SNP information rs28897727

Research and publications:

  9971877   Global sequence diversity of BRCA2: analysis of 71 breast cancer families and 95 control individuals of worldwide populations.

  11239456   Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

  12215251   Characterization of common BRCA1 and BRCA2 variants.

  12872265   BRCA1 and BRCA2 mutations in breast/ovarian cancer patients from central Italy.

  14507240   BRCA1, BRCA2 and CHEK2 (1100 del C) germline mutations in hereditary breast and ovarian cancer families in South India.

  15635067   Prevalence of BRCA2 mutations in a hospital based series of unselected breast cancer cases.

  15937124   BRCA2 BRC motifs bind RAD51-DNA filaments.

  16905680   Evaluation of BRCA1 and BRCA2 mutation prevalence, risk prediction models and a multistep testing approach in French-Canadian families with high risk of breast and ovarian cancer.

  18284688   Evaluation of unclassified variants in the breast cancer susceptibility genes BRCA1 and BRCA2 using five methods: results from a population-based study of young breast cancer patients.

  18607349   Mouse embryonic stem cell-based functional assay to evaluate mutations in BRCA2.

  19661094   Missense polymorphisms in BRCA1 and BRCA2 and risk of breast and ovarian cancer.

  21520273   Assessment of rare BRCA1 and BRCA2 variants of unknown significance using hierarchical modeling.

  21702907   A high-throughput protocol for mutation scanning of the BRCA1 and BRCA2 genes.

  21952622   BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patients.

  21990134   A review of a multifactorial probability-based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS).

  22703879   Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes.

  22792358   Association between genetic variants in DNA and histone methylation and telomere length.

  23767878   BRCA1/2 mutation screening in high-risk breast/ovarian cancer families and sporadic cancer patient surveilling for hidden high-risk families.

  23961350   BRCA1 And BRCA2 analysis of Argentinean breast/ovarian cancer patients selected for age and family history highlights a role for novel mutations of putative south-American origin.

  24728327   Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.

  25741868   Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.

  29458332   Identification of genetic variants for clinical management of familial colorectal tumors.

  32039725   Germline variants in DNA repair genes associated with hereditary breast and ovarian cancer syndrome: analysis of a 21 gene panel in the Brazilian population.