in human liver.

  18556337   Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1)

  18853133   Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

  18987646   The expanding genetic overlap between multiple sclerosis and type I diabetes.

  19061490   FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease.

  19073967   Shared and distinct genetic variants in type 1 diabetes and celiac disease

  19140132   Unbiased estimation of odds ratios: combining genomewide association scans with replication studies.

  19359276   Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes.

  19430480   Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

  19639606   Correcting the “winner's curse” in odds ratios based on genome-wide association results for major complex human diseases.

  19951419   Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis.

  20351726   Whole-genome association mapping of gene expression in the human prefrontal cortex.

  20549515   Genome-wide searching of rare genetic variants in WTCCC data.

  20587799   Genetics of type 1 diabetes: what next?

  20647273   Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.

  20668683   Genetically dependent ERBB3 expression modulates antigen presenting cell function and type 1 diabetes risk.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20885991   Advances and challenges in biomarker development for type 1 diabetes prediction and prevention using omic technologies.

  21129726   Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals.

  21266329   Tests for genetic interactions in type 1 diabetes: linkage and stratification analyses of 4,422 affected sib-pairs.

  21270831   Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population.

  21559886   Polymorphisms in chromosome region 12q13 and their influence on age at onset of type 1 diabetes.

  21826374   Selective IgA deficiency in autoimmune diseases.

  21829393   Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

  21850031   Evidence for two independent associations with type 1 diabetes at the 12q13 locus.

  21873553   Genetic analysis of adult-onset autoimmune diabetes.

  25422107   Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study.

  25530448   Evidence of ERBB3 gene association with rheumatoid arthritis predisposition.

  26019233   Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci†.

  26245339   Polymorphisms in the CTSH gene may influence the progression of diabetic retinopathy: a candidate-gene study in the Danish Cohort of Pediatric Diabetes 1987 (DCPD1987).

  26320593   A single-nucleotide polymorphism of CCL21 rs951005 T>C is associated with susceptibility of polymyositis and such patients with interstitial lung disease in a Chinese Han population.

  26450151   The genetic and regulatory architecture of ERBB3-type 1 diabetes susceptibility locus.

  26904692   Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control.

  27331016   ERBB3-rs2292239 as primary type 1 diabetes association locus among non-HLA genes in Chinese.

  27730450   Candidate gene studies of diabetic retinopathy in human.

  27777593   Genetic and epigenetic studies of atopic dermatitis.

  28646072   Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study.

  28738846   Long non-coding RNAs as novel players in β cell function and type 1 diabetes.

  29109006   The rs2292239 polymorphism in ERBB3 gene is associated with risk for type 1 diabetes mellitus in a Brazilian population.

  30888520   Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.

  31467911   The Association between rs2292239 Polymorphism in ERBB3 Gene and Type 1 Diabetes: A Meta-Analysis.

  31808541   Type 1 diabetes linked PTPN22 gene polymorphism is associated with the frequency of circulating regulatory T cells.

  31976761   Associations of rs2300782 CAMK4, rs2292239 ERBB3 and rs10491034 ARHGAP22 with Diabetic Retinopathy Among Chinese Hui Population.

  34448034   Genetic variation at ERBB3/IKZF4 and sexual dimorphism in epitope spreading in single autoantibody-positive relatives.