SNP information rs3798220

Research and publications:

  17569884   A polymorphism in the protease-like domain of apolipoprotein(a) is associated with severe coronary artery disease.

  17975119   Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study.

  18682748   Analysis of 17,576 potentially functional SNPs in three case-control studies of myocardial infarction.

  18775538   Polymorphism in the apolipoprotein(a) gene, plasma lipoprotein(a), cardiovascular disease, and low-dose aspirin therapy.

  19060906   Common variants at 30 loci contribute to polygenic dyslipidemia.

  19880117   The I4399M variant of apolipoprotein(a) is associated with increased oxidized phospholipids on apolipoprotein B-100 particles.

  20032323   Genetic variants associated with Lp(a) lipoprotein level and coronary disease.

  20435227   Clinical assessment incorporating a personal genome.

  20605575   Single variants can explain the association between coronary heart disease and haplotypes in the apolipoprotein(a) locus.

  20729558   Improved prediction of cardiovascular disease based on a panel of single nucleotide polymorphisms identified through genome-wide association studies.

  20941391   Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study

  20971364   A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.

  21127300   Genetic variation in LPAL2, LPA, and PLG predicts plasma lipoprotein(a) level and carotid artery disease risk.

  21252144   Lipoprotein(a) genetic variants associated with coronary and peripheral vascular disease but not with stroke risk in the Heart Protection Study.

  21283670   Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a) levels in African Americans.

  21369780   Genome-wide association studies in atherosclerosis.

  21378990   Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

  21749171   Lipoprotein(a): genotype-phenotype relationship and impact on atherogenic risk.

  21875899   Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour.

  21966275   Large-scale gene-centric analysis identifies novel variants for coronary artery disease.

  22192511   KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly.

  22199011   Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies.

  22560621   Cost-effectiveness model of use of genetic testing as an aid in assessing the likely benefit of aspirin therapy for primary prevention of cardiovascular disease.

  22588700   Genetics of coronary artery disease in the 21st century.

  22649660   Genomes, populations and diseases: ethnic genomics and personalized medicine.

  22898070   Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.

  23100282   Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.

  23278389   Two rare variants explain association with acute myocardial infarction in an extended genomic region including the apolipoprotein(A) gene.

  23375930   Extreme lipoprotein(a) levels and improved cardiovascular risk prediction.

  23468967   Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies.

  23735648   Validation and quantification of genetic determinants of lipoprotein-a levels and predictive value for angiographic coronary artery disease.

  24161338   Elevated lipoprotein(a) and risk of aortic valve stenosis in the general population.

  24475106   Genetic variants associated with myocardial infarction and the risk factors in Chinese population.

  24776095   LPA rs10455872 polymorphism is associated with coronary lesions in Brazilian patients submitted to coronary angiography.

  24834361   Update on abdominal aortic aneurysm research: from clinical to genetic studies.

  24932356   Genetics of coronary artery disease: an update.

  24988487   Coherent somatic mutation in autoimmune disease.

  25542012   Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.

  25575512   Evidence for several independent genetic variants affecting lipoprotein (a) cholesterol levels.

  25897256   Personalized antiplatelet and anticoagulation therapy: applications and significance of pharmacogenomics.

  26302166   Lack of association of rs3798220 with small apolipoprotein(a) isoforms and high lipoprotein(a) levels in East and Southeast Asians.

  26776177   TESTING POPULATION-SPECIFIC QUANTITATIVE TRAIT ASSOCIATIONS FOR CLINICAL OUTCOME RELEVANCE IN A BIOREPOSITORY LINKED TO ELECTRONIC HEALTH RECORDS: LPA AND MYOCARDIAL INFARCTION IN AFRICAN AMERICANS.

  26847647   Experimental Biology for the Identification of Causal Pathways in Atherosclerosis.

  26892960   From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.

  26896185   Human Genetics and the Causal Role of Lipoprotein(a) for Various Diseases.

  26900838   Apolipoprotein(a) Kringle-IV Type 2 Copy Number Variation Is Associated with Venous Thromboembolism.

  26934567   Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

  26946290   Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk.

  26958643   Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.

  26971241   Influence of Genetic Risk Factors on Coronary Heart Disease Occurrence in Afro-Caribbeans.

  27189168   The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease.

  27386434   Zinc Finger 259 Gene Polymorphism rs964184 is Associated with Serum Triglyceride Levels and Metabolic Syndrome.

  27417585   Lipoprotein Apheresis for Lipoprotein(a)-Associated Cardiovascular Disease: Prospective 5 Years of Follow-Up and Apolipoprotein(a) Characterization.

  27621937   A Case-Control Study of the Relationship Between SLC22A3-LPAL2-LPA Gene Cluster Polymorphism and Coronary Artery Disease in the Han Chinese Population.

  27716211   A 19-SNP coronary heart disease gene score profile in subjects with type 2 diabetes: the coronary heart disease risk in type 2 diabetes (CoRDia study) study baseline characteristics.

  27831500   LPA Gene, Ethnicity, and Cardiovascular Events.

  28059143   Influence of coronary artery disease and subclinical atherosclerosis related polymorphisms on the risk of atherosclerosis in rheumatoid arthritis.

  28167353   Genetic risk analysis of coronary artery disease in Pakistani subjects using a genetic risk score of 21 variants.

  28209224   Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

  28408323   Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis.

  28426714   A genetic risk score for CAD, psychological stress, and their interaction as predictors of CAD, fatal MI, non-fatal MI and cardiovascular death.

  28566218   Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

  28632940   Characterization of the I4399M variant of apolipoprotein(a): implications for altered prothrombotic properties of lipoprotein(a).

  28686695   Coronary artery disease-associated genetic variants and biomarkers of inflammation.

  28705542   Effect of Coronary Artery Disease risk SNPs on serum cytokine levels and cytokine imbalance in Premature Coronary Artery Disease.

  28772107   Family-specific aggregation of lipid GWAS variants confers the susceptibility to familial hypercholesterolemia in a large Austrian family.

  29128868   Association of LPA Variants With Aortic Stenosis: A Large-Scale Study Using Diagnostic and Procedural Codes From Electronic Health Records.

  29309886   The association of polymorphic variants, rs2267788, rs1333049 and rs2383207 with coronary artery disease, its severity and presentation in North Indian population.

  29695241   Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.

  29972410   Genetic Risk Analysis of Coronary Artery Disease in a Population-based Study in Portugal, Using a Genetic Risk Score of 31 Variants.

  29988570   GWAS Reveal Targets in Vessel Wall Pathways to Treat Coronary Artery Disease.

  30594920   Investigation of LPA sequence variants rs6415084, rs3798220 with conventional coronary artery disease in Iranian CAD patients.

  31113255   Relationship between LPA SNPs and inflammatory burden in patients with preeclampsia to address future cardiovascular risk.

  31327478   Statin treatment increases lipoprotein(a) levels in subjects with low molecular weight apolipoprotein(a) phenotype.

  31481563   Cohort profile: role of lipoproteins in cardiovascular disease-the LipidCardio study.

  31824394   The Association of SNPs Located in the CDKN2B-AS1 and LPA Genes With Carotid Artery Stenosis and Atherogenic Stroke.

  31845553   Precision Medicine and Cardiovascular Health: Insights from Mendelian Randomization Analyses.

  32152647   Lipoprotein(a) plasma levels are not associated with incident microvascular complications in type 2 diabetes mellitus.

  32220223   Association between lipoprotein(a) (Lp(a)) levels and Lp(a) genetic variants with coronary artery calcification.

  32681934   Coronary artery disease and the risk-associated LPA variants, rs3798220 and rs10455872, in patients with suspected familial hypercholesterolaemia.

  33170161   Genetic test for the prescription of diets in support of physical activity.

  33872986   Prevalence and influence of LPA gene variants and isoform size on the Lp(a)-lowering effect of pelacarsen.

  34137427   Genetic information improves the prediction of major adverse cardiovascular events in the GENEMACOR population.

  34276231   Epicardial Adipose Tissue: The Genetics Behind an Emerging Cardiovascular Risk Marker.

  35246583   Elevated lipoprotein(a) and genetic polymorphisms in the LPA gene may predict cardiovascular events.

  35379196   Analysis of 61 SNPs from the CAD specific genomic loci reveals unique set of SNPs as significant markers in the Southern Indian population of Hyderabad.

  36097220   Genetic risk factors have a substantial impact on healthy life years.