Normal allele: CC
A common missense variant in the LRRK2 gene associated with high risk of Parkinson's disease.
Polymorphism rs34410987 is related to topics like this:
Research and publications:
19472409 LRRK2 gene variation and its contribution to Parkinson disease.
20301387 LRRK2 Parkinson Disease.
24488318 Structural and functional in silico analysis of LRRK2 missense substitutions.
29812962 Genetic Analysis of LRRK1 and LRRK2 Variants in Essential Tremor Patients.
21885347 Association of LRRK2 exonic variants with Parkinson's disease susceptibility: a case-control study.
27653456 Systematic analysis of genetic variants in Han Chinese patients with sporadic Parkinson's disease.
17482357 Genetic analysis of the LRRK2 P755L variant in Caucasian patients with Parkinson's disease.
18265005 Pathogenicity of the LRRK2 P755L variant in Parkinson's disease.
18923807 LRRK2 P755L variant in sporadic Parkinson's disease.
21406209 LRRK2 Pro755Leu variant in ethnic Chinese with Parkinson's disease.
22575234 Quantifying the impact of LRRK2 exonic variants on Parkinson's disease risk: a meta-analysis.