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SNP information rs944289

RS944289

Normal allele: CC

The FOXE1 locus is a major genetic determinant of radiation-dependent thyroid cancer.

Polymorphism rs944289 is related to topics like this:

Genetic testing for thyroid cancer

Thyroid cancer is a prevalent type of malignancy in the endocrine system. Children who undergo...


Research and publications:

  19198613   Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.

  20350937   The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.

  20505153   A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

  20585100   Genome-wide association studies of cancer.

  20628519   Genetic Predisposition to Familial Nonmedullary Thyroid Cancer: An Update of Molecular Findings and State-of-the-Art Studies.

  21730105   The FOXE1 and NKX2-1 loci are associated with susceptibility to papillary thyroid carcinoma in the Japanese population.

  22282540   Thyroid cancer susceptibility polymorphisms: confirmation of loci on chromosomes 9q22 and 14q13, validation of a recessive 8q24 locus and failure to replicate a locus on 5q24

  22586128   The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type.

  23408906   A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.

  23820649   Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease

  23847140   Confirmation of papillary thyroid cancer susceptibility loci identified by genome-wide association studies of chromosomes 14q13, 9q22, 2q35 and 8p12 in a Chinese population.

  24080187   Genome-wide association study implicates a novel RNA gene, the lincRNA AC068718.1, as a risk factor for post-traumatic stress disorder in women.

  24144365   Familial multinodular goiter syndrome with papillary thyroid carcinomas: mutational analysis of the associated genes in 5 cases from 1 Chinese family.

  24452548   Are the SNPs of NKX2-1 associated with papillary thyroid carcinoma in the Han population of Northern China?

  24591304   Significant SNPs have limited prediction ability for thyroid cancer.

  24723258   Associations between rs965513/rs944289 and papillary thyroid carcinoma risk: a meta-analysis.

  24756757   Relationships of FOXE1 and ATM genetic polymorphisms with papillary thyroid carcinoma risk: a meta-analysis.

  24879036   A polymorphism rs12325489C>T in the lincRNA-ENST00000515084 exon was found to modulate breast cancer risk via GWAS-based association analyses.

  24885522   LincSNP: a database of linking disease-associated SNPs to human large intergenic non-coding RNAs.

  25552255   Common genetic variant on 14q13.3 contributes to thyroid cancer susceptibility: evidence based on 12 studies.

  25562676   The common genetic variant rs944289 on chromosome 14q13.3 associates with risk of both malignant and benign thyroid tumors in the Japanese population.

  25743335   Whole-genome sequence-based analysis of thyroid function.

  25849217   Common variants at 9q22.33, 14q13.3, and ATM loci, and risk of differentiated thyroid cancer in the French Polynesian population.

  26206751   TITF1 and TITF2 loci variants indicate significant associations with thyroid cancer.

  26274343   PTCSC3 Is Involved in Papillary Thyroid Carcinoma Development by Modulating S100A4 Gene Expression.

  26356687   Replication and Meta-Analysis of Common Gene Mutations in TTF1 and TTF2 with Papillary Thyroid Cancer.

  26483964   Genomic Study of Cardiovascular Continuum Comorbidity.

  26490305   Association between GWAS-Derived rs966423 Genetic Variant and Overall Mortality in Patients with Differentiated Thyroid Cancer.

  26776183   INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

  26991144   Fine-mapping of two differentiated thyroid carcinoma susceptibility loci at 9q22.33 and 14q13.3 detects novel candidate functional SNPs in Europeans from metropolitan France and Melanesians from New Caledonia.

  27025970   Identification of PTCSC3 as a Novel Locus for Large-Vessel Ischemic Stroke: A Genome-Wide Association Study.

  27079684   Genome-wide association studies and epigenome-wide association studies go together in cancer control.

  27233618   Long noncoding RNAs in cancer: mechanisms of action and technological advancements.

  27251952   Association of rs6983267 Polymorphism and Thyroid Cancer Susceptibility: A Systematic Review and Meta-Analysis.

  27342578   Papillary Thyroid Carcinoma: Association Between Germline DNA Variant Markers and Clinical Parameters.

  27512836   Clinical features of Hispanic thyroid cancer cases and the role of known genetic variants on disease risk.

  27549736   Onco-lncRNA HOTAIR and its functional genetic variants in papillary thyroid carcinoma.

  28499365   Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.

  28607590   Association between SNPs in Long Non-coding RNAs and the Risk of Female Breast Cancer in a Chinese Population.

  28660995   Age at diagnosis and gender modify the risk of 9q22 and 14q13 polymorphisms for papillary thyroid carcinoma.

  29788924   Exploration of the association between FOXE1 gene polymorphism and differentiated thyroid cancer: a meta-analysis.

  30089490   Thyroid cancers of follicular origin in a genomic light: in-depth overview of common and unique molecular marker candidates.

  30099483   Genome-Wide Association Study Reveals Distinct Genetic Susceptibility of Thyroid Nodules From Thyroid Cancer.

  30350351   Fine mapping of 14q13 reveals novel variants associated with different histological subtypes of papillary thyroid carcinoma.

  31681970   Clinical implications of GWAS variants associated with differentiated thyroid cancer.

  32104174   Association of rs944289, rs965513, and rs1443434 in TITF1/TITF2 with Risks of Papillary Thyroid Carcinoma and with Nodular Goiter in Northern Chinese Han Populations.

  32181690   Association of Long Noncoding RNAs Polymorphisms with the Risk of Esophagogastric Junction Adenocarcinoma: A Three-Center Study of 1063 Cases and 1677 Controls.

  33551988   The Contribution of Genetic Variants to the Risk of Papillary Thyroid Carcinoma in the Kazakh Population: Study of Common Single Nucleotide Polymorphisms and Their Clinicopathological Correlations.

  34950210   Genetic Variants Associated with Thyroid Cancer Risk: Comprehensive Research Synopsis, Meta-Analysis, and Cumulative Epidemiological Evidence.

  35169218   Association between long noncoding RNA rs944289 and rs7990916 polymorphisms and the risk of colorectal cancer in a Chinese population.

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