SNP information rs10401969

Research and publications:

  19060906   Common variants at 30 loci contribute to polygenic dyslipidemia.

  19656773   A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.

  19951432   Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease

  20839009   Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica.

  20864672   Genetic variants influencing circulating lipid levels and risk of coronary artery disease.

  21041806   Genetic determinants of plasma triglycerides.

  21527746   Triglycerides and heart disease: still a hypothesis?

  21558551   Genetic loci for blood lipid levels identified by linkage and association analyses in Caribbean Hispanics.

  21597005   An increased burden of common and rare lipid-associated risk alleles contributes to the phenotypic spectrum of hypertriglyceridemia.

  21860704   Implications of discoveries from genome-wide association studies in current cardiovascular practice.

  21862702   Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk.

  22022282   A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains.

  22994408   Transferability and fine mapping of genome-wide associated loci for lipids in African Americans.

  23092954   SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits

  23119086   Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate.

  23393188   Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells.

  23696881   Imputation of variants from the 1000 Genomes Project modestly improves known associations and can identify low-frequency variant-phenotype associations undetected by HapMap based imputation.

  24843659   Insights into the genetic basis of type 2 diabetes.

  24845081   Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study

  24864266   Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.

  24879641   Inheritance of rare functional GCKR variants and their contribution to triglyceride levels in families.

  24927523   TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content.

  25239271   Fine mapping of type 2 diabetes susceptibility loci.

  25246029   Genome-wide analysis of hepatic lipid content in extreme obesity.

  25774817   Genetics of type 2 diabetes-pitfalls and possibilities.

  26676813   Insights from Genome-Wide Association Analyses of Nonalcoholic Fatty Liver Disease.

  26780889   Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

  26905813   Gender-specific associations of genetic variants with metabolic syndrome components in the Tunisian population.

  27286809   Bivariate genome-wide association study identifies novel pleiotropic loci for lipids and inflammation.

  27312935   Genetics of Insulin Resistance and the Metabolic Syndrome.

  27547017   Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review.

  28577571   Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

  28821857   CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes.

  30132178   Single-nucleotide rs738409 polymorphisms in the PNPLA3 gene are strongly associated with alcoholic liver disease in Han Chinese males.

  30589442   Biomarker and Genomic Risk Factors for Liver Function Test Abnormality in Hazardous Drinkers.

  30782980   Lipid-related genetic polymorphisms significantly modulate the association between lipids and disability progression in multiple sclerosis.

  32568739   Association of the NCAN-TM6SF2-CILP2-PBX4-SUGP1-MAU2 SNPs and gene-gene and gene-environment interactions with serum lipid levels.

  33105679   Genetic Variants Associated with Non-Alcoholic Fatty Liver Disease Do Not Associate with Measures of Sub-Clinical Atherosclerosis: Results from the IMPROVE Study.

  34656649   A genetic risk score and diabetes predict development of alcohol-related cirrhosis in drinkers.