SNP information rs11209026

Research and publications:

  17068223   A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.

  17236132   A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes.

  17447842   Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4.

  17508420   Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype.

  17618837   Association of interleukin-23 receptor gene variants with susceptibility to Crohn's disease in children.

  17678723   Investigation of the IL23R gene in a Spanish rheumatoid arthritis cohort.

  17678845   Replication of an association between IL23R gene polymorphism with inflammatory bowel disease.

  17684544   Systematic association mapping identifies NELL1 as a novel IBD disease gene.

  17786191   rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: a combined analysis of IL23R, CARD15 and OCTN1/2 variants.

  17804789   A genome-wide association study of Crohn's disease in the Quebec founder population identified several validated disease loci.

  17877509   Heterozygosity for IL23R p.Arg381Gln provides a protective effect not only against Crohn's disease, but also against ulcerative colitis.

  17894849   IL23R R381Q and ATG16L1 T300A were strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease.

  17901940   Association analysis of IL-12B and IL-23R polymorphisms in myocardial infarction.

  17940599   Assembly of inflammation-related genes for pathway-focused genetic analysis.

  17952073   Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

  18045485   The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes

  18047539   Association between genetic variants in the IL-23R gene and early-onset Crohn's disease: results from a case-control and family study among Canadian children.

  18047540   ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands.

  18073300   Interleukin (IL)-23 receptor is a major susceptibility gene for Graves' ophthalmopathy: the IL-23/T-helper 17 axis extends to thyroid autoimmunity.

  18199597   The IL23R Arg381Gln non-synonymous polymorphism confers susceptibility to ankylosing spondylitis.

  18200510   CARD15 and IL23R influence Crohn's disease susceptibility but not disease phenotype in a Brazilian population.

  18219280   Polymorphisms of the IL12B and IL23R genes are associated with psoriasis.

  18224312   Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment

  18368064   IL23R: a susceptibility locus for celiac disease and multiple sclerosis?

  18369459   A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.

  18383363   Association of interleukin-23 receptor variants with ankylosing spondylitis.

  18383521   IL23R and IL12B polymorphisms in Spanish IBD patients: no evidence of interaction.

  18438406   Genetic determinants of ulcerative colitis include the ECM1 locus and five loci involved in Crohn's disease.

  18470928   IL23R haplotypes confer a high population risk of developing Crohn's disease.

  18499543   ATG16L1 and IL23 receptor (IL23R) genes are associated with disease susceptibility in Hungarian CD patients.

  18609743   Genetics of psoriasis and psoriatic arthritis: update and future direction.

  18647855   Evidence for association of an interleukin 23 receptor variant independent of the R381Q variant with rheumatoid arthritis.

  18698678   Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy.

  18715515   Lack of evidence linking primary sclerosing cholangitis and primary biliary cirrhosis with Crohn's disease risk alleles in Polish patients.

  18758464   Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.

  18800148   Genetic variants of the IL-23R pathway: association with psoriatic arthritis and psoriasis vulgaris, but no specific risk factor for arthritis.

  19021011   Association studies of the IL-23R gene in autoimmune thyroid disease in the Japanese population.

  19035472   Investigation of association of the IL12B and IL23R genes with psoriatic arthritis.

  19040306   Association of interleukin 23 receptor variants with psoriatic arthritis.

  19103525   IL-23R Arg381Gln polymorphism in Chilean patients with inflammatory bowel disease.

  19122664   Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.

  19161620   An open access database of genome-wide association results

  19165485   Interleukin-23 receptor (IL-23R) gene polymorphisms in acquired aplastic anemia.

  19174780   Confirmation of multiple susceptibility loci for Crohn's disease in a large Dutch-Belgian cohort.

  19175939   IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease.

  19182814   New insights into the pathogenesis and genetics of psoriatic arthritis.

  19189980   Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case-control study and meta-analysis of published series.

  19294505   Genetic association of nonsynonymous variants of the IL23R with familial and sporadic inflammatory bowel disease in women.

  19468064   Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.

  19522770   Variants of the IL23R gene are associated with ankylosing spondylitis but not with Sjögren syndrome in Hungarian population samples.

  19590455   Association of IL23R p.381Gln and ATG16L1 p.197Ala with Crohn disease in the Czech population.

  19705136   Genetic evidence for involvement of the IL23 pathway in Thai psoriatics.

  19877036   Association of ERAP1, but not IL23R, with ankylosing spondylitis in a Han Chinese population.

  19915572   Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

  19918037   Association of interleukin 23 receptor polymorphisms with anti-topoisomerase-I positivity and pulmonary hypertension in systemic sclerosis.

  20062062   Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.

  20082483   NOD2, IL23R and ATG16L1 polymorphisms in Lithuanian patients with inflammatory bowel disease.

  20155851   NOD2 status and human ileal gene expression.

  20157760   Interleukin-23 receptor genetic polymorphisms and susceptibility to Crohn's disease: a meta-analysis.

  20173782   Prognostic significance of genetic variants in the IL-23/Th17 pathway for the outcome of T cell-depleted allogeneic stem cell transplantation.

  20177049   Insufficient evidence for association of NOD2/CARD15 or other inflammatory bowel disease-associated markers on GVHD incidence or other adverse outcomes in T-replete, unrelated donor transplantation.

  20192940   Association of interleukin-23 receptor gene variant rs11209026 with Crohn's disease in German children.

  20228799   Genome-wide association identifies multiple ulcerative colitis susceptibility loci.

  20380008   Polymorphism of the NOD2/CARD15, ATG16L1 and IL23R genes and the onset of Crohn's disease in childhood.

  20444268   Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets

  20454450   Evidence that STAT4 is a common autoimmune gene: rs7574865 is associated with Crohn's disease of the colon and early onset of the disease.

  20485703   A replication and meta-analysis of 13,000 cases determines the risk of interleukin-23 receptor and autophagy-related 16-like variants 1 in Crohn's disease.

  20505004   On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data.

  20537165   CTLA4 variants may interact with the risk of Crohn's disease mediated by IL23R and NOD2.

  20606885   Genetics of psoriasis and psoriatic arthritis.

  20650992   Association of inflammatory bowel disease risk loci with sarcoidosis, and its acute and chronic subphenotypes.

  20827186   Defining genetic risk for graft-versus-host disease and mortality following allogeneic hematopoietic stem cell transplantation

  20846217   Association of linear growth impairment in pediatric Crohn's disease and known growth locus: a pilot study.

  20886065   Molecular reclassification of Crohn's disease by cluster analysis of genetic variants.

  20953190   A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

  21072187   Evidence of significant overlap between common risk patterns for Crohn's disease and ankylosing spondylitis.

  21079743   Interaction of Crohn's disease susceptibility genes in an Australian pediatric cohort.

  21090563   Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab results in dysregulation of gastrointestinal immunity in patients with advanced melanoma.

  21102463   Genome-wide meta-analysis increases the number of confirmed susceptibility loci for Crohn's disease to 71.

  21152001   The association of 1q32 and STAT3 variants with ankylosing spondylitis suggests genetic overlap with Crohn's disease.

  21206965   Polymorphisms of IL23R, NOD2/CARD15, ATG16L1 and PHOX2B in a group of patients with Crohn's disease and correlation with subphenotypes.

  21253534   The IL23R and IL12B SNPs and haplotypes are strongly associated with the risk of Crohn's disease in the New Zealand population.

  21253733   Interleukin-23 receptor genetic polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis.

  21281511   Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis.

  21297633   Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

  21304977   An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.

  21333900   The role of genetics in IBS

  21487504   Immunopathogenesis of inflammatory bowel disease.

  21548950   Evaluation of 22 genetic variants with risk for Crohn's disease in an Ashkenazi Jewish population: a case-control study.

  21559375   A genetic risk score combining ten psoriasis risk loci improves disease prediction.

  21559399   CEACAM6 gene variants in inflammatory bowel disease.

  21730793   The influence of risk alleles for Crohn's disease and smoking on the location of the disease.

  21743469   Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility.

  21846945   Association of interleukin 23 receptor gene with sarcoidosis.

  21858135   Efficient replication of over 180 genetic associations with self-reported medical data.

  21896776   Role of interleukin-23 (IL-23) receptor signaling for IL-17 responses in human Lyme disease.

  22076442   A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations.

  22089529   Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis.

  22123319   A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma.

  22154103   Genetic variability in IL23R and risk of colorectal adenoma and colorectal cancer.