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SNP information rs7794745

Normal allele: AA

Associated with an increased risk of autism based on a study of 148 sick children from families with two other children with autism. Causes changes in fronto-occipital circuitry and cerebellar structure associated with autism.

Polymorphism rs7794745 is related to topics like this:


Research and publications:

  18179894   A common genetic variant in the neurexin superfamily member CNTNAP2 increases familial risk of autism.

  19456320   A genome-wide association study of autism reveals a common novel risk locus at 5p14.1.

  20176116   Normal variation in fronto-occipital circuitry and cerebellar structure with an autism-associated polymorphism of CNTNAP2.

  20414140   Association analysis of CNTNAP2 polymorphisms with autism in the Chinese Han population.

  20446882   Do candidate genes discriminate patients with an autism spectrum disorder from those with attention deficit/hyperactivity disorder and is there an effect of lifetime substance use disorders?

  20838614   Traits contributing to the autistic spectrum.

  21165691   Investigation of dyslexia and SLI risk variants in reading- and language-impaired subjects.

  21193173   A common genetic variant in the neurexin superfamily member CNTNAP2 is associated with increased risk for selective mutism and social anxiety-related traits

  21310003   CNTNAP2 variants affect early language development in the general population.

  21987501   Genetic variation in CNTNAP2 alters brain function during linguistic processing in healthy individuals.

  22017886   Autism risk assessment in siblings of affected children using sex-specific genetic scores.

  22105624   The genetics of attention deficit/hyperactivity disorder in adults, a review.

  22365836   What does CNTNAP2 reveal about autism spectrum disorder?

  22843504   Individual common variants exert weak effects on the risk for autism spectrum disorders.

  23277129   Analysis of two language-related genes in autism: a case-control association study of FOXP2 and CNTNAP2.

  23715297   Haplotype structure enables prioritization of common markers and candidate genes in autism spectrum disorder.

  24147096   Defining the contribution of CNTNAP2 to autism susceptibility.

  26322220   A comprehensive meta-analysis of common genetic variants in autism spectrum conditions.

  26559825   CNTNAP2 gene in high functioning autism: no association according to family and meta-analysis approaches.

  28284582   The association of CNTNAP2 rs7794745 gene polymorphism and autism in Iranian population.

  28498932   From CNTNAP2 to Early Expressive Language in Infancy: The Mediation Role of Rapid Auditory Processing.

  28738218   Common variation in the autism risk gene CNTNAP2, brain structural connectivity and multisensory speech integration.

  30586385   Comprehensive cross-disorder analyses of CNTNAP2 suggest it is unlikely to be a primary risk gene for psychiatric disorders.

  30681286   Association between CNTNAP2 polymorphisms and autism: A family-based study in the chinese han population and a meta-analysis combined with GWAS data of psychiatric genomics consortium.

  33901431   Common variants of the autism-associated CNTNAP2 gene contribute to the modulatory effect of social function mediated by temporal cortex.

  33950402   CNTNAP2 gene polymorphisms in autism spectrum disorder and language impairment among Bangladeshi children: a case-control study combined with a meta-analysis.

  34257739   Association between Genetic Variants in DUSP15, CNTNAP2, and PCDHA Genes and Risk of Childhood Autism Spectrum Disorder.