Normal allele: AA
The polymorphism is associated with reduced levels of vitamin B12 in the blood, this effect may be due to reduced absorption of vitamin B12, such people need additional vitamin B12 supplementation in the form of injections.
Polymorphism rs602662 is related to topics like this:
Research and publications:
18776911 Common variants of FUT2 are associated with plasma vitamin B12 levels.
18997004 Widespread balancing selection and pathogen-driven selection at blood group antigen genes.
19744961 Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.
21115529 Genetics and genomics of human ageing.
21507254 Geographic differences in allele frequencies of susceptibility SNPs for cardiovascular disease.
22025780 FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection.
23201895 Common variant in FUT2 gene is associated with levels of vitamin B(12) in Indian population.
27995393 Genetic determinants of serum vitamin B12 and their relation to body mass index.
28824326 FUT2 genetic variants as predictors of tumor development with hepatocellular carcinoma.
30376117 FUT2 Genetic Variants and Reported Respiratory and Gastrointestinal Illnesses During Infancy.
33170161 Genetic test for the prescription of diets in support of physical activity.
33763108 Whole Genome Interpretation for a Family of Five.
34308116 Genetic factors associated with obesity risks in a Kazakhstani population.
20570966 Nonsecretory fucosyltransferase 2 (FUT2) status is associated with Crohn's disease.