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SNP information rs11931074

RS11931074

Normal allele: GG

A study involving 45,078subjects confirms an association between SNCA alpha-synuclein alpha rs11931074 and Parkinson's disease.

Polymorphism rs11931074 is related to topics like this:

Parkinson is a genetic disease

A disorder that progresses gradually within the nervous system is known as Parkinson's disease. It...


Research and publications:

  17531291   Familial genes in sporadic diseases: common alpha-synuclein gene variants associated with Parkinson's disease.

  19063963   Genetic predisposition to Parkinson's disease.

  19475667   SNCA variants are associated with increased risk for multiple system atrophy.

  19771175   Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.

  19915575   Genome-wide association study identifies genetic risk underlying Parkinson's disease.

  20070850   Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.

  20413655   Genetics of neurodegenerative diseases: insights from high-throughput resequencing.

  20961626   β-Synuclein and dopamine at the crossroads of Parkinson's disease.

  21058943   Replication of GWAS associations for GAK and MAPT in Parkinson's disease.

  21248740   Genome-wide association study confirms extant PD risk loci among the Dutch.

  21391235   Independent and joint effects of the MAPT and SNCA genes in Parkinson disease.

  21412835   Common variants in the PARK and related genes loci and Parkinson's disease.

  21812969   Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.

  22086882   No association between Parkinson disease alleles and the risk of melanoma.

  23820587   The Genome-Wide Alzheimer's and Parkinson's Disease Association studies the most common diseases and risk of Parkinson's disease in the Korean population.

  23853107   Analysis of loci associated with genome-wide association study in Parkinson's disease in mainland China.

  23962496   The protective effect of LRRK2 p.R1398H on Parkinson's disease risk is independent of MAPT and SNCA variants.

  24418406   Alpha-synuclein transcript isoforms in three different brain regions in Parkinson's disease and healthy controls in relation to the SNCA rs356165/rs11931074 polymorphism.

  24868370   Human genetic variation and Parkinson's disease.

  25373618   Analysis of COQ2 gene in multiple system atrophy.

  25427997   SNP rs11931074 of the SNCA gene may not be associated with multiple system atrophy in Chinese population.

  25623333   Polygenic determinants of Parkinson's disease in a Chinese population.

  25656566   Alpha-synuclein polymorphisms (SNCA) and susceptibility to Parkinson's disease: a meta-analysis.

  25921825   Hyposmia correlates with SNCA variant and non-motor symptoms in Chinese patients with Parkinson's disease.

  26208350   SNCA genetic variants are associated with susceptibility to Parkinson's disease but not to amyotrophic lateral sclerosis or multiple system atrophy in a Chinese population.

  26732583   Analysis of the association between SNCA, HUSEYO and CSMD1 gene variants and Parkinson's disease in an Iranian population.

  26776090   SNCA gene variants are associated with motor progression, while MAPT gene variants are associated with Parkinson's disease severity.

  27335051   Total salivary α-synuclein, oligomeric α-synuclein, and SNCA variants in patients with Parkinson's disease.

  27628759   Transcriptional Dynamics at Brain Enhancers: from Functional Specialization to Neurodegeneration.

  27629089   A genome-wide association study in multiple system atrophy.

  27686748   Improving the accuracy of predicting progression of Parkinson's disease.

  28357149   Festination correlates with SNCA polymorphisms in Chinese patients with Parkinson's disease.

  28676755   SNCA gene variants are associated with Parkinson's disease risk and cognitive symptoms in a Brazilian sample.

  28927418   A systematic review and integrative approach to decipher the overall molecular link between levodopa response and Parkinson's disease.

  28979204   Hyposmia Is Associated with RBD for PD Patients with Variants of SNCA.

  30120622   An updated analysis involving 45,078 subjects confirms the association between SNCA rs11931074 and Parkinson's disease.

  30316070   SNCA variants and alpha-synuclein levels in CD45 blood cells in Parkinson's disease.

  30410434   Comprehensive analysis of the relationship between SNCA polymorphisms and the risk of Parkinson's disease.

  30424941   Association of SNCA variants with α-synuclein of the gastric and colon mucosa in Parkinson's disease.

  30631417   Genetic influence on clinical features of Parkinson's disease: the SNCA-rs11931074 study.

  31102707   Alpha-synuclein gene polymorphism influences the risk of dementia in Han Chinese with Parkinson's disease.

  31243602   SNCA rs11931074 polymorphism correlates with spontaneous brain activity and motor symptoms in Chinese patients with Parkinson's disease.

  31758346   Association between alpha-synuclein (SNCA) rs11931074 variation and Parkinson's disease susceptibility: an updated meta-analysis of 41,811 patients.

  32432761   Association study of SNCA gene polymorphisms with schizophrenia in a Chinese North Han population.

  34946922   Microarray genotyping identifies novel loci associated with Parkinson's disease dementia.

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