SNP information rs4977574

Research and publications:

  18987759   Genetic testing for atherosclerosis risk: inevitability or pipe dream?

  19198609   Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

  19214202   Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis.

  19463184   Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease.

  19956433   Genetics of coronary artery disease: focus on genome-wide association studies.

  20031606   The 9p21 myocardial infarction risk allele increases risk of peripheral artery disease in older people.

  20729558   Improved prediction of cardiovascular disease based on a panel of single nucleotide polymorphisms identified through genome-wide association studies.

  20835900   Genetics of diabetes complications.

  20858905   Association of single nucleotide polymorphisms on chromosome 9p21.3 with platelet reactivity: a potential mechanism for increased vascular disease.

  20971364   A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.

  21239051   Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.

  21242481   Genetic risk score and risk of myocardial infarction in Hispanics.

  21347282   Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

  21369780   Genome-wide association studies in atherosclerosis.

  21375403   The relationship between polymorphisms on chromosome 9p21 and age of onset of coronary heart disease in black and white women.

  21378990   Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

  21705410   The association between variants on chromosome 9p21 and inflammatory biomarkers in ethnically diverse women with coronary heart disease: a pilot study.

  21775993   Comparing strategies to fine-map the association of common SNPs at chromosome 9p21 with type 2 diabetes and myocardial infarction.

  21860704   Implications of discoveries from genome-wide association studies in current cardiovascular practice.

  21875899   Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour.

  21971053   Genome-wide association study of coronary artery disease in the Japanese.

  22022235   The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study.

  22144573   Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.

  22152955   Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies.

  22199011   Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies.

  22216278   Large scale association analysis identifies three susceptibility loci for coronary artery disease.

  22295058   Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Surv

  22363065   Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke?

  22403240   Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study.

  22588700   Genetics of coronary artery disease in the 21st century.

  22745674   Genome-wide association study in a Lebanese cohort confirms PHACTR1 as a major determinant of coronary artery stenosis.

  22882272   Genetic variants associated with myocardial infarction in the PSMA6 gene and Chr9p21 are also associated with ischaemic stroke.

  22972380   Investigation of genetic risk factors for chronic adult diseases for association with preterm birth

  23468967   Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies.

  23480785   Chromosome 9p21 genetic variation explains 13% of cardiovascular disease incidence but does not improve risk prediction.

  23561647   Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction.

  23631657   Are 25 SNPs from the CARDIoGRAM study associated with ischaemic stroke?

  23828831   The impact of susceptibility loci for coronary artery disease on other vascular domains and recurrence risk.

  23870195   Genetics of coronary artery calcification among African Americans, a meta-analysis.

  23963167   Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry.

  24270849   Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data.

  24452806   Genetic analysis of the 9p21.3 CAD risk locus in Asian Indians.

  24475106   Genetic variants associated with myocardial infarction and the risk factors in Chinese population.

  24607648   Genetic variants at chromosome 9p21 and risk of first versus subsequent coronary heart disease events: a systematic review and meta-analysis.

  24834361   Update on abdominal aortic aneurysm research: from clinical to genetic studies.

  24875940   Evaluation of genetic association of the INK4 locus with primary open angle glaucoma in East Indian population.

  24906238   The association of 9p21-3 locus with coronary atherosclerosis: a systematic review and meta-analysis.

  24932356   Genetics of coronary artery disease: an update.

  25105296   Polymorphism of 9p21.3 locus is associated with 5-year survival in high-risk patients with myocardial infarction.

  25268619   Association of CDKN2BAS polymorphism rs4977574 with coronary heart disease: a case-control study and a meta-analysis.

  25542012   Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.

  25738804   Association of six genetic variants with myocardial infarction.

  25958930   Variants on Chromosome 9p21 Confer Risks of Noncardioembolic Cerebral Infarction and Carotid Plaque in the Chinese Han Population.

  26252781   Potential Signals of Natural Selection in the Top Risk Loci for Coronary Artery Disease: 9p21 and 10q11.

  26426617   Value of Chromosome 9p21 Polymorphism for Prediction of Cardiovascular Mortality in Han Chinese Without Coronary Lesions: An Observational Study.

  26789557   Common genetic variants and subclinical atherosclerosis: The Multi-Ethnic Study of Atherosclerosis (MESA).

  26885234   Association study of BUD13-ZNF259 gene rs964184 polymorphism and hemorrhagic stroke risk.

  26892960   From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.

  26958643   Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.

  26999117   Intronic Polymorphisms in the CDKN2B-AS1 Gene Are Strongly Associated with the Risk of Myocardial Infarction and Coronary Artery Disease in the Saudi Population.

  27015805   Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants.

  27042264   Genetics of cardiovascular and renal complications in diabetes.

  27096864   Chromosome 9p21 and ABCA1 Genetic Variants and Their Interactions on Coronary Heart Disease and Ischemic Stroke in a Chinese Han Population.

  27175642   Association of Genetic Polymorphisms on VEGFA and VEGFR2 With Risk of Coronary Heart Disease.

  27189168   The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease.

  27240780   The Correlation Between 9p21 Chromosome rs4977574 Polymorphism Genotypes and the Development of Coronary Artery Heart Disease.

  27386823   Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci.

  27424552   Genomics era and complex disorders: Implications of GWAS with special reference to coronary artery disease, type 2 diabetes mellitus, and cancers.

  27846637   Analysis on the Polymorphism of Chromosome Region 9p21 and the Susceptibility of Carotid Plaque.

  28057453   Association of ANRIL gene polymorphisms with major adverse cardiovascular events in hemodialysis patients.

  28138111   Association of CDKN2B-AS1 rs1333049 with Brain Diseases: A Case-control Study and a Meta-analysis.

  28243616   Data on genotypic distribution and linkage disequilibrium of several ANRIL polymorphisms in hemodialysis patients.

  28426714   A genetic risk score for CAD, psychological stress, and their interaction as predictors of CAD, fatal MI, non-fatal MI and cardiovascular death.

  28580310   ANRIL Genetic Variants in Iranian Breast Cancer Patients.

  28621612   Association of ANRIL gene polymorphisms with prostate cancer and benign prostatic hyperplasia in an Iranian population.

  28856136   Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study.

  29713948   Association Study of ANRIL Genetic Variants and Multiple Sclerosis.

  29791233   Association of a Chromosome Locus 9p21.3 CDKN2B-AS1 Variant rs4977574 with Hypertension: The TAMRISK Study.

  29802154   Association between long non-coding RNA polymorphisms and cancer risk: a meta-analysis.

  29894795   The role of CDKN2B in cardiovascular risk in ethnic Saudi Arabs: A validation study.

  29972410   Genetic Risk Analysis of Coronary Artery Disease in a Population-based Study in Portugal, Using a Genetic Risk Score of 31 Variants.

  30138332   Genetic variation in 9p21 is associated with fasting insulin in women but not men.

  30558699   Association of CDKN2B-AS1 Polymorphisms with Premature Triple-vessel Coronary Disease and Their Sex Specificity in the Chinese Population.

  30571812   Additional value of a combined genetic risk score to standard cardiovascular stratification.

  30587704   The association between the chromosome 9p21 CDKN2B-AS1 gene variants and the lipid metabolism: A pre-diagnostic biomarker for coronary artery disease.

  31543200   Genetic variants of chromosome 9p21.3 region associated with coronary artery disease and premature coronary artery disease in an Asian Indian population.

  31812071   Genetic variants within ANRIL (antisense non coding RNA in the INK4 locus) are associated with risk of psoriasis.

  31824394   The Association of SNPs Located in the CDKN2B-AS1 and LPA Genes With Carotid Artery Stenosis and Atherogenic Stroke.

  31845553   Precision Medicine and Cardiovascular Health: Insights from Mendelian Randomization Analyses.

  32066403   Analysis on the polymorphisms of site RS4977574, and RS1333045 in region 9p21 and the susceptibility of coronary heart disease in Chinese population.

  32152937   Application of Artificial Neural Network for Prediction of Risk of Multiple Sclerosis Based on Single Nucleotide Polymorphism Genotypes.

  32248921   9p21.3 coronary artery disease risk locus and interferon alpha 21: Association study in an Asian Indian population.

  32293292   Susceptible gene polymorphism in patients with three-vessel coronary artery disease.

  32390081   The Single Nucleotide Polymorphisms of Chromosome 9p21 and CD147 Were Relevant with the Carotid Plaque Risk in Acute Cerebral Infarction Patients Among Chinese Han Population.

  32623644   Association Analysis of ANRIL Polymorphisms and Haplotypes with Autism Spectrum Disorders.

  32840931   Association of GWAS-susceptibility loci with ischemic stroke recurrence in a Han Chinese population.

  33054494   New findings in the roles of Cyclin-dependent Kinase inhibitors 2B Antisense RNA 1 (CDKN2B-AS1) rs1333049 G/C and rs4977574 A/G variants on the risk to coronary heart disease.

  33080691   Association of ANRIL polymorphisms with coronary artery disease: A systemic meta-analysis.

  33186076   Long non-coding RNA ANRIL polymorphisms in papillary thyroid cancer and its severity.