Normal allele: CC
Polymorphism in folic acid pathway genes causing B12 deficiency and increased homocysteine.
Polymorphism rs2287780 is related to topics like this:
Vitamin B9 (folic acid)Vitamin B12Methylation and homocysteine
Research and publications:
19683694 Genetic association study of putative functional single nucleotide polymorphisms of genes in folate metabolism and spina bifida
19936946 Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer
20099281 Blood leukocyte DNA hypomethylation and gastric cancer risk in a high-risk Polish population.
20445798 Chromosome 5p Region SNPs Are Associated with Risk of NSCLC among Women.
20615890 A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk.
23446900 One-carbon metabolism factors and leukocyte telomere length.
24524080 The effect of multiple single nucleotide polymorphisms in the folic acid pathway genes on homocysteine metabolism.