SNP information rs4977756

Research and publications:

  19578366   Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.

  19578367   Genome-wide association study identifies five susceptibility loci for glioma.

  20211558   Genetic advances in glioma: susceptibility genes and networks.

  20212223   New insights into susceptibility to glioma.

  20368557   Polymorphisms of LIG4, BTBD2, HMGA2, and RTEL1 genes involved in the double-strand break repair pathway predict glioblastoma survival.

  20462933   Interaction between 5 genetic variants and allergy in glioma risk.

  20505153   A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

  20585100   Genome-wide association studies of cancer.

  20847058   Genetic risk profiles identify different molecular etiologies for glioma.

  21203894   Cancer susceptibility variants and the risk of adult glioma in a US case-control study.

  21270820   A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry.

  21531791   Chromosome 7p11.2 (EGFR) variation influences glioma risk.

  21532571   Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1.

  21742680   Associations of high-grade glioma with glioma risk alleles and histories of allergy and smoking.

  21825990   Genetic causes of glioma: new leads in the labyrinth.

  21827660   Combinations of newly confirmed Glioma-Associated loci link regions on chromosomes 1 and 9 to increased disease risk.

  21920947   Joint associations between genetic variants and reproductive factors in glioma risk among women.

  22037877   Genome-wide high-density SNP linkage search for glioma susceptibility loci: results from the Gliogene Consortium.

  22173078   Current concepts on primary open-angle glaucoma genetics: a contribution to disease pathophysiology and future treatment.

  22570617   Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.

  22761751   CDKN2B polymorphism is associated with primary open-angle glaucoma (POAG) in the Afro-Caribbean population of Barbados, West Indies.

  22792221   Common variants on chromosome 9p21 are associated with normal tension glaucoma.

  23091480   Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: a novel candidate SNP approach.

  23115063   Known glioma risk loci are associated with glioma with a family history of brain tumours -- a case-control gene association study.

  23161787   Association between glioma susceptibility loci and tumour pathology defines specific molecular etiologies.

  23236348   EGFR gene variants are associated with specific somatic aberrations in glioma.

  23903690   Joint effects between five identified risk variants, allergy, and autoimmune conditions on glioma risk.

  23963167   Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry.

  24002674   Genome-wide association study and meta-analysis of intraocular pressure.

  24274136   Biobanking across the phenome - at the center of chronic disease research.

  24676469   Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets.

  24681604   Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia.

  24875940   Evaluation of genetic association of the INK4 locus with primary open angle glaucoma in East Indian population.

  25242315   Association of open-angle glaucoma loci with incident glaucoma in the Blue Mountains Eye Study.

  25489222   Association of known common genetic variants with primary open angle, primary angle closure, and pseudoexfoliation glaucoma in Pakistani cohorts.

  25525164   Exome array analysis identifies CAV1/CAV2 as a susceptibility locus for intraocular pressure.

  25849520   Quantitative Trait Locus Analysis of SIX1-SIX6 With Retinal Nerve Fiber Layer Thickness in Individuals of European Descent.

  26014354   CCDC26, CDKN2BAS, RTEL1 and TERT Polymorphisms in pediatric brain tumor susceptibility.

  26243184   An Updated and Comprehensive Meta-Analysis of Association Between Seven Hot Loci Polymorphisms from Eight GWAS and Glioma Risk.

  26545403   A GWAS Meta-analysis and Replication Study Identifies a Novel Locus within CLPTM1L/TERT Associated with Nasopharyngeal Carcinoma in Individuals of Chinese Ancestry.

  26577493   Effect of CDKN2A/B rs4977756 polymorphism on glioma risk: a meta-analysis of 16 studies including 24077 participants.

  26677855   Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity.

  26690118   An Updated Review on the Genetics of Primary Open Angle Glaucoma.

  26732429   Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.

  26835415   The rs11515 Polymorphism Is More Frequent and Associated With Aggressive Breast Tumors with Increased ANRIL and Decreased p16 (INK4a) Expression.

  26839018   Genetic risk variants in the CDKN2A/B, RTEL1 and EGFR genes are associated with somatic biomarkers in glioma.

  26906551   Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study.

  26958643   Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.

  27015805   Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.

  27707548   Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study.

  27780202   Relation between Established Glioma Risk Variants and DNA Methylation in the Tumor.

  28472212   Association of Glaucoma-Susceptible Genes to Regional Circumpapillary Retinal Nerve Fiber Layer Thickness and Visual Field Defects.

  28499933   Major review: Molecular genetics of primary open-angle glaucoma.

  28721823   Genetic Risk Factors for Glaucoma and Exfoliation Syndrome Identified by Genome-wide Association Studies.

  29314442   LncRNA CDKN2BAS rs2157719 genetic variant contributes to medulloblastoma predisposition.

  29891935   A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci.

  29894795   The role of CDKN2B in cardiovascular risk in ethnic Saudi Arabs: A validation study.

  30317457   Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations.

  30405695   Lack of Association of rs1192415 in TGFBR3-CDC7 With Visual Field Progression: A Cohort Study in Chinese Open Angle Glaucoma Patients.

  30607769   Pharmacogenetic Correlates of Antipsychotic-Induced Weight Gain in the Chinese Population.

  31436842   Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis.

  31632126   Genetic Analysis Of ABCA1 Gene Of Primary Glaucoma In Jordanian Arab Population.

  31721021   Replication of GWAS identifies RTEL1, CDKN2A/B, and PHLDB1 SNPs as risk factors in Portuguese gliomas patients.

  32509935   Dataset of allele, genotype and haplotype frequencies of five polymorphisms CDKN2B-AS1 gene in Russian patients with primary open-angle glaucoma.

  32511397   SARS-CoV2 (COVID-19) Structural/Evolution Dynamicome: Insights into functional evolution and human genomics.

  32825664   Molecular Genetics and Functional Analysis Implicate CDKN2BAS1-CDKN2B Involvement in POAG Pathogenesis.

  33396423   Molecular Genetics of Glaucoma: Subtype and Ethnicity Considerations.

  33397358   Genetic association between CDKN2B/CDKN2B-AS1 gene polymorphisms with primary glaucoma in a North Indian cohort: an original study and an updated meta-analysis.

  33605984   The Role of Genetic Ancestry as a Risk Factor for Primary Open-angle Glaucoma in African Americans.

  34387529   The haplotype of the CDKN2B-AS1 gene is associated with primary open-angle glaucoma and pseudoexfoliation glaucoma in the Caucasian population of Central Russia.

  25027321   Genome-wide association and admixture analysis of glaucoma from the Women's Health Initiative.