Normal allele: GG
LRRK2 G2385R variant is a risk factor for sporadic Parkinson's disease in the population (3.3-fold increased risk).
Polymorphism rs33949390 is related to topics like this:
Research and publications:
18412265 Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease.
19854095 The LRRK2 G2385R variant is a risk factor for sporadic Parkinson's disease in the Korean population.
20186690 Multiple LRRK2 variants modulate risk of Parkinson disease: a Chinese multicenter study.
20301387 LRRK2 Parkinson Disease.
21885347 Association of LRRK2 exonic variants with Parkinson's disease susceptibility: a case-control study.
22373437 Identification of functional genetic variation in exome sequence analysis.
27653456 Systematic analysis of genetic variants in Han Chinese patients with sporadic Parkinson's disease.
29812962 Genetic Analysis of LRRK1 and LRRK2 Variants in Essential Tremor Patients.