SNP information rs763361

Research and publications:

  17554260   Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

  18853133   Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

  18971939   CD226 Gly307Ser association with multiple autoimmune diseases.

  18987646   The expanding genetic overlap between multiple sclerosis and type I diabetes.

  19073967   Shared and distinct genetic variants in type 1 diabetes and celiac disease

  19359276   Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes.

  19430480   Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

  19624611   The CD226 gene in susceptibility of type 1 diabetes.

  19865102   Multiple sclerosis susceptibility alleles in African Americans.

  19951419   Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis.

  20072139   Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis.

  20089178   Allelic variants in the PHTF1-PTPN22, C12orf30 and CD226 regions as candidate susceptibility factors for the type 1 diabetes in the Estonian population.

  20112382   Confirmation of an association between rs6822844 at the Il2-Il21 region and multiple autoimmune diseases: evidence of a general susceptibility locus.

  20182566   The genetic aspects of multiple sclerosis.

  20219786   The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.

  20236493   The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis.

  20338887   Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases.

  20362272   Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to come.

  20405052   The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.

  20444755   Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.

  20461788   Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients.

  20498205   Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers.

  20508602   The autoimmune disease-associated KIF5A, CD226 and SH2B3 gene variants confer susceptibility for multiple sclerosis.

  20587799   Genetics of type 1 diabetes: what next?

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20885991   Advances and challenges in biomarker development for type 1 diabetes prediction and prevention using omic technologies.

  20887380   Association of the CD226 single nucleotide polymorphism with systemic lupus erythematosus in the Chinese Han population.

  20933377   Recent findings on genetics of systemic autoimmune diseases.

  20952449   Evaluation of the established non-MHC multiple sclerosis loci in an Indian population.

  21162102   Association of the CD226 Ser(307) variant with systemic sclerosis: evidence of a contribution of costimulation pathways in systemic sclerosis pathogenesis.

  21266329   Tests for genetic interactions in type 1 diabetes: linkage and stratification analyses of 4,422 affected sib-pairs.

  21280076   Aggregation of multiple sclerosis genetic risk variants in multiple and single case families.

  21286723   The CD226 gene in susceptibility of rheumatoid arthritis in the Chinese Han population.

  21521299   The role of the non-synonymous CD226 (DNAX-auxiliary molecule-1) variant (Gly 307Ser) in the pathogenesis of isolated Addison's disease and autoimmune polyendocrinopathy type 2.

  21765104   Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction.

  21826374   Selective IgA deficiency in autoimmune diseases.

  21829393   Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

  21852963   Pervasive sharing of genetic effects in autoimmune disease.

  21873553   Genetic analysis of adult-onset autoimmune diabetes.

  21980299   A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.

  22102179   Genetics of systemic sclerosis: an update.

  22190364   Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

  22302395   Influence of MIF, CD40, and CD226 polymorphisms on risk of rheumatoid arthritis.

  22531499   A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis.

  22536486   Lupus nephritis: an overview of recent findings.

  22577522   Shared HLA Class II in Six Autoimmune Diseases in Latin America: A Meta-Analysis.

  22654554   Immunogenetic mechanisms leading to thyroid autoimmunity: recent advances in identifying susceptibility genes and regions.

  22654555   Genetic basis of Graves' disease.

  22728856   CD226 Gly307Ser association with neuromyelitis optica in Southern Han Chinese.

  22941566   Association between the CD226 rs763361 polymorphism and susceptibility to autoimmune diseases: a meta-analysis.

  23000205   Gene network analysis of small molecules with autoimmune disease associated genes predicts a novel strategy for drug efficacy.

  23073294   CD226 Gly307Ser association with multiple autoimmune diseases: a meta-analysis.

  23262348   Association between two genetic variants of CD226 gene and Cervical Squamous Cell Carcinoma: a case-control study.

  23999715   CD226 rs763361 (Gly307Ser) polymorphism is associated with susceptibility to rheumatoid arthritis in Zahedan, southeast Iran.

  24891767   CD226 rs763361 is associated with the susceptibility to type 1 diabetes and greater frequency of GAD65 autoantibody in a Brazilian cohort.

  25057181   CD226 (DNAM-1) is associated with susceptibility to juvenile idiopathic arthritis.

  25328554   Systemic Sclerosis is a Complex Disease Associated Mainly with Immune Regulatory and Inflammatory Genes.

  25645050   Association between the CTLA-4, CD226, FAS polymorphisms and rheumatoid arthritis susceptibility: a meta-analysis.

  25777745   Recent advances in the genetics of systemic sclerosis: toward biological and clinical significance.

  25980680   Differences in B7 and CD28 family gene expression in the peripheral blood between newly diagnosed young-onset and adult-onset type 1 diabetes patients.

  26106387   Pathogenesis of Systemic Sclerosis.

  26346602   CD226 gene polymorphisms are associated with non-small-cell lung cancer in the Chinese Han population.

  26613086   Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis.

  26808113   High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry.

  26904692   Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control.

  26997879   Genetic Susceptibility to Interstitial Lung Disease Associated with Systemic Sclerosis.

  27108704   Genetic polymorphism of cell adhesion molecules in Behçet's disease in the Chinese Han population.

  27454254   Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015.

  27610404   Evaluation of HLA-G 14 bp Ins/Del and +3142G>C Polymorphism with Susceptibility and Early Disease Activity in Rheumatoid Arthritis.

  27722794   Gene-gene interaction between CD40 and CD226 gene on systemic lupus erythematosus in the Chinese Han population.

  28137889   Genetic variant rs763361 regulates multiple sclerosis CD226 gene expression.

  28262800   The influence of population stratification on genetic markers associated with type 1 diabetes.

  28434122   The status of pulmonary fibrosis in systemic sclerosis is associated with IRF5, STAT4, IRAK1, and CTGF polymorphisms.

  29220498   NKG2C Deletion Is a Risk Factor for Human Cytomegalovirus Viremia and Disease After Lung Transplantation.

  29319370   Association between CD226 polymorphism and soluble levels in rheumatoid arthritis: Relationship with clinical activity.

  29338153   Association Study of CD226 and CD247 Genes Single Nucleotide Polymorphisms in Iranian Patients with Systemic Sclerosis.

  29476163   Genetic predictors of systemic sclerosis-associated interstitial lung disease: a review of recent literature.

  29625966   Identification of ST3AGL4, MFHAS1, CSNK2A2 and CD226 as loci associated with systemic lupus erythematosus (SLE) and evaluation of SLE genetics in drug repositioning.

  29991650   The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4(+) T cells.

  30128676   High-resolution melting curve analysis of polymorphisms within CD58, CD226, HLA-G genes and association with multiple sclerosis susceptibility in a subset of Iranian population: a case-control study.

  30145014   CD226 gene polymorphism (rs763361 C>T) is associated with susceptibility to type 1 diabetes mellitus among Egyptian children.

  30327483   Phenome-wide association studies across large population cohorts support drug target validation.

  30888520   Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.

  31114873   Association of Severe Influenza Virus Infections With CD226 (DNAM-1) Variants.

  31854233   Role of CD226 Rs763361 Polymorphism in Susceptibility to Multiple Autoimmune Diseases.

  31916109   Defining genetic risk factors for scleroderma-associated interstitial lung disease : IRF5 and STAT4 gene variants are associated with scleroderma while STAT4 is protective against scleroderma-associated interstitial lung disease.

  33427622   Anti-tumour necrosis factor-alpha response associated with combined CD226 and HLA-DRB1[*]0404 haplotype in rheumatoid arthritis.

  33469055   Impact of immune checkpoint gene CD155 Ala67Thr and CD226 Gly307Ser polymorphisms on small cell lung cancer clinical outcome.

  33584705   Immune Checkpoint-Related Gene Polymorphisms Are Associated With Primary Immune Thrombocytopenia.

  34977040   Gene-Based Testing of Interactions Using XGBoost in Genome-Wide Association Studies.

  35971920   Human CD4(+) and CD8(+) T lymphocyte subpopulations have significantly different surface expression patterns of CD226 and TIGIT molecules.