SNP information rs6511720

Research and publications:

  18193044   Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.

  18196181   Correction of population stratification in large multi-ethnic association studies

  18714375   Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study.

  18852197   Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants

  19060906   Common variants at 30 loci contribute to polygenic dyslipidemia.

  19060910   Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

  19060911   Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

  19087220   Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study.

  19148283   Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.

  19336475   Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk

  19408013   Strategies and issues in the detection of pathway enrichment in genome-wide association studies

  19435741   Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.

  19656773   A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.

  19729614   Ion mobility analysis of lipoprotein subfractions identifies three independent axes of cardiovascular risk.

  19750184   Genome-wide association studies for atherosclerotic vascular disease and its risk factors.

  19802338   Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replicatio

  19888660   Genetic determinants of serum lipid levels in Chinese subjects: a population-based study in Shanghai, China.

  19919681   Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq.

  19951432   Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease

  20031563   Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study.

  20031591   Association of blood lipids with common DNA sequence variants at 19 genetic loci in the multiethnic United States National Health and Nutrition Examination Survey III.

  20308432   Association analysis of 33 lipoprotein candidate genes in multi-generational families of African ancestry.

  20839009   Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica.

  21292264   Genetic predisposition influences plasma lipids of participants on habitual diet, but not the response to reductions in dietary intake of saturated fatty acids.

  21347282   Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

  21507254   Geographic differences in allele frequencies of susceptibility SNPs for cardiovascular disease.

  21738485   Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.

  21829380   Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability.

  21860704   Implications of discoveries from genome-wide association studies in current cardiovascular practice.

  21862702   Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk.

  21875899   Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour.

  21909108   Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.

  21966275   Large-scale gene-centric analysis identifies novel variants for coronary artery disease.

  21977987   Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses.

  22003152   Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.

  22022282   A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains.

  22530058   Evidence of differential allelic effects between adolescents and adults for plasma high-density lipoprotein.

  22567092   MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS.

  22629316   Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.

  22972380   Investigation of genetic risk factors for chronic adult diseases for association with preterm birth

  23050023   Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.

  23092954   SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits

  23098650   Impact of variants within seven candidate genes on statin treatment efficacy.

  23150898   Evaluation of seven common lipid associated loci in a large Indian sib pair study.

  23236364   Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.

  23404648   An association study between genetic polymorphisms related to lipoprotein-associated phospholipase A(2) and coronary heart disease.

  24270849   Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data.

  24274136   Biobanking across the phenome - at the center of chronic disease research.

  24834361   Update on abdominal aortic aneurysm research: from clinical to genetic studies.

  24900971   Meta-analysis of low density lipoprotein receptor (LDLR) rs2228671 polymorphism and coronary heart disease.

  24922540   Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study.

  24931982   GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database.

  25050552   A systematic evaluation of short tandem repeats in lipid candidate genes: riding on the SNP-wave.

  25552592   Variants for HDL-C, LDL-C, and triglycerides identified from admixture mapping and fine-mapping analysis in African American families.

  25682026   Would raising the total cholesterol diagnostic cut-off from 7.5 mmol/L to 9.3 mmol/L improve detection rate of patients with monogenic familial hypercholesterolaemia?

  25951190   Networks in Coronary Heart Disease Genetics As a Step towards Systems Epidemiology.

  26559855   Genetic and Environmental Effects on the Abdominal Aortic Diameter Development.

  26690388   Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.

  26776183   INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

  26958643   Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.

  27294088   Genetics of the acute coronary syndrome.

  27418160   Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms.

  28059143   Influence of coronary artery disease and subclinical atherosclerosis related polymorphisms on the risk of atherosclerosis in rheumatoid arthritis.

  28339009   Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies.

  28379035   Polygenic hypercholesterolemia: examples of GWAS results and their replication in the Czech-Slavonic population.

  28456096   Identifying low density lipoprotein cholesterol associated variants in the Annexin A2 (ANXA2) gene.

  28539666   Replication and fine-mapping of genetic predictors of lipid traits in African-Americans.

  28577571   Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

  29374275   Usefulness of the genetic risk score to identify phenocopies in families with familial hypercholesterolemia?

  31929604   Association of single nucleotide polymorphisms with dyslipidemia in antiretroviral exposed HIV patients in a Ghanaian population: A case-control study.

  34550115   Obesity-related genetic determinants of stroke.

  34905955   Pharmacogenetic loci for rosuvastatin are associated with intima-media thickness change and coronary artery disease risk.