SNP information rs78378222

Research and publications:

  21946351   A germline variant in the TP53 polyadenylation signal confers cancer susceptibility.

  22706378   Rare TP53 genetic variant associated with glioma risk and outcome.

  22800615   A functional germline variant in the P53 polyadenylation signal and risk of esophageal squamous cell carcinoma.

  23571737   Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222.

  23742673   Association between a rare novel TP53 variant (rs78378222) and melanoma, squamous cell carcinoma of head and neck and lung cancer susceptibility in non-Hispanic Whites.

  24634504   Rare variants in TP53 and susceptibility to neuroblastoma.

  24764655   Genetic variations in colorectal cancer risk and clinical outcome.

  25422255   Absence of the TP53 poly-A signal sequence variant rs78378222 in oral, cervical and breast cancers in South India.

  25907361   Further Confirmation of Germline Glioma Risk Variant rs78378222 in TP53 and Its Implication in Tumor Tissues via Integrative Analysis of TCGA Data.

  26839018   Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma.

  26906551   Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study.

  26992833   The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations.

  27067391   A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer.

  27147571   A novel TP53 variant (rs78378222 A > C) in the polyadenylation signal is associated with increased cancer susceptibility: evidence from a meta-analysis.

  27324920   Complex Selection on Human Polyadenylation Signals Revealed by Polymorphism and Divergence Data.

  27780202   Relation between Established Glioma Risk Variants and DNA Methylation in the Tumor.

  30086788   Breast cancer patients suggestive of Li-Fraumeni syndrome: mutational spectrum, candidate genes, and unexplained heredity.

  30194396   Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits.

  31637880   MicroRNA-binding site polymorphisms and risk of colorectal cancer: A systematic review and meta-analysis.

  31699989   Tissue-specific microRNA expression alters cancer susceptibility conferred by a TP53 noncoding variant.

  32591342   Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits.

  33558336   Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response.

  34104963   Assessing the impact of alcohol consumption on the genetic contribution to mean corpuscular volume.