SNP information rs2076756

Research and publications:

  16600026   Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway

  17684544   Systematic association mapping identifies NELL1 as a novel IBD disease gene.

  18758464   Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.

  19408013   Strategies and issues in the detection of pathway enrichment in genome-wide association studies

  19434077   Detecting gene-gene interactions that underlie human diseases.

  20505004   On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20876667   Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

  21102463   Genome-wide meta-analysis increases the number of confirmed susceptibility loci for Crohn's disease to 71.

  21121902   Detecting epistatic SNPs associated with complex diseases via a Bayesian classification tree search method.

  21209938   NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common variants of the Crohn's disease susceptibility gene.

  21333900   The role of genetics in IBS

  21427131   Improved Crohn's disease risk prediction using a multilocus approach.

  21548950   Evaluation of 22 genetic variants with risk for Crohn's disease in an Ashkenazi Jewish population: a case-control study.

  21745515   Role of NOD1/CARD4 and NOD2/CARD15 gene polymorphisms in cancer etiology.

  22127647   A novel bayesian graphical model for genome-wide multi-SNP association mapping.

  22152681   Dissecting the genetics of complex inheritance: linkage disequilibrium mapping provides insight into Crohn disease.

  22242114   The role of osteopontin haplotypes (OPN/SPP1) in susceptibility to Crohn's disease.

  22319155   Crohn's disease risk alleles at the NOD2 locus are maintained by natural selection on standing variation.

  22412388   Genome-wide scanning of Crohn's disease of Ashkenazi Jews suggests new susceptibility loci.

  22457781   Variants in the PTPN2 gene are associated with susceptibility to both Crohn's disease and ulcerative colitis, supporting a common genetic basis for the disease.

  22770979   Presence of multiple independent effects in risk loci of common complex human diseases.

  23300802   Polymorphisms modulating PTGER4 expression in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites.

  23365659   IRGM variants and susceptibility to inflammatory bowel disease in the German population.

  23725363   Prediction of complex Crohn's disease and surgery: phenotypes, genetics, serology and psychological characteristics of a population-based cohort.

  24223725   Intestinal DMBT1 expression is modulated by IL23R variants associated with Crohn's disease and a DMBT1 variant that affects the binding of the transcription factors CREB1 and ATF-2.

  25664710   Genetic determinants associated with early age of diagnosis of IBD.

  26833331   Retrospective Binary-Trait Association Test Elucidates Genetic Architecture of Crohn Disease.

  27153677   Assessing statistical significance in multivariable genome wide association analysis.

  27303667   Genetic influences on the development of fibrosis in Crohn's disease.

  27336838   Blood and gut eQTLs from an anti-TNF-resistant Crohn's disease cohort inform genetic association loci for IBD.

  27812365   Shared Genetic Etiology of Autoimmune Diseases in Patients from a Biorepository Linked to De-identified Electronic Health Records.

  27892471   Combining Multiple Hypothesis Testing with Machine Learning Increases the Statistical Power of Genome-wide Association Studies.

  28633443   NOD2 Genetic Variants Predispose One of Two Familial Adenomatous Polyposis Siblings to Pouchitis Through Microbiome Dysbiosis.

  29434451   Impaired bioactivity of granulocyte-macrophage colony-stimulating factor accelerates surgical relapse in Crohn's disease of the ileum.

  31714311   Clinical and genetic factors influence the time to surgical recurrence after ileocolectomy for Crohn's disease.

  32045400   Clinical and genetic factors associated with complications after Crohn's ileocolectomy.