Normal allele: GG
A study involving 45,078subjects confirms an association between SNCA alpha-synuclein alpha rs11931074 and Parkinson's disease.
Polymorphism rs11931074 is related to topics like this:
Research and publications:
19063963 Genetic predisposition to Parkinson's disease.
19475667 SNCA variants are associated with increased risk for multiple system atrophy.
19771175 Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.
19915575 Genome-wide association study identifies genetic risk underlying Parkinson's disease.
20413655 Genetics of neurodegenerative diseases: insights from high-throughput resequencing.
20961626 β-Synuclein and dopamine at the crossroads of Parkinson's disease.
21058943 Replication of GWAS associations for GAK and MAPT in Parkinson's disease.
21248740 Genome-wide association study confirms extant PD risk loci among the Dutch.
21391235 Independent and joint effects of the MAPT and SNCA genes in Parkinson disease.
21412835 Common variants in the PARK and related genes loci and Parkinson's disease.
22086882 No association between Parkinson disease alleles and the risk of melanoma.
24868370 Human genetic variation and Parkinson's disease.
25373618 Analysis of COQ2 gene in multiple system atrophy.
25623333 Polygenic determinants of Parkinson's disease in a Chinese population.
25656566 Alpha-synuclein polymorphisms (SNCA) and susceptibility to Parkinson's disease: a meta-analysis.
27628759 Transcriptional Dynamics at Brain Enhancers: from Functional Specialization to Neurodegeneration.
27629089 A genome-wide association study in multiple system atrophy.
27686748 Improving the accuracy of predicting progression of Parkinson's disease.
28357149 Festination correlates with SNCA polymorphisms in Chinese patients with Parkinson's disease.
28979204 Hyposmia Is Associated with RBD for PD Patients with Variants of SNCA.
30316070 SNCA variants and alpha-synuclein levels in CD45 blood cells in Parkinson's disease.
30631417 Genetic influence on clinical features of Parkinson's disease: the SNCA-rs11931074 study.
32432761 Association study of SNCA gene polymorphisms with schizophrenia in a Chinese North Han population.
34946922 Microarray genotyping identifies novel loci associated with Parkinson's disease dementia.