SNP information rs965513

Research and publications:

  19198613   Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.

  19730683   The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

  20350937   The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.

  20505153   A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

  20585100   Genome-wide association studies of cancer.

  20628519   Genetic Predisposition to Familial Nonmedullary Thyroid Cancer: An Update of Molecular Findings and State-of-the-Art Studies.

  21730105   The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population.

  21858135   Efficient replication of over 180 genetic associations with self-reported medical data.

  21981779   Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies.

  22267200   Discovery of common variants associated with low TSH levels and thyroid cancer risk.

  22282540   Thyroid cancer susceptibility polymorphisms: confirmation of loci on chromosomes 9q22 and 14q13, validation of a recessive 8q24 locus and failure to replicate a locus on 5q24

  22493691   Novel associations for hypothyroidism include known autoimmune risk loci.

  22586128   The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type.

  22882326   FOXE1 polymorphisms are associated with familial and sporadic nonmedullary thyroid cancer susceptibility.

  23244446   Applying semantic web technologies for phenome-wide scan using an electronic health record linked Biobank.

  23327367   Patterns of FOXE1 expression in papillary thyroid carcinoma by immunohistochemistry.

  23344678   Genetic associations with neonatal thyroid-stimulating hormone levels.

  23408906   A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.

  23847140   Confirmation of papillary thyroid cancer susceptibility loci identified by genome-wide association studies of chromosomes 14q13, 9q22, 2q35 and 8p12 in a Chinese population.

  24144365   Familial multinodular goiter syndrome with papillary thyroid carcinomas: mutational analysis of the associated genes in 5 cases from 1 Chinese family.

  24591304   Significant SNPs have limited prediction ability for thyroid cancer.

  24723258   Associations between rs965513/rs944289 and papillary thyroid carcinoma risk: a meta-analysis.

  24744143   Common genetic variants on FOXE1 contributes to thyroid cancer susceptibility: evidence based on 16 studies.

  24756757   Relationships of FOXE1 and ATM genetic polymorphisms with papillary thyroid carcinoma risk: a meta-analysis.

  25303483   Genetic predisposition to papillary thyroid carcinoma: involvement of FOXE1, TSHR, and a novel lincRNA gene, PTCSC2.

  25436638   Genetic variants associated with serum thyroid stimulating hormone (TSH) levels in European Americans and African Americans from the eMERGE Network.

  25562676   The common genetic variant rs944289 on chromosome 14q13.3 associates with risk of both malignant and benign thyroid tumors in the Japanese population.

  25743335   Whole-genome sequence-based analysis of thyroid function.

  25849217   Common variants at 9q22.33, 14q13.3, and ATM loci, and risk of differentiated thyroid cancer in the French Polynesian population.

  25918370   Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer.

  26206751   TITF1 and TITF2 loci variants indicate significant associations with thyroid cancer.

  26356687   Replication and Meta-Analysis of Common Gene Mutations in TTF1 and TTF2 with Papillary Thyroid Cancer.

  26490305   Association between GWAS-Derived rs966423 Genetic Variant and Overall Mortality in Patients with Differentiated Thyroid Cancer.

  26776183   INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

  26991144   Fine-mapping of two differentiated thyroid carcinoma susceptibility loci at 9q22.33 and 14q13.3 detects novel candidate functional SNPs in Europeans from metropolitan France and Melanesians from New Caledonia.

  27079684   Genome-wide association studies and epigenome-wide association studies go together in cancer control.

  27109359   Identifying genetically driven clinical phenotypes using linear mixed models.

  27342578   Papillary Thyroid Carcinoma: Association Between Germline DNA Variant Markers and Clinical Parameters.

  27512836   Clinical features of Hispanic thyroid cancer cases and the role of known genetic variants on disease risk.

  27610545   FOXE1 Polymorphism Interacts with Dietary Iodine Intake in Differentiated Thyroid Cancer Risk in the Cuban Population.

  27824288   Genotype Analyses in the Japanese and Belarusian Populations Reveal Independent Effects of rs965513 and rs1867277 but Do Not Support the Role of FOXE1 Polyalanine Tract Length in Conferring Risk for Papillary Thyroid Carcinoma.

  28049826   MYH9 binds to lncRNA gene PTCSC2 and regulates FOXE1 in the 9q22 thyroid cancer risk locus.

  28499365   Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.

  28660995   Age at diagnosis and gender modify the risk of 9q22 and 14q13 polymorphisms for papillary thyroid carcinoma.

  29788924   Exploration of the association between FOXE1 gene polymorphism and differentiated thyroid cancer: a meta-analysis.

  30089490   Thyroid cancers of follicular origin in a genomic light: in-depth overview of common and unique molecular marker candidates.

  31501191   Genetic Variants Implicate Dual Oxidase-2 in Familial and Sporadic Nonmedullary Thyroid Cancer.

  31681970   Clinical implications of GWAS variants associated with differentiated thyroid cancer.

  32104174   Association of rs944289, rs965513, and rs1443434 in TITF1/TITF2 with Risks of Papillary Thyroid Carcinoma and with Nodular Goiter in Northern Chinese Han Populations.

  33551988   The Contribution of Genetic Variants to the Risk of Papillary Thyroid Carcinoma in the Kazakh Population: Study of Common Single Nucleotide Polymorphisms and Their Clinicopathological Correlations.

  34617949   FOXE1 polymorphisms and chronic exposure to nitrates in drinking water cause metabolic dysfunction, thyroid abnormalities, and genotoxic damage in women.