SNP information rs744373

Research and publications:

  20460622   Genome-wide analysis of genetic loci associated with Alzheimer disease

  21220176   Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations.

  22159054   A comprehensive genetic association study of Alzheimer disease in African Americans.

  22482072   Genomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.

  22833209   Genome-wide association study identifies multiple novel loci associated with disease progression in subjects with mild cognitive impairment.

  23399914   Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

  24670887   Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD.

  25108264   Genomics in neurological disorders.

  25630570   Bridging Integrator 1 (BIN1) Genotype Effects on Working Memory, Hippocampal Volume, and Functional Connectivity in Young Healthy Individuals.

  26154020   A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia.

  26631617   Gene expression variance in hippocampal tissue of temporal lobe epilepsy patients corresponds to differential memory performance.

  29764032   [Genes polymorphism of BIN1 and ApoE in patients with amnestic mild cognitive impairment from Enshi Tujia area].

  30503753   Analysis of cognitive performance and polymorphisms of SORL1, PVRL2, CR1, TOMM40, APOE, PICALM, GWAS_14q, CLU, and BIN1 in patients with mild cognitive impairment and cognitively healthy controls.

  30992433   The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory.

  34752346   Analysis of cognitive performance and polymorphisms of SORL1, PVRL2, CR1, TOMM40, APOE, PICALM, GWAS_14q, CLU, and BIN1 in patients with mild cognitive impairment and cognitively healthy controls.

  35229019   Lack of association between bridging integrator 1 (BIN1) rs744373 polymorphism and tau-PET load in cognitively intact older adults.

  19734902   Genome-wide association study identifies CLU and PICALM variants associated with Alzheimer's disease.

  21132329   Study of 15 candidate genes responsible for late-onset Alzheimer's disease.

  21312009   Strengths and limitations of a genome-wide association study approach for identifying Alzheimer's disease genes.

  21321396   Replication of the association of BIN1 with Alzheimer's disease and assessment of genetic interactions.

  21347408   Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers of Alzheimer's disease.

  21379329   Genome-wide association of late-onset familial Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.

  21390209   Meta-analysis of a genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.

  21459483   Using cerebrospinal fluid biomarkers to replicate genetic associations in Alzheimer's disease.

  21460840   Common variants ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

  21547229   Neuroimaging indicators as endophenotypes in Alzheimer's disease.

  21627779   The membrane 4-domain subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.

  21766012   Alzheimer's disease genes are associated with rates of cognitive aging in the Lothian cohorts born in 1921 and 1936.

  22005930   Genome-wide study of the association of Alzheimer's disease with psychotic symptoms.

  22430674   A genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease.

  23180304   Genetic risk assessment predicting accelerated progression from mild cognitive impairment to Alzheimer's disease.

  23570733   The rs744373 polymorphism of the BIN1 gene contributes to the development of Alzheimer's disease in East Asian populations.

  23573206   Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.

  23857120   The ATP5H/KCTD2 locus is associated with risk of Alzheimer's disease.

  25022885   Genetic evidence for the involvement of variants in the APOE, BIN1, CR1 and PICALM loci in the risk of late-onset Alzheimer's disease and assessment of interactions with APOE genotypes.

  25452228   Validation of GWAS-identified risk loci for Alzheimer's disease in a Han Chinese population.

  25461955   Common Bin1 variants are associated with sporadic Alzheimer's disease in the Han population.

  26680604   Polygenic analysis of late-onset Alzheimer's disease in mainland China.

  26733302   Study of the association of the BIN1 and IL-6 genes in Alzheimer's disease.

  26768592   Association between interleukin-1A, interleukin-1B and bridge integrator 1 polymorphisms and Alzheimer's disease: a conventional and cumulative meta-analysis.

  26846281   Bridge integrator 1 gene rs744373 polymorphism and risk of Alzheimer's disease in Caucasian and Asian populations: an updated meta-analysis.

  26993346   Genetic risk factors for posterior cortical atrophy variant of Alzheimer's disease.

  27274215   Genes associated with Alzheimer's disease: review and current status.

  27610127   Analysis of heterogeneous multimodal biomarkers of Alzheimer's disease using a Bayesian network.

  27799753   Mutations associated with early onset Alzheimer's disease have been found in Asian countries.

  28084078   Association of major GWAS genes with late-onset Alzheimer's disease in a Colombian population.

  28316001   Associations of Alzheimer's disease candidate gene polymorphisms BIN1, CLU, CR1 and PICALM with gestational diabetes and impaired glucose tolerance.

  29504051   Updated meta-analysis of BIN1, CR1, MS4A6A, CLU, and ABCA7 variants in Alzheimer's disease.

  30214536   Association of OGG1 and DLST promoter methylation with Alzheimer's disease in a population of Xinjiang.

  30378268   Association of genetic loci of Alzheimer's disease with mild behavioral disorders.

  31469155   Combined risk effect of BIN1, CLU and APOE genes in Alzheimer's disease.

  31874619   The BIN1 rs744373 variant shows different associations with Alzheimer's disease in Caucasian and Asian populations.

  33815092   Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.

  34060233   Alzheimer's disease risk SNP BIN1 rs744373 is associated with faster Aβ-associated tau accumulation and cognitive decline.

  34072165   Genetic predisposition to Alzheimer's disease is associated with enlarged perivascular spaces in the centrum semiovale.

  34975449   Structural covariance network as an endophenotype in Alzheimer's disease susceptibility single nucleotide polymorphisms and correlations with cognitive outcomes.

  34978146   BIN1 rs744373, located in brain tissue enhancers, enhances BIN1 mRNA expression, thereby leading to Alzheimer's disease.

  35028746   The influence of Alzheimer's disease susceptibility loci on the surface morphology of the lateral ventricle in elderly people.

  35537244   Generation of iPSC line KEIOi005-A from urine-derived cells (UDC) of a donor with mild Alzheimer's disease (AD) with multiple-risk SNPs for sporadic Alzheimer's disease (SAD).

  35546756   Association of polymorphisms of the BIN1, CLU and IDE genes with susceptibility to Alzheimer's disease: meta-analysis data.