SNP information rs10757278

Research and publications:

  18048766   Four SNPs on chromosome 9p21 in a South Korean population implicate a genetic locus that confers high cross-race risk for development of coronary artery disease.

  18066490   Association between four SNPs on chromosome 9p21 and myocardial infarction is replicated in an Italian population.

  18176561   The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm.

  18224312   Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment

  18362232   Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease.

  18443000   Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study.

  18459066   A common variant on chromosome 9p21 affects the risk of early-onset coronary artery disease.

  18469204   Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians

  18505420   Four SNPS on chromosome 9p21 confer risk to premature, familial CAD and MI in an American Caucasian population (GeneQuest).

  18675980   Novel genetic variants linked to coronary artery disease by genome-wide association are not associated with carotid artery intima-media thickness or intermediate risk phenotypes.

  18704761   Molecular genetics of myocardial infarction.

  18854858   Sequence variant on 9p21 is associated with the presence of abdominal aortic aneurysm disease but does not have an impact on aneurysmal expansion.

  18925945   Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study.

  18987759   Genetic testing for atherosclerosis risk: inevitability or pipe dream?

  19002430   Type 2 diabetes-associated genetic variants discovered in the recent genome-wide association studies are related to gestational diabetes mellitus in the Korean population

  19033589   Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes.

  19171343   Lack of association of chromosome 9p21.3 genotype with cardiovascular structure and function in persons with stable coronary artery disease: The Heart and Soul Study.

  19173706   The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis.

  19207022   Genome-wide association studies of coronary artery disease and heart failure: where are we going?

  19214202   Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis.

  19293724   The myocardial infarction associated CDKN2A/CDKN2B locus on chromosome 9p21 is associated with stroke independently of coronary events in patients with hypertension.

  19319159   Variant on 9p21 strongly associates with coronary heart disease, but lacks association with common stroke.

  19329499   A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study.

  19343170   INK4/ARF transcript expression is associated with chromosome 9p21 variants linked to atherosclerosis.

  19359634   Update on the genetics of stroke and cerebrovascular disease 2008.

  19463184   Worldwide patterns of haplotype diversity at 9p21.3, a locus associated with type 2 diabetes and coronary heart disease.

  19474294   Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

  19475673   Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke.

  19503741   Coding variant Met72Thr in the PEDF gene and risk of neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.

  19578363   New common variants affecting susceptibility to basal cell carcinoma.

  19578366   Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.

  19672284   Association of the TGF-beta receptor genes with abdominal aortic aneurysm.

  19750184   Genome-wide association studies for atherosclerotic vascular disease and its risk factors.

  19752551   Polymorphisms associated with both noncardioembolic stroke and coronary heart disease: vienna stroke registry.

  19753309   SOD2 gene polymorphisms in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.

  19805338   A quantitative model for age-dependent expression of the p16INK4a tumor suppressor.

  19819472   Common genetic variants on chromosome 9p21 predict perioperative myocardial injury after coronary artery bypass graft surgery.

  19860767   Genetic cardiovascular risk factors and age-related macular degeneration.

  19888323   Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.

  19956433   Genetics of coronary artery disease: focus on genome-wide association studies.

  19956784   Association of variation in the chromosome 9p21 locus with myocardial infarction versus chronic coronary artery disease.

  20031605   9p21 is a shared susceptibility locus strongly for coronary artery disease and weakly for ischemic stroke in Chinese Han population.

  20031606   The 9p21 myocardial infarction risk allele increases risk of peripheral artery disease in older people.

  20175863   The genetics of ischaemic stroke.

  20190001   The relationship between smoking and replicated sequence variants on chromosomes 8 and 9 with familial intracranial aneurysm.

  20227257   Polymorphisms in the platelet-specific collagen receptor GP6 are associated with risk of nonfatal myocardial infarction in Caucasians

  20309761   Genotype-based risk and pharmacogenetic sampling in clinical trials.

  20386740   Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression.

  20395606   Chromosome 9p21 in ischemic stroke: population structure and meta-analysis.

  20395613   Confirmation of an association of single-nucleotide polymorphism rs1333040 on 9p21 with familial and sporadic intracranial aneurysms in Japanese patients.

  20440292   Early identification of cardiovascular risk using genomics and proteomics.

  20453838   Genome-wide association study identifies five new breast cancer susceptibility loci.

  20601674   Bivariate genetic association of KIAA1797 with heart rate in American Indians: the Strong Heart Family Study.

  20605023   Association of an allele on chromosome 9 and abdominal aortic aneurysm.

  20622881   Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.

  20696043   Replication of the association of chromosomal region 9p21.3 with generalized aggressive periodontitis (gAgP) using an independent case-control cohort.

  20729229   The chromosome 9p21 risk locus is associated with angiographic severity and progression of coronary artery disease.

  20858033   Haplotypes on 9p21 modify the risk for coronary artery disease among Indians.

  20871623   Genetic analysis of six SNPs in candidate genes associated with high cross-race risk of development of thoracic aortic aneurysms and dissections in Chinese Han population.

  20923989   Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls.

  20974651   Association between genetic variation on chromosome 9p21 and aneurysmal subarachnoid haemorrhage.

  20981302   Genome-wide association study of coronary artery disease.

  21088391   Exploration of a hypothesized independent association of a common 9p21.3 gene variant and ischemic stroke in patients with and without angiographic coronary artery disease.

  21146954   Genes and abdominal aortic aneurysm

  21151960   Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk.

  21152093   Sex differential genetic effect of chromosome 9p21 on subclinical atherosclerosis.

  21270820   A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry.

  21307941   9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response.

  21315566   Type 2 diabetes and polymorphisms on chromosome 9p21: a meta-analysis.

  21372283   Chromosome 9p21 haplotypes and prognosis in white and black patients with coronary artery disease.

  21375403   The relationship between polymorphisms on chromosome 9p21 and age of onset of coronary heart disease in black and white women.

  21385355   Six sequence variants on chromosome 9p21.3 are associated with a positive family history of myocardial infarction: a multicenter registry.

  21424681   Peripheral arterial disease in diabetes: is there a role for genetics?

  21444365   Association of a sequence variant in DAB2IP with coronary heart disease.

  21698238   Replication of putative susceptibility loci from genome-wide association studies associated with coronary atherosclerosis in Chinese Han population.

  21705410   The association between variants on chromosome 9p21 and inflammatory biomarkers in ethnically diverse women with coronary heart disease: a pilot study.

  21860704   Implications of discoveries from genome-wide association studies in current cardiovascular practice.

  21896860   Association of genetic variation on chromosome 9p21 with polypoidal choroidal vasculopathy and neovascular age-related macular degeneration.

  21912604   Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences.

  22022235   The effect of chromosome 9p21 variants on cardiovascular disease may be modified by dietary intake: evidence from a case/control and a prospective study.

  22034006   Variants on chromosome 9p21.3 correlated with ANRIL expression contribute to stroke risk and recurrence in a large prospective stroke population.

  22042884   Association of genetic variants and incident coronary heart disease in multiethnic cohorts: the PAGE study.

  22151179   Genotype-informed estimation of risk of coronary heart disease based on genome-wide association data linked to the electronic medical record.

  22198471   Genetic variants at chromosome 9p21, 10p15 and 10q22 and breast cancer susceptibility in a Chinese population.

  22216169   Rationale and design of the Leipzig (LIFE) Heart Study: phenotyping and cardiovascular characteristics of patients with coronary artery disease.

  22269347   Transcriptional enhancers in development and disease.

  22322877   Chromosome 9p21 single nucleotide polymorphisms are not associated with recurrent myocardial infarction in patients with established coronary artery disease.

  22400124   Genomic research to identify novel pathways in the development of abdominal aortic aneurysm.

  22403240   Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study.

  22509112   Genetic associations in polypoidal choroidal vasculopathy: a systematic review and meta-analysis.

  22815632   COL1A2 polymorphic markers confer an increased risk of neovascular age-related macular degeneration in a Han Chinese population.

  22856518   Higher incidence of death in multi-vessel coronary artery disease patients associated with polymorphisms in chromosome 9p21.

  22946666   The rs10757278 polymorphism of the 9p21.3 locus is associated with premature coronary artery disease in Polish patients.

  22975211   Meta-analysis of genetic association of chromosome 9p21 with early-onset coronary artery disease.

  23086272   Association between 9p21.3 genomic markers and coronary artery disease in East Asians: a meta-analysis involving 9,813 cases and 10,710 controls.

  23134948   Association between 9p21 genetic variants and mortality risk in a prospective cohort of patients with type 2 diabetes (ZODIAC-15).

  23388737   Association of single nucleotide polymorphisms on chromosome 9p21.3 with cardiovascular death in kidney transplant recipients.

  23454037   Polymorphisms on chromosome 9p21 confer a risk for acute coronary syndrome in a Chinese Han population.

  23535969   Chromosome 9p21 rs10757278 polymorphism is associated with the risk of metabolic syndrome.

  23733552   Genetic risk factors for intracranial aneurysms: a meta-analysis in more than 116,000 individuals.