SNP information rs11206510

Research and publications:

  18193044   Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.

  18852197   Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants

  19060906   Common variants at 30 loci contribute to polygenic dyslipidemia.

  19060910   Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

  19060911   Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

  19198609   Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

  19435741   Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.

  19750184   Genome-wide association studies for atherosclerotic vascular disease and its risk factors.

  19951432   Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease

  19956433   Genetics of coronary artery disease: focus on genome-wide association studies.

  20018036   Using a latent growth curve model for an integrative assessment of the effects of genetic and environmental factors on multiple phenotypes.

  20434130   Interpretation of association signals and identification of causal variants from genome-wide association studies.

  20440292   Early identification of cardiovascular risk using genomics and proteomics.

  20576952   Minor allele C of chromosome 1p32 single nucleotide polymorphism rs11206510 confers risk of ischemic stroke in the Chinese Han population.

  20699424   Effects of PCSK9 genetic variants on plasma LDL cholesterol levels and risk of premature myocardial infarction in the Italian population.

  20729558   Improved prediction of cardiovascular disease based on a panel of single nucleotide polymorphisms identified through genome-wide association studies.

  20835900   Genetics of diabetes complications.

  20839009   Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica.

  20864672   Genetic variants influencing circulating lipid levels and risk of coronary artery disease.

  20876667   Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

  20971364   A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.

  21239051   Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.

  21369780   Genome-wide association studies in atherosclerosis.

  21378990   Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

  21463265   Association of SNP rs17465637 on chromosome 1q41 and rs599839 on 1p13.3 with myocardial infarction in an American caucasian population.

  21738485   Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.

  21829380   Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability.

  21860704   Implications of discoveries from genome-wide association studies in current cardiovascular practice.

  21862702   Mechanisms and genetic determinants regulating sterol absorption, circulating LDL levels, and sterol elimination: implications for classification and disease risk.

  21875899   Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour.

  22042884   Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study.

  22144573   Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.

  22151179   Genotype-informed estimation of risk of coronary heart disease based on genome-wide association data linked to the electronic medical record.

  22152955   Genetic susceptibility to coronary heart disease in type 2 diabetes: 3 independent studies.

  22216278   Large scale association analysis identifies three susceptibility loci for coronary artery disease.

  22363065   Are myocardial infarction--associated single-nucleotide polymorphisms associated with ischemic stroke?

  22429504   Genetic predisposition to coronary heart disease and stroke using an additive genetic risk score: a population-based study in Greece.

  22588700   Genetics of coronary artery disease in the 21st century.

  22848412   Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts.

  22882272   Genetic variants associated with myocardial infarction in the PSMA6 gene and Chr9p21 are also associated with ischaemic stroke.

  23050023   Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.

  23098650   Impact of variants within seven candidate genes on statin treatment efficacy.

  23380588   Association between PCSK9 and LDLR gene polymorphisms with coronary heart disease: case-control study and meta-analysis.

  23468967   Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies.

  24190014   BRG1 variant rs1122608 on chromosome 19p13.2 confers protection against stroke and regulates expression of pre-mRNA-splicing factor SFRS3.

  24219970   Common genetic variants do not associate with CAD in familial hypercholesterolemia.

  24251769   LDL-c-linked SNPs are associated with LDL-c and myocardial infarction despite lipid-lowering therapy in patients with established vascular disease.

  24319689   The roles of genetic polymorphisms and human immunodeficiency virus infection in lipid metabolism.

  24932356   Genetics of coronary artery disease: an update.

  24950029   Serum lipoprotein composition and vitamin D metabolite levels in clinically isolated syndromes: Results from a multi-center study.

  25542012   Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.

  26266351   Association of Zinc Finger, C3HC-Type Containing 1 (ZC3HC1) rs11556924 Genetic Variant With Hypertension in a Finnish Population, the TAMRISK Study.

  26661904   Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods.

  26839654   Genetics of coronary artery disease and myocardial infarction.

  26847647   Experimental Biology for the Identification of Causal Pathways in Atherosclerosis.

  26892960   From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.

  26934567   Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.

  26946290   Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk.

  26950853   Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium.

  26958643   Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.

  27042264   Genetics of cardiovascular and renal complications in diabetes.

  27158361   Polymorphism rs2200733 at chromosome 4q25 is associated with atrial fibrillation recurrence after radiofrequency catheter ablation in the Chinese Han population.

  27189168   The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease.

  27294088   Genetics of the acute coronary syndrome.

  27479212   Common Variants in the TBX5 Gene Associated with Atrial Fibrillation in a Chinese Han Population.

  27908689   PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.

  28209224   Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

  28330911   PCSK9 variant, long-chain n-3 PUFAs, and risk of nonfatal myocardial infarction in Costa Rican Hispanics.

  28379035   Polygenic hypercholesterolemia: examples of GWAS results and their replication in the Czech-Slavonic population.

  28426714   A genetic risk score for CAD, psychological stress, and their interaction as predictors of CAD, fatal MI, non-fatal MI and cardiovascular death.

  28577571   Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

  28686695   Coronary artery disease-associated genetic variants and biomarkers of inflammation.

  29109005   Evaluation of PCSK9 levels and its genetic polymorphisms in women with polycystic ovary syndrome.

  29188294   Genetic Association of Lipids and Lipid Drug Targets With Abdominal Aortic Aneurysm: A Meta-analysis.

  29695241   Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.

  31845553   Precision Medicine and Cardiovascular Health: Insights from Mendelian Randomization Analyses.

  32176569   Multiomics Analysis Coupled with Text Mining Identify Novel Biomarker Candidates for Recurrent Cardiovascular Events.

  33166319   PCSK9 loss of function is protective against extra-coronary atherosclerotic cardiovascular disease in a large multi-ethnic cohort.

  33488114   Impact of PCSK9, WDR12, CDKN2A, and CXCL12 Polymorphisms in Jordanian Cardiovascular Patients on Warfarin Responsiveness and Sensitivity.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.

  35387194   Personalized Dietary Recommendations Based on Lipid-Related Genetic Variants: A Systematic Review.