Normal allele: CC
The FOXE1 locus is a major genetic determinant of radiation-dependent thyroid cancer.
Polymorphism rs944289 is related to topics like this:
Research and publications:
19198613 Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations.
20350937 The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl.
20505153 A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.
20585100 Genome-wide association studies of cancer.
24591304 Significant SNPs have limited prediction ability for thyroid cancer.
24723258 Associations between rs965513/rs944289 and papillary thyroid carcinoma risk: a meta-analysis.
24885522 LincSNP: a database of linking disease-associated SNPs to human large intergenic non-coding RNAs.
25743335 Whole-genome sequence-based analysis of thyroid function.
26206751 TITF1 and TITF2 loci variants indicate significant associations with thyroid cancer.
26274343 PTCSC3 Is Involved in Papillary Thyroid Carcinoma Development by Modulating S100A4 Gene Expression.
26483964 Genomic Study of Cardiovascular Continuum Comorbidity.
27233618 Long noncoding RNAs in cancer: mechanisms of action and technological advancements.
27549736 Onco-lncRNA HOTAIR and its functional genetic variants in papillary thyroid carcinoma.
31681970 Clinical implications of GWAS variants associated with differentiated thyroid cancer.