Normal allele: CC
Breakage causes a deficiency of the active form of vitamin B6, pyridoxal-5'-phosphate (p-5-p). Supplemental intake of p-5-p is recommended.
Polymorphism rs4654748 is related to topics like this:
Research and publications:
19744961 Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.
21115529 Genetics and genomics of human ageing.
31666285 Common and Rare Sequence Variants Influencing Tumor Biomarkers in Blood.
33170161 Genetic test for the prescription of diets in support of physical activity.