SNP information rs17696736

Research and publications:

  17554260   Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

  18077426   Runs of homozygosity reveal highly penetrant recessive loci in schizophrenia.

  18224312   Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment

  18423522   Estimating odds ratios in genome scans: an approximate conditional likelihood approach

  18533027   Worldwide population differentiation at disease-associated SNPs

  18556337   Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1)

  18840781   Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes.

  18853133   Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

  19140132   Unbiased estimation of odds ratios: combining genomewide association scans with replication studies.

  19359276   Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes.

  19430479   Genome-wide association study of blood pressure and hypertension.

  19565500   Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis

  19639606   Correcting the “winner's curse” in odds ratios based on genome-wide association results for major complex human diseases.

  19820697   A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.

  19838195   A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

  19956105   Reassessment of the type I diabetes association of the OAS1 locus.

  19956108   Analysis of 55 autoimmune disease and type II diabetes loci: further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type I diabetes loci, and support for a new locus, 12q13.3-q14.1.

  20088021   Screen and clean: a tool for identifying interactions in genome-wide association studies.

  20089178   Allelic variants in the PHTF1-PTPN22, C12orf30 and CD226 regions as candidate susceptibility factors for the type 1 diabetes in the Estonian population.

  20369022   Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.

  20549515   Genome-wide searching of rare genetic variants in WTCCC data.

  20647273   Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.

  20722033   The susceptibility loci juvenile idiopathic arthritis shares with other autoimmune diseases extend to PTPN2, COG6, and ANGPT1.

  20885991   Advances and challenges in biomarker development for type 1 diabetes prediction and prevention using omic technologies.

  21036813   A variable selection method for genome-wide association studies.

  21060006   Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array.

  21507254   Geographic differences in allele frequencies of susceptibility SNPs for cardiovascular disease.

  21765104   Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction.

  22046141   Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus.

  22140419   BLOCK-BASED BAYESIAN EPISTASIS ASSOCIATION MAPPING WITH APPLICATION TO WTCCC TYPE 1 DIABETES DATA.

  22190364   Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

  22293688   1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.

  22496761   Improving power of genome-wide association studies with weighted false discovery rate control and prioritized subset analysis.

  23297363   Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot.

  24178511   Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

  24936253   12q24 locus association with type 1 diabetes: SH2B3 or ATXN2?

  27153677   Assessing statistical significance in multivariable genome wide association analysis.

  27716086   Association of CD247 (CD3ζ) gene polymorphisms with T1D and AITD in the population of northern Sweden.

  27892471   Combining Multiple Hypothesis Testing with Machine Learning Increases the Statistical Power of Genome-wide Association Studies.

  29954342   LPG: A four-group probabilistic approach to leveraging pleiotropy in genome-wide association studies.

  30888520   Genetic Mechanisms Highlight Shared Pathways for the Pathogenesis of Polygenic Type 1 Diabetes and Monogenic Autoimmune Diabetes.